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Mechanical motion sensing and monitoring is an important component in the field of industrial automation. Rotary motion is one of the most basic forms of mechanical motion, so it is of great significance for the development of the entire industry to realize rotary motion state monitoring. In this paper, a triboelectric rotary motion sensor (TRMS) with variable amplitude differential hybrid electrodes is proposed, and an integrated monitoring system (IMS) is designed to realize real-time monitoring of industrial-grade rotary motion state. First, the operating principle and monitoring characteristics are studied. The experiment results indicate that the TRMS can achieve rotation speed measurement in the range of 10-1000 rpm with good linearity, and the error rate of rotation speed is less than 0.8%. Besides, the TRMS has an angle monitoring range of 360° and its resolution is 1.5° in bidirectional rotation. Finally, the applications of the designed TRMS and IMS prove the feasibility of self-powered rotary motion monitoring. This work further promotes the development of triboelectric sensors (TESs) in industrial application.Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe respiratory distress and reproductive failure in swine. Modified live virus (MLV) vaccines provide the highest degree of protection and are most often the preferred choice. While somewhat protective, the use of MLVs is accompanied by multiple safety issues, why safer alternatives are urgently needed. Here, we describe the generation of virus replicon particles (VRPs) based on a classical swine fever virus genome incapable of producing infectious progeny and designed to express conserved PRRSV-2 cytotoxic T-cell epitopes. Eighteen pigs matched with the epitopes by their swine leucocyte antigen-profiles were vaccinated (N = 11, test group) or sham-vaccinated (N = 7, control group) with the VRPs and subsequently challenged with PRRSV-2. selleck chemicals The responses to vaccination and challenge were monitored using serological, immunological, and virological analyses. Challenge virus load in serum did not differ significantly between the groups, whereas the virus load in the caudal part of the lung was significantly lower in the test group compared to the control group. The number of peptide-induced interferon-γ secreting cells after challenge was higher and more frequent in the test group than in the control group. Together, our results provide indications of a shapeable PRRSV-specific cell-mediated immune response that may inspire future development of effective PRRSV vaccines.The mechanisms of acute respiratory failure other than inflammation and complicating the SARS-CoV-2 infection are still far from being fully understood, thus challenging the management of COVID-19 patients in the critical care setting. In this unforeseen scenario, the role of an individual's excessive spontaneous breathing may acquire critical importance, being one potential and important driver of lung injury and disease progression. The consequences of this acute lung damage may impair lung structure, forecasting the model of a fragile respiratory system. This perspective article aims to analyze the progression of injured lung phenotypes across the SARS-CoV-2 induced respiratory failure, pointing out the role of spontaneous breathing and also tackling the specific respiratory/ventilatory strategy required by the fragile lung type.This paper reviews and re-analyses data from published studies on the effects of noise exposure on the progression of hearing loss once noise exposure has ceased, focusing particularly on noise exposure during military service. The data are consistent with the idea that such exposure accelerates the progression of hearing loss at frequencies where the hearing loss is absent or mild at the end of military service (hearing threshold levels (HTLs) up to approximately 50 dB HL), but has no effect on or slows the progression of hearing loss at frequencies where the hearing loss exceeds approximately 50 dB. Acceleration appears to occur over a wide frequency range, including 1 kHz. However, each of the studies reviewed has limitations. There is a need for further longitudinal studies of changes in HTLs over a wide range of frequencies and including individuals with a range of HTLs and ages at the end of military service. Longitudinal studies are also needed to establish whether the progression of hearing loss following the end of exposure to high-level sounds depends on the type of noise exposure (steady broadband factory noises versus impulsive sounds).Intravitreal injections (IVTs) of corticosteroids as triamcinolone acetonide (TA) are frequently used for the treatment of many vitreous and retinal disorders. However, IVTs are related to severe ocular complications. Lately, a topical ophthalmic TA-loaded liposomes formulation (TALF) was designed to transport TA into the posterior segment of the eye when instilled on the ocular surface. To evaluate the safety, tolerability, and biological activity of TALF, an animal study and a phase I clinical assay were performed. Moreover, four patients with diabetic macular edema (DME) were treated with TALF in order to explore the biological activity of the formulation. No inflammation, lens opacity, swelling, or increase in intraocular pressure were recorded after the instillation of TALF in any of the animal or clinical studies. Mainly, mild and transient adverse events such as dry eye and burning were reported. TALF significantly improves visual acuity and diminishes central foveal thickness in patients with DME. The current data demonstrate the safety, tolerability, and biological activity of TALF. It seems that TALF can be used topically to treat vitreous and retinal diseases that respond to TA such as DME, avoiding the use of corticosteroid IVTs and their associated hazards.In the traditional layered division multiplexing (LDM) system, by simply adjusting the injection level, the reception performance of the core layer (CL) mobile services will be decreased significantly, resulting in the deterioration of system coverage performance. Thus, it is necessary to improve the performance of the enhanced layer (EL) service reception without affecting the reception threshold of CL service. To achieve this, in this paper, an enhanced LDM (En-LDM) scheme that supports multi-service transmission is proposed for the next-generation broadcasting network. In this scheme, at the transmitter end, part of the low-density parity-check (LDPC) coded data stream of fixed service conveyed in the EL will be extracted out through puncturing, and then, it will be transmitted over the CL of the LDM signal along with the original CL data in a frequency domain multiplexing (FDM) manner. At the receiving end, the punctured data of the EL fixed service will be recovered with a higher signal-to-noise ratio (SNR). Compared to the traditional LDM scheme, the proposed En-LDM scheme can significantly improve the reception performance of fixed services without decreasing the SNR threshold of mobile services. Moreover, the En-LDM can achieve a higher channel capacity than that of the traditional LDM for both the fixed services and the overall services. The superiority of the proposed En-LDM scheme over the traditional LDM scheme is validated by the simulation under the additive white Gaussian noise (AWGN) and fading channels.Abiotrophia defectiva is a rare agent of endocarditis and subacute presentation may delay the diagnosis. We present the case of a 41-year-old male who was admitted to the hospital for further investigation regarding a consumptive syndrome with microcytic anaemia. Past medical history included new-onset mitral insufficiency followed by an ischaemic stroke due to small vessel disease. Thoraco-abdominal computed tomography revealed a splenic infarction. In the presence of two ischaemic events associated with mitral valve disease of unknown aetiology, we considered the possibility of subacute endocarditis. Blood cultures were positive for Abiotrophia defectiva, and transoesophageal echocardiography confirmed the diagnosis. As a subacute presentation of endocarditis, the paucity of symptoms caused a five-month delay in diagnosis. New-onset valvular disease and a stroke in an otherwise healthy young patient should always prompt proper investigation. This case highlights several complications caused by septic emboli of undiagnosed and untreated endocarditis.Mercury (Hg) pollution is a global threat to human and environmental health because of its toxicity, mobility and long-term persistence. Although costly engineering-based technologies can be used to treat heavily Hg-contaminated areas, they are not suitable for decontaminating agricultural or extensively-polluted soils. Emerging phyto- and bioremediation strategies for decontaminating Hg-polluted soils generally involve low investment, simple operation, and in situ application, and they are less destructive for the ecosystem. Current understanding of the uptake, translocation and sequestration of Hg in plants is reviewed to highlight new avenues for exploration in phytoremediation research, and different phytoremediation strategies (phytostabilization, phytoextraction and phytovolatilization) are discussed. Research aimed at identifying suitable plant species and associated-microorganisms for use in phytoremediation of Hg-contaminated soils is also surveyed. Investigation into the potential use of transgenic plants in Hg-phytoremediation is described. Recent research on exploiting the beneficial interactions between plants and microorganisms (bacteria and fungi) that are Hg-resistant and secrete plant growth promoting compounds is reviewed. We highlight areas where more research is required into the effective use of phytoremediation on Hg-contaminated sites, and conclude that the approaches it offers provide considerable potential for the future.Functional mineral water and related products are popular in some Asian countries as health drinks and, recently, have been employed in agricultural crop production as well as pest control. This study aimed to investigate the survival of mosquito vectors exposed to plant-derived functional mineral water produced by terahertz technology. The terahertz-based functional mineral water used in the current study not only decreased the hatching of Culex quinquefasciatus (Say) larvae but also showed concentration-dependent toxicity to the 3rd instar larvae and pupae of the three mosquito species tested. Aedes albopictus (Skuse) and Cx. quinquefasciatus pupae were more susceptible to terahertz-based functional mineral water than the larval stage, as indicated by their lower LC50. Lower concentrations ( less then 100 ppm) of terahertz-based functional mineral water were not lethal to the pupae; however, these low concentrations still resulted in a reduced adult emergence. Although terahertz-based functional mineral water did not significantly affect Aedes aegypti (Linnaeus) hatching, it could potentially be used for vector control at the larvae and pupae stages. The larvicidal and pupicidal activity of diluted terahertz-based functional mineral water gradually diminished after 24 h, indicating that it is a biodegradable and eco-friendly bioinsecticide. However, as the terahertz-based functional mineral water is also toxic to larvivorous predatory-copepods, it should not be utilized in aquatic environments where predatory-based mosquito control programs are employed.

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