Elmorecramer3027
As video chatting has emerged as a leading form of communication for work, education, and socialization during the COVID-19 pandemic, it is important to investigate the association between video chatting and appearance satisfaction.
Participants included women from the United States (n = 438; age M = 31.3, SD = 12.71) who completed measures examining their use of video chatting services, self-objectification, video chatting appearance comparison, and appearance satisfaction.
The total time spent on video chatting services was not associated with appearance satisfaction; however, self-objectification moderated the relationship between total hours of video chatting and appearance satisfaction. In addition, participants who engaged in more video chatting appearance comparisons reported lower face and body satisfaction. Furthermore, video chatting appearance comparison was associated with more frequent usage of certain Zoom features, such as the "touch up my appearance" feature, and more time spent looking at oneself on video calls. Finally, those who spent more time engaged with their families over video chatting services reported greater face and body satisfaction.
The results of the current study demonstrate that time spent video chatting is not predictive of appearance satisfaction, but that self-objectification can exacerbate these associations.
The results of the current study demonstrate that time spent video chatting is not predictive of appearance satisfaction, but that self-objectification can exacerbate these associations.The Life Events Checklist for DSM-5 (LEC-5) is a comprehensive screening instrument used to detect exposure to a range of potentially traumatic events. Despite its widespread use, research assessing the psychometric properties of scores on the LEC-5-and trauma exposure more broadly-is scarce. Using a large sample of undergraduate students (N = 1,013), we sought to evaluate the reliability of trauma exposure reporting on the LEC-5 across 8- (N = 379) and 12-week (N = 343) intervals. Reliability estimates were examined for trauma exposure type (e.g., experiencing, witnessing), traumatic event type (e.g., sexual assault), and index trauma (i.e., "worst event") reporting. Reliability was more stable for events that were directly experienced, intraclass correlation coefficients (ICCs) = .62-64, than events that were witnessed, ICCs = .47-.52, or learned about, ICCs = .48-.53. Test-retest agreement was fair to good for reports of sexual assault, physical assault, transportation accidents, natural disasters, and other sexual experiences, κs = .49-.72, but only when individuals directly experienced these events. By contrast, across both assessment intervals, the agreement was attenuated, all κs less then .40, for events that individuals witnessed or learned about regardless of event type. For index events, only sexual assault and sudden accidental or violent deaths were consistently reported with a fair or better agreement, κs = .42-.64. These findings suggest that reliable trauma reporting varies largely based on the nature of the traumatic event, yielding important implications for the assessment of DSM-5 Criterion A and posttraumatic stress disorder.Hematopoietic stem and progenitor cells (HSPC) can differentiate into all hematopoietic lineages to support hematopoiesis. Cells from the myeloid and lymphoid lineages fulfill distinct functions with specific shapes and intra-cellular architectures. The role of cytokines in the regulation of HSPC differentiation has been intensively studied but our understanding of the potential contribution of inner cell architecture is relatively poor. Here, we show that large invaginations are generated by microtubule constraints on the swelling nucleus of human HSPC during early commitment toward the myeloid lineage. These invaginations are associated with a local reduction of lamin B density, local loss of heterochromatin H3K9me3 and H3K27me3 marks, and changes in expression of specific hematopoietic genes. This establishes the role of microtubules in defining the unique lobulated nuclear shape observed in myeloid progenitor cells and suggests that this shape is important to establish the gene expression profile specific to this hematopoietic lineage. It opens new perspectives on the implications of microtubule-generated forces, in the early commitment to the myeloid lineage.The paraphyletic diatom genus Nitzschia comprises over 1000 morphologically distinct pennate taxa, known from the benthos and plankton of freshwater, brackish, and marine environments. The principal diagnostic characters for delimitation of Nitzschia species include valve shape, the position and structure of the raphe, presence/absence and shape of the proximal raphe endings and terminal raphe fissures, areola structure, and specific morphometric features such as cell size, and stria and fibula density. In this study, we isolated 12 diatom strains into culture from samples collected at the surface or greater depths of the southeastern Adriatic Sea. Morphological analyses included LM, SEM, and TEM observations, which, along with specific morphometric features, allowed us to distinguish three new Nitzschia species. These findings were congruent with the results of phylogenetic analyses performed on nuclear-encoded SSU (18S) rDNA and chloroplast-encoded rbcL and psbC genes. One of the new species (Nitzschia dalmatica sp. nov.) formed a lineage within a clade of Bacillariaceae containing members of the Nitzschia sect. Dubiae, which was sister to Psammodictyon. A second lineage was part of a novel clade that is significantly distinct from other Nitzschia species sequenced so far and includes Nitzschia adhaerens sp. nov. and N. cf. adhaerens. A further new species was found, Nitzschia inordinata sp. nov., which appeared as the sister group to the N. adhaerens clade and the conopeoid Nitzschia species in our phylogenetic trees. Our findings contribute to the overall diversity of genus Nitzschia, especially in identifying some deep branches within the Bacillariaceae, and highlight under-scoring of this genus in marine plankton.For more than a century, the need for energy has exerted high demand on oil production and led to significant negative impacts on soil and water resources. The aim of our work was to assess such impacts on the ecological functions of oil-contaminated soils in West Siberia of Russia. The total petroleum hydrocarbons (PHC) content in contaminated soils varied between 3.7 and 390 g kg-1 . Although peat had the ability to absorb some PHC, excess oil migrated in soil both downward and laterally. Catalase activity, soil respiration activity (basal respiration [BR], microbial biomass carbon [Cmic], and specific respiration activity [qCO2 ]), and Enchytraeus albidus survival and reproduction rates showed significant negative correlations with PHC concentrations, and thus they can be used as guides for establishing acceptable PHC limits in peat soils. Based on the Logit model, the concentration of PHC in peat soil that corresponds to ∼20% reduction on functions (worm reproduction, catalase activity, and basal respiration) is about 40-50 g kg-1 . The concentrations of PHC that will result in 80% functional reductions (i.e., near-complete loss on functional activities) are worm production (177 g kg-1 ), catalase activity (123 g kg-1 ), and basal respiration (311 g kg-1 ). This study provides quantitative understanding of the ecological impact of PHC contamination on peat soils and thus helps to establish science-based guidelines for the protection of ecological functions and services of peatland soils.
Rheumatoid arthritis (RA) is associated with increased risk of infections. Screening for oral (dental and/or sinus) infection could be proposed before biologic disease-modifying antirheumatic drugs (bDMARDs) initiation but is not systematically recommended. The aim of our study was to assess the prevalence of oral infection in RA patients requiring bDMARDs.
This was a monocentric retrospective study. We included patients with RA and active disease requiring bDMARDs. Dental infection and sinusitis were assessed by a stomatologist and otorhinolaryngologist after clinical, panoramic dental X-ray and sinus CT evaluation. Factors associated with oral infections were analysed in uni- and multivariate models, estimating odds ratios (ORs) and 95% confidence intervals (CIs).
We included 223 RA patients (79.4% women, mean disease duration 8.9±8.6years). The mean age was 54.4±10.9years and mean Disease Activity Score in 28 joints 5.5±2.6. Systematic dental screening revealed infection requiring treatment before bDMARDs initiation in 46 (20.9%) patients. Sinusitis was diagnosed by the otorhinolaryngologist in 33 (14.8%) patients. Among the 223 patients, 69 (30.9%) had dental and/or sinus infection. On univariate analysis, active smoking was associated with increased probability of oral infection (OR=2.16 [95% CI 1.02-4.57], P=.038) and methotrexate with reduced probability (OR=0.43 [95% CI 0.23-0.81], P=.006). On multivariate analysis, no RA variables were associated with oral infection.
In our study, asymptomatic oral infection was confirmed in one third of RA patients.
In our study, asymptomatic oral infection was confirmed in one third of RA patients.
We present a first-principles molecular dynamics (MD) simulation and expound upon a mechanism of oxygen depletion hypothesis to explain the mitigation of normal tissue injury observed in ultra-high-dose-rate (UHDR) FLASH radiotherapy.
We simulated damage to a segment of DNA (also representing other biomolecules such as RNA and proteins) in a simulation box filled with
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molecules. Attoseconds physical interactions (ionizations, electronic, and vibrational excitations) were simulated by using the Monte Carlo track structure code Geant4-DNA. Immediately after ionization, ab initio Car-Parrinello molecular dynamics (CPMD) simulation was used to identify which
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molecules surrounding the DNA molecule were converted into reactive oxygen species (ROS). Subsequently, the femto- to nanosecond reactions of ROS were simulated by usinge would be reduced in an environment with physoxic oxygen levels. Hence irradiation at UHDRs would be more effective for sparing physoxic normal tissues but not tumors containing regions of hypoxia. At much higher levels of oxygen (e.g., >10-15%), oxygen depletion by UHDRs may not be sufficient for tissue sparing.
10-15%), oxygen depletion by UHDRs may not be sufficient for tissue sparing.Acetylcholine acts as a neurotransmitter/neuromodulator of many central nervous system processes such as learning and memory, attention, motor control, and sensory processing. The present study describes the spatial distribution of cholinergic neurons throughout the brain of the weakly electric fish, Apteronotus leptorhynchus, using in situ hybridization of choline acetyltransferase mRNA. Distinct groups of cholinergic cells were observed in the telencephalon, diencephalon, mesencephalon, and hindbrain. These included cholinergic cell groups typically identified in other vertebrate brains, for example, motor neurons. Using both in vitro and ex vivo neuronal tracing methods, we identified two new cholinergic connections leading to novel hypotheses on their functional significance. Projections to the nucleus praeeminentialis (nP) arise from isthmic nuclei, possibly including the nucleus lateralis valvulae (nLV) and the isthmic nucleus (nI). The nP is a central component of all electrosensory feedback pathways to the electrosensory lateral line lobe (ELL).
