Ehlerscohen3572

Patients who informed their employer about an MS diagnosis significantly more often received support from the company, were professionally active for longer, and less likely to experience a decrease in income. Membership of the MSS were dominated by patients with progressive variants of the disease and advanced disability.

The disease variant and, to a lesser extent, the place of residence, affected the socio-economic aspects of MS. It might be advantageous for the patient to disclose information about MS diagnosis to the employer.

The disease variant and, to a lesser extent, the place of residence, affected the socio-economic aspects of MS. Epacadostat cell line It might be advantageous for the patient to disclose information about MS diagnosis to the employer.

The aim of the study was to perform translation and cultural adaptation, as well as to assess the validity and reliability of the Polish version of the Neonatal Extent of Work Rationing Instrument (NEWRI) questionnaire for evaluating care rationing in neonatal intensive care units (NICUs) in Poland.

Participants were prospectively recruited at the University Clinical Hospital in Wroclaw, Poland, and the study conducted from January 2018 - June 2018. The adaptation process involved translation of survey items following the guidelines for cross-cultural translation and evaluation of psychometric properties, as well as an assessment of construct validity, reliability, and internal consistency of the NEWRI using Cronbach's alpha.

113 professionally active nurses (n=90) and midwives (n=23) were enrolled in the study. Cronbach's alpha for the entire instrument was 0.982. Results for subscales life support and technology-oriented nursing care - Cronbach's alpha - 0.95, parental support and teaching and infant comfort care - 0.95, patient surveillance - 0.92, care coordination and discharge planning - 0.79. All items of the questionnaire were found to have a positive discriminatory power.

The present findings indicate a high level of reliability and validity of the translated questionnaire, fully comparable to that of the original. The questionnaire can be used for evaluating care rationing in NICUs.

The present findings indicate a high level of reliability and validity of the translated questionnaire, fully comparable to that of the original. The questionnaire can be used for evaluating care rationing in NICUs.

Asthma, a chronic lung disease, is a major health challenge worldwide with increased addressability to health services. There are different asthma phenotypes, which have different evolution and can be specifically tracked. The measurement of fractional expired nitric oxide (FeNo) with different devices reflects the eosinophilic inflammation of the airways, and can be used to evaluate the allergic phenotype and predict the treatment responses. The new GINA (Global Initiative for Asthma) guideline recommends FeNO monitoring to assess adherence to cortisone treatment in high doses before prescribing biological treatment, and as a means of monitoring the decrease in oral corticosteroid treatment.

The aim of the study is to analyze the applicability of FeNO in monitoring response to therapy.

An observational study was carried out on 129 subjects with a previously established diagnosis of asthma. The research was based on the determination of FeNO with NObreath. Those with intermediate FeNO received a low dose of inhaled corticosteroids in mono/dual therapy, those with increased FeNO received medium ICS mono/dual therapy. FeNO testing, its values and doses of ICS were below the the ATS / ERS guidelines.

FeNO reduction is strictly dependent on the cortisone dose. Applying the dual therapy from the beginning does not bring additional benefits in comparison with cortisone in monotherapy, in terms of FeNO value.

Recommendations that include FeNO testing can help monitor response to treatment.

Recommendations that include FeNO testing can help monitor response to treatment.

Increased serum cholesterol levels constitute one of the main risk factors for cardiovascular diseases. Statins are a major method for reducing the levels which also lower the risk of cardiovascular events. However, these valuable drugs cannot be used in all patients who need them due to contraindications and intolerance. In such cases, help can be sought from nutraceutics that reduce the serum cholesterol concentration. Since there are numerous products of this type available at drugstores, registered as supplements, there seems to be a need to demonstrate their effectiveness in preventing cardiovascular diseases induced by atherosclerosis. In literature, increasingly more attention is drawn to red yeast rice, Armolipid, berberine and bergamot.

This article presents knowledge about these nutraceutics based on clinical studies and expert statements relating to their use. The results of clinical studies and metaanalyses have shown that nutraceutics with cholesterol lowering properties, red yeast rice and Armolipid are the most favourable for reducing cardiovascular events. However, the evidence of benefits of berberine and bergamot is not so conclusive.

Red yeast rice products and Armolipid may be used as an alternative treatment in statin intolerant patients, especially in combination with ezetimibe. These nutraceutics can be also considered, as an adjunct to diet therapy in primary prevention of cardiovascular diseases in patients with mild and moderate hypercholesterolaemia. The opinion of experts on berberine and bergamot is ambiguous.

Red yeast rice products and Armolipid may be used as an alternative treatment in statin intolerant patients, especially in combination with ezetimibe. These nutraceutics can be also considered, as an adjunct to diet therapy in primary prevention of cardiovascular diseases in patients with mild and moderate hypercholesterolaemia. The opinion of experts on berberine and bergamot is ambiguous.

Mycotoxins - secondary mould metabolites with undesirable effects for humans - are common in the environment. These toxins are mainly produced by fungi of the genera Penicilium, Aspergillus and Fusarium.

The aim of this study was to evaluate the applicability of various sources of antioxidants (blueberries lyophilisate, cranberries lyophilisate and cinnamon powder), at 5 different concentrations (3%, 5%, 10%, 20%, 30%), to inhibit the formation of mycotoxins during the storage of cereal products. Analysed cereal samples included selected cereal grains, bran and cereal products intended for consumption by children.

The results showed that supplementation of oat brans with the highest concentrations of blueberry lyophilisate resulted in a significant decrease in the mycotoxins levels; specifically 20% concentration reduced the level of HT-2 toxin by 10.7% in one sample, while 30% concentration reduced it by 9.4% and 17.4% in 2 other samples. A similar result was measured for oat bran samples supplemented with the cranberry lyophilisate specifically, 20% concentration significantly reduced the level of HT-2 toxin by 10.