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It was determined that alkaloid extract mainly contain hyoscyamine and scopolamine. Conclusions These results confirm the folkloric usage of the plant and suggest that the alkaloid content of the plant could be responsible for the insecticidal activity.An unfavorable lipid profile and being overweight are known mediators in the development of cardiovascular disease (CVD) risk. The effect of diet, particularly high in protein, remains under discussion. Therefore, this study examines the effects of a high-protein (HP) diet on cardiometabolic health and vascular function (i.e., endothelial function, arterial stiffness, and retinal microvascular structure), and the possible association with plasma endocannabinoids and endocannabinoid-related compounds in overweight participants. Thirty-eight participants (64.5 ± 5.9 (mean ± SD) years; body mass index (BMI) 28.9 ± 4.0 kg/m2) were measured for 48 h in a respiration chamber after body-weight maintenance for approximately 34 months following weight reduction. Diets with either a HP (n = 20) or moderate protein (MP; n = 18) content (25%/45%/30% vs. 15%/55%/30% protein/carbohydrate/fat) were provided in energy balance. Validated markers for cardiometabolic health (i.e., office blood pressure (BP) and serum lipoproteiention. Furthermore, our data indicate a possible association between OEA and PEA with TC and LDL cholesterol.The development of new technologies, the expansion of the Internet, and the emergence of dating apps (e.g., Tinder, Grindr) in recent years have changed the way to meet and approach potential romantic and/or sexual partners. The recent phenomenon has led to some gaps in the literature on individual differences (sociodemographic variables and personality traits) between users (previous and current users) and non-users of dating apps. Thus, the aim of this study was to analyze the relationship between using dating apps, sociodemographics (gender, age, sexual orientation, and relationship status), and bright and dark personality traits. Participants were 1705 university students (70% women, 30% men), aged between 18 and 26 (M = 20.60, SD = 2.09), who completed several online questionnaires. Through multinomial logistic regression analyses, it was found that men, older youth, and members of sexual minorities were more likely to be current and previous dating apps users. Being single and higher scores in open-mindedness were associated with higher probability to be current dating apps user. The dark personality showed no predictive ability. The discussion highlights the usefulness of knowing and considering the sociodemographic background and the characteristics of personality patterns in the design and implementation of preventive and promotion programs of healthy romantic and sexual relationships to improve people's better health and well-being.The association between bacterial as well as viral gut microbiota imbalance and carcinogenesis has been intensively analysed in many studies; nevertheless, the role of fungal gut microbiota (mycobiota) in colorectal, oral, and pancreatic cancer development is relatively new and undiscovered field due to low abundance of intestinal fungi as well as lack of well-characterized reference genomes. Several specific fungi amounts are increased in colorectal cancer patients; moreover, it was observed that the disease stage is strongly related to the fungal microbiota profile; thus, it may be used as a potential diagnostic biomarker for adenomas. Candida albicans, which is the major microbe contributing to oral cancer development, may promote carcinogenesis via several mechanisms, mainly triggering inflammation. Early detection of pancreatic cancer provides the opportunity to improve survival rate, therefore, there is a need to conduct further studies regarding the role of fungal microbiota as a potential prognostic tool to diagnose this cancer at early stage. Additionally, growing attention towards the characterization of mycobiota may contribute to improve the efficiency of therapeutic methods used to alter the composition and activity of gut microbiota. The administration of Saccharomyces boulardii in oncology, mainly in immunocompromised and/or critically ill patients, is still controversial.Styrene-butadiene rubber mixtures with four types of carbon black were studied in this paper. The mechanical properties, including the ability to damp mechanical vibration, were investigated, along with dynamical mechanical analysis (DMA). It has been found that carbon black types N 110 and N 330, having the largest specific surface area and the smallest particle diameter, provide a good stiffening effect. These particles have significant interactions between the rubber, resulting in good reinforcement. On the other hand, the carbon black N 990 type has a lower reinforcing effect and improved vibration damping properties at higher excitation frequencies due to higher dissipation of mechanical energy into heat under dynamic loading. The effect of the number of loading cycles on vibration damping properties of the rubber composites was also investigated in this study. selleckchem It can be concluded that the abovementioned properties of the investigated rubber composites correspond to physical-mechanical properties of the applied carbon black types.Better and more efficient membranes are needed to face imminent and future scientific, technological and societal challenges. New materials endowed with enhanced properties are required for the preparation of such membranes. Metal and Covalent Organic Frameworks (MOFs and COFs) are a new class of crystalline porous materials with large surface area, tuneable pore size, structure, and functionality, making them a perfect candidate for membrane applications. In recent years an enormous number of articles have been published on the use of MOFs and COFs in preparation of membranes for various applications. This review gathers the work reported on the synthesis and preparation of membranes containing MOFs and COFs in the last 10 years. Here we give an overview on membranes and their use in separation technology, discussing the essential factors in their synthesis as well as their limitations. A full detailed summary of the preparation and characterization methods used for MOF and COF membranes is given. Finally, applications of these membranes in gas and liquid separation as well as fuel cells are discussed.