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teria and C. albicans fungi, which indicates a violation of the microbiocenosis due to reduced mucosal immunity. Mucosal immunity of the oral cavity in children with mucoviscidosis is characterized by a 1.5-fold decrease in lysozyme activity and the level of secretory IgA in the saliva of children.
Restoration of the masticatory function is one of the key elements in the comprehensive rehabilitation for patients with acute cerebrovascular disorders (ACVD) of various degrees, as their consequences may include an impaired coordinated action of the neuromuscular system, and the dentoalveolar system in particular. In this context, the clinical presentation of stroke is characterized by motor and sensory deficiencies, which can eventually lead to dysfunction of the masticatory muscles, tongue, lips, soft palate and pharynx. The bilateral difference between such disorders, manifested by the discrepancy in the muscle mass and kinematic characteristics, is the peculiarity of this phenomenon.
The aim of the research was to examine the features of articulatory activity in the mandible during chewing at the stages of orthopedic rehabilitation in patients with complicated acute cerebrovascular disorder with the neurological deficit by hemitype during the prosthetics with removable orthopedic appliances.
The sst significant differences in videokinesiography between the representatives of the second group (ACVD) and the control group on the 30th day of observation were a relatively smaller amplitude of vertical movements (p =.0001) and smaller amplitude of horizontal movements (p =.0000). learn more Thus, the amplitude of vertical and horizontal movements of the mandible, in our opinion, can be considered as a reliable marker of the functional activity of the dentoalveolar system in patients with a complicated course.
Breastfeeding is the primal form of feeding new-borns and has multiple benefits to mothers and children. However, often introduction of infant formula is necessary due to breastfeeding cessation or infant's inability to thrive on human milk.
The aim of the study was to analyse elementary lactation problems in the first days postpartum leading up to feeding new-borns with infant formula.
The diagnostic survey that consisted of 28 questions was performed on a group of 194 patients staying at the Obstetrics and New-borns Department of the Duchess Anna Mazowiecka Clinical Hospital in Warsaw from September until December 2018.
Most of respondents that gave birth naturally didn't give the infant formula after birth (62.4%, n=58/93), whereas patients giving birth by caesarean section 69.0% (n=69/100) fed infant formula to new-borns after birth. The administration of infant formula significantly depended on the mode of delivery (p<0.01) and on whether the baby had suckled on the first contact (p<0.01). Moreover, patients with prepregnancy diabetes (81.8%, n=9/11, p<0.05) and obesity (76.2%, n=16/21, p<0.05) were more likely to give children infant formula.
Feeding with infant formula is more frequent after caesarean section and when there is coexistence of diseases with pregnancy. Suckling the breast during the first skin-to-skin contact has a positive effect on the duration of lactation.
Feeding with infant formula is more frequent after caesarean section and when there is coexistence of diseases with pregnancy. Suckling the breast during the first skin-to-skin contact has a positive effect on the duration of lactation.
Ischemic stroke is the main cause of permanent disability in adult patients. No commonly accepted method were discovered to predict stroke before the first symptoms. Activation of matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMP) and S100B protein may be observe in patients with symptomatic carotid artery stenosis. Hemorrhagic transformation of ischemic stroke may be associated with changes in MMP, TIMP and S100B.
The aim of this study was to determine if MMP-9, TIMP-1 and S-100B protein may markers of forthcoming ischemic stroke in patients undergoing carotid endarterectomy.
Blood samples were taken and an analysis of circulating proteins (MMP-9, TIMP-1, S100B) 73 subsequent patients with carotid artery stenosis ≥70% (33 asymptomatic and 40 symptomatic), who were referred for potential revascularization.
A statistically significant difference was found between MMP- 9 levels in patients with ischemic stroke compared to patients with asymptomatic carotid stenosis after endarterectomy. Also, average TIMP-1 levels in patients with ischemic stroke and stenosis ≥70% were statistically significantly higher than the average levels in patients after endarterectomy. In terms of S-100B, a higher mean value was observed in patients with stroke than in endarterectomy group. No statistical differences were found in the levels of that proteins in the hemorrhagic transformation of ischemic stroke.
Increased levels of MMP-9, TIMP-1 and S-100B in patients with ischemic stroke compared to patients with asymptomatic carotid stenosis after endarterectomy showed that abovementioned proteins may be a good predictive factor of ischemic stroke in patients undergoing carotid endarterectomy.
Increased levels of MMP-9, TIMP-1 and S-100B in patients with ischemic stroke compared to patients with asymptomatic carotid stenosis after endarterectomy showed that abovementioned proteins may be a good predictive factor of ischemic stroke in patients undergoing carotid endarterectomy.
An improving quality of life of a patient seems to be the primary goal of contemporary medicine facing the controversies arising over the duration of persistent therapy, on the one hand, and mounting costs of health care, on the other.
The aim of the study was to assess the applicability of the SF-36 (Short Form Health Survey) quality-of-life scale to the evaluation of patients with lower-extremity atherosclerosis and to find a link with the new composite endpoint of the study which the quality of life predisposes to.
The patients operated on for lower-extremity atherosclerosis (y-graft) in one centre in the years 1999-2004 were invited to take part in the study. 64 out of 172 patients joined the study. The study participants were assessed for the quality of life, distance intermittent claudication and lower-extremity pulse presence. Information was also collected on their past medical history and life style. The works of the study group undertaken in 2021 thanks to cooperation with the Ministry of Digitiating patients who die within 10 years from the surgery and those with an over-10 survival are primarily emotional well-being related issues.
The spreading pandemic, successive waves and increasingly inefficient hospital care system contributed to the analysis and inclusion of lung ultrasonography (LUS) in the COVID-19 diagnostic process, which is faster, cheaper, more available and safer method for patients. It is also the method of choice for pregnant women and children.
The aim of this study was to analyze the effectiveness of lung ultrasound in the diagnostic process, its predictive value and its comparison with computed tomography (CT) of the chest.
A literature review was conducted with keyword in the title and abstracts in the Pubmed National Library of Medicine database.
Twenty papers were reviewed which showed a high consistency in CT and ultrasound image evaluation, particularly in the inferolateral and posterior lung areas. The association between LUS and CT images with disease severity has also been demonstrated, which translates into the predictive value of these studies related to hospitalization, use of invasive and non-invasive mechanical ventilation, and mortality in COVID-19 patients. An association between the stage of disease severity assessed by LUS and elevated levels of inflammatory markers were revealed. In addition, lung ultrasound showed high sensitivity in the early stages of the disease.
Ultrasound performed by appropriately trained staff is a good diagnostic and prognostic tool in the Hospital Emergency Department and Intensive Care Unit. Nevertheless, due to the subjectivity and technical limitations of this study, this method needs further research.
Ultrasound performed by appropriately trained staff is a good diagnostic and prognostic tool in the Hospital Emergency Department and Intensive Care Unit. Nevertheless, due to the subjectivity and technical limitations of this study, this method needs further research.
The disease caused by the SARS-CoV-2 (COVID-19) is currently one of the leading causes of hospitalization and death. It has been shown that early assessment of selected laboratory parameters blood count parameters, concentration of protein C (CRP), D-dimers, ferritin, cardiac troponins or interleukin 6 (IL-6) in patients hospitalized due to COVID- 19 may facilitate predicting its severe course. However, the relationship between uric acid (UA) levels and the prognosis in COVID-19 is unclear.
The aim of the study was to determine the relationship between hyperuricemia and the course of SARS-CoV-2 infection and the prognosis of patients hospitalized due to COVID-19, taking into account concomitant cardiovascular diseases.
Retrospective analysis of consecutive COVID- 19 patients admitted to the hospital, whose parameters of inflammation were measured on admission C-reactive protein (hs-CRP), procalcitonin, interleukin-6, d-dimers, estimated glomerular filtration rate (eGFR) and UA concentration. The clinicae prognosis in patients with COVID-19. The presence of overt cardiovascular diseases is the strongest risk factor for death in the course of SARS-CoV-2 infection. Higher concentration of UA is associated with the presence of cardiovascular diseases, however, it is not an independent factor affecting the course and mortality in COVID-19.
The diagnosis of hyperuricemia on admission to hospital is not associated with a worse prognosis in patients with COVID-19. The presence of overt cardiovascular diseases is the strongest risk factor for death in the course of SARS-CoV-2 infection. Higher concentration of UA is associated with the presence of cardiovascular diseases, however, it is not an independent factor affecting the course and mortality in COVID-19.
Cell-free DNA (cfDNA) is released into the circulation after apoptosis, necrosis, and active secretion from cells. In a healthy individual, cfDNA is present in small amounts, has a short half-life, and is predominantly derived from circulating hematopoietic cells. The composition and quantity of cfDNA dramatically changes during pathological conditions. Indeed, several studies reported elevated cfDNA concentration as a potential noninvasive biomarker in many diseases.
The aim of the study was evaluation of the circulating cell-free DNA in patients with severe Covid-19 in comparison with patients with hospitalised community-acquired pneumonia (with and without hyperglycemia and type 2 diabetes mellitus) to determine the specificity, sensitivity and cutoff value of cfDNA for each nosology.
The studies were carried out on the basis of city and regional hospitals in the Luhansk region between 2015 to 2021. Were examined in the study 28 patients with a positive diagnosis of COVID-19 according to PCR analysis (14 women and 14 men), 60 patients with community- acquired pneumonia (CAP) (30 women and 30 men), 101 patients with community-acquired pneumonia and hyperglicemia (CAP+HH) (44 women and 57 men), 70 patients with type 2 diabetes mellitus (T2DM) (37 women and 33 men), 42 patients with community-acquired pneumonia in combination with type 2 diabetes mellitus (CAP+T2DM) (27 women and 15 men).
