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7±29.1minutes. We found 21 metastatic specimens with an average diameter 13.9±6.3mm. The mean activity of the implanted seed was 71.27±21.6MBq (42.8-105) In the reoperated group, thyroglobulin level was 2.08±1.56ng/dl and decreased after surgery to 0.13±0.12ng/dl, P less then .01. Only one case of transient hypoparathyroidism was found in the total group. Conclusions The introduction of RSL in our unit has shown benefits for the patient and medical team, being a safe and effective procedure that also improves surgical programming.Background Adverse childhood experiences (ACEs) are common and related to substance use problems in adulthood. Less is known about these relationships in adolescence and if experiencing ACEs in addition to peer victimization (or bullying) would have an interaction or cumulative effect on the odds of adolescent substance use. Method Data were used from the Well-Being and Experiences Study (The WE Study), a cross-sectional survey of adolescents aged 14-17 years (n = 1002) in Manitoba, Canada collected between July 2017 and October 2018. Statistical methods included descriptive statistics and logistic regression models. Results The prevalence of experiencing any of the 12 ACEs was 75.1 %. The prevalence of any peer victimization (monthly or more often) was 24.1 %. All individual ACEs were associated with increased odds of substance use. No significant interaction effects between ACEs and peer victimization on substance use were found. SEL120-34A Significant cumulative effects were found, indicating that experiencing both ACEs and peer victimization, compared with experiencing ACEs only, significantly increased the odds of substance use among adolescents. Conclusion The odds of substance use becomes significantly greater if the adolescent with a history of ACEs also experiences peer victimization. Further research aimed at effective prevention of ACEs, peer victimization, and substance use is needed.Objective This research examined whether the positive effects of a peer-communicated social norm that reduces risk-taking behaviors persist over time and if a reminder of this peer-communicated safety message has any impact on this outcome. Methods Positive mood in 7- to 9-year olds was induced experimentally and risk taking intentions and behaviors were measured when the child was in a positive and neutral mood state and after they had been exposed to either a safety or neutral peer-communicated social norm message. A few weeks later, half of the participants who experienced the safety social norm message were exposed to a reminder of this message via a slogan and risk-taking measures were taken again when in a heightened positive mood state. Results Exposure to a safety norm successfully counteracted the increase in risk taking associated with a positive mood state. These effects persisted for several weeks regardless of whether the children were exposed to a reminder. Conclusion Manipulating peer social norms holds promise as an approach to produce reductions in children's risk taking and these effects persist at least over several weeks.Introduction While surgical treatment is preferred for Graves' disease with active forms of GO, there are various concepts for treating inactive forms of GO. The goal of radioiodine therapy is to resolve immunogenic hyperthyroidism by damaging the thyroid cells.The effects of the radioiodine dose on an associated inactive GO remain unclear, however. Methodology We conducted a retrospective analysis of 536 patients who received first-time radioiodine therapy to treat Graves' hyperthyroidism. Patients without GO always received 200 Gy of iodine-131. Before the introduction of a differentiated treatment concept, patients with GO also received 200 Gy, while afterwards they received 300 Gy. For further analysis, we formed three patient groups based on GO diagnosis and administered radiation dose and compared their results. The main research question focused on the effect of an increased dose on Graves' orbitopathy. The sub-questions addressed the resolution rate achieved with the higher dose as well as the development of GO in patients who received radioiodine therapy. Results The results show that GO symptoms were improved after radioiodine treatment in 68.5 % of patients treated with 300 Gy but only in 47.5 % of the patients treated with 200 Gy (p = 0.003). While in the 300 Gy group, hyperthyroidism was resolved in 93.2 % of patients, this was achieved in only 68.8 % of patients in the 200 Gy group (p less then /= 0.001). Discussion Especially with an inactive form of GO profit from their hyperthyroidism being quickly and sufficiently resolved. This is achieved significantly better by administering 300 Gy instead of 200 Gy. For this reason, data analysis supports a differentiated dose concept that provides 300 Gy for patients with GO and 200 Gy for patients without GO.Volume averaged CT dose index (CTDIvol) is an important dose index utilized for CT dosimetry. Measurements of CTDIvol are performed in reference cylindrical phantoms of specified diameters. A size-specific dose estimate (SSDE) has been recommended for assessment of doses delivered to individual patients. Evaluation of the SSDE requires the size of the scanned region of the patient to be estimated in terms of water-equivalent diameter (Dw) to allow calculation of a dose value appropriate for the patient. Estimation of Dw, however, may be challenging and time consuming as it requires assessment of Dw for each slice within the scanned region. A study has been carried out to investigate the suitability of using Dw,mid for a single slice at the middle of the scanned region to estimate a value of Dw,mean to apply to all slices. 351 phantoms (158 paediatric and 193 adult) developed from reconstructed CT images of patients were employed. Six scan regions were studied chest, abdomen, pelvis, chest and abdomen, abdomen and pelvis, and the whole trunk. Results show that the use of Dw,mid can lead to over or underestimation of Dw,mean by up to 13% for paediatric and adult patients. SSDE values based on Dw,mid and Dw,mean were assessed for each phantom, and a linear regression analysis was performed. Use of the analysis could provide a simple and practical approach to assessing SSDE for a given scan based on Dw,mid with the root-mean-square errors estimated to be in the range of 1.2%-4.0% for paediatric and 1.2%-5.9% for adults.