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routes was obtained in the smokers. None of the TXA protocols was associated with a higher incidence of complications or early reoperation following TKA surgery. Key words tranexamic acid, topical application, intravenous application, combined administration, diabetes, obesity, BMI, smoking, blood loss, hidden blood loss, total knee arthroplasty, complications.PURPOSE OF THE STUDY To evaluate the results of incisional open biopsies and ultrasound-guided core needle biopsies for musculoskeletal lesions in extremity and limb girdle locations. MATERIAL AND METHODS In 2019, 176 open incisional biopsies were performed at our department, 113 from bone lesions and 63 from soft tissue lesions. In the period of September 2019 to February 2020, we started performing also ultrasound-guided core needle biopsies from soft tissue lesions in limited indications, namely in 23 cases. The diagnostic accuracy, complications and pain associated with the procedure were evaluated. RESULTS Of 113 open incisional biopsies of bone, 91.1% was fully representative and 6.2% non-representative with an indication for re-biopsy. In 53 cases another surgical procedure followed, which fully confirmed the diagnosis made based on the biopsy in 79.2%. In 7.5% the diagnosis slightly changed, with no therapeutic impact, in 5.7% the histological grade was changed, and in 7.5% the diagnosis was substantie by 0.1 points. When comparing the group of soft tissue open incisional biopsies and ultrasound-guided core needle biopsies, a statistically significant less pain associated with the procedure was found in the group of core needle biopsies. click here CONCLUSIONS The biopsy of musculoskeletal tumors should be performed at specialty centers for treatment of these rare conditions. In that case it produces good results and is associated with a low rate of complications. Indications for open biopsy or core needle biopsy must be assessed individually. Key words musculoskeletal tumors, bone and soft tissue sarcomas, open incisional biopsy, core needle biopsy, fine needle aspiration biopsy, ultrasound-guided core needle biopsy.PURPOSE OF THE STUDY Supracondylar humerus fracture (SCF) with dislocation is indicated for closed reduction and osteosynthesis. The method achieving the best stability is CRCPP (closed reduction and crossed percutaneous pinning), even though there is a risk of iatrogenic ulnar nerve injury. The CRLPP (closed reduction and lateral percutaneous pinning) method eliminates this risk at the cost of less stable osteosynthesis. The purpose of this study is to compare the SCF stabilisation by CRLPP with the stabilisation by CRCPP in rotationally stable fractures and to identify the risk of iatrogenic ulnar nerve injury, or the failure of osteosynthesis with recurrent dislocation of fragments. MATERIAL AND METHODS The prospective group of the patients with SCF type 1/2 (classification according to Havránek) treated in the period 2016-2018, in whom the method of osteosynthesis (number of implants, method of their insertion), resulting condition and complications (nerve injury, failure of osteosynthesis) were evaluatedNCLUSIONS Based on the results of our study we recommend to stabilise the rotationally stable SCF (type 1/2 according to Havránek) only from the radial column (and thus eliminate the risk of iatrogenic ulnar nerve injury), provided the fracture characteristics allows so. Nonetheless, the CRLPP has its own specific rules for implant entry which have to be adhered to. Key words supracondylar fracture of the humerus, paediatric fractures, closed reduction, percutaneous pinning, lateral percutaneous pinning, iatrogenic ulnar nerve injury, osteosynthesis failure.PURPOSE OF THE STUDY The incidence of pelvic fractures in geriatric population has been increasing. The diagnostic method of first choice is plain pelvic anteroposterior X-ray which, however, mostly reveals merely the pubic rami fractures. The pain caused by undiagnosed lesion of the posterior pelvic segment may substantially reduce the patient s mobility, thus also their self-sufficiency which is crucial in elderly patients. The purpose of this prospective study was to evaluate the incidence of an occult injury to the posterior pelvic ring in patients with an X-ray finding of pubic rami fractures only. MATERIAL AND METHODS Throughout a three-year period (2017-2019), the incidence of an occult injury to the posterior pelvic ring was evaluated by means of a CT scan in 50 patients aged 65 years and over, in whom the plain anteroposterior pelvic radiograph initially revealed only the pubic rami fractures. The mean age of 35 women and 15 men was 76 years (the range of 65-94 years). RESULTS In 15 patients (30%) oninstability, which has to be reflected in treatment strategy. CONCLUSIONS Injuries to the posterior pelvic segment in geriatric population are much more frequent than expected. They are, however, rarely distinguishable on a plain radiograph. Often times, only the pubic rami fractures are clearly visible. The fractures of posterior segment tend to be accompanied by a higher number of complications and a worse prognosis. A reliable method to detect these injuries is the unenhanced CT scan of the pelvis that should be performed routinely in all the patients with pubic rami fractures identified on a radiograph. In cases when pain substantially limits the mobilisation of the patients, minimally invasive surgical treatment should be considered. Key words pelvic ring injury, pubic rami, geriatric population.PURPOSE OF THE STUDY The preoperative planning in habitual dislocation of the patella should take into account all pathologies and the procedure should address all abnormalities. One of them might be also the rotational deformity of the femur. The purpose of this prospective study was to confirm the hypothesis that the only correction of pathological femoral anteversion by derotational intertrochanteric osteotomy (in the absence of another pathology) or the correction of femoral anteversion with simultaneous reconstruction of the patellofemoral joint provide adequate stability for the patellofemoral joint, with respect to the elimination of the risk of recurrent dislocation of the patella. MATERIAL AND METHODS In the course of 15 years, 17 patients (20 knee joints) with habitual dislocation of the patella were included in the study, in whom the CT scan also confirmed the femoral anteversion of 35° and greater. The group was female-dominant, often with BMI > 30. The mean age was 26 years. In 4 cases only derotational intertrochanteric osteotomy was performed, in 16 patients the osteotomy was followed by the stabilization of the patella in the knee region (always individually in dependence on the diagnosed pathology), of whom in 2 cases as the second step procedure because of thrombophilic disorders detected earlier.