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Purpose To evaluate the sensitivity and specificity of the near-infrared light transillumination caries detection method by using DEXIS CariVu (DCV) for imaging of interproximal primary molar surfaces (IPMS).Conclusion The use of DCV as a stand-alone caries detection method for IPMS is limited.Purpose To evaluate reasons pediatric dental patients missed appointments associated with general anesthesia (GA) or monitored anesthesia care (MAC).Conclusion Significant differences were found between patients who failed their appointments and those who kept them.Purpose This cross-sectional study evaluated knowledge, practices, and beliefs of Ohio dentists treating school-aged children regarding school absenteeism in relation to compliance with dental appointments.Conclusion Dentists acknowledged that school absences and school policy affected parental choices regarding dental visits, with PDs consistently stating a greater effect than GDs.Purpose To evaluate body mass index (BMI) - early childhood caries (ECC) relationships with various BMI expressions.Conclusion BMI-ECC associations might be nonlinear; being underweight could be a male ECC risk factor. Studies should include extreme BMI values without collapsing BMI categories.Purpose To evaluate the use of lingual frenotomy assessment tools and the anatomical features most commonly used by dentists and otolaryngologists to determine if a frenotomy was indicated.Conclusions Many practitioners believe frenotomies for ankyloglossia are indicated when there is a functional impairment and an anatomical component. This study suggests that the general appearance of the tongue when lifted is the most common anatomical feature used for assessing the need for a frenotomy.Purpose The purpose of this study was to evaluate the effect of acrylated hydroxyazobenzene (AHA) copolymers in a composite-resin matrix on Streptococcus mutans (SM) biofilms. Methods The AHA was synthesized and polymerized within a bisphenol A-glycidyl methacrylate and triethylene glycol dimethacrylate (bisGMATEGDMA) matrix while bisGMATEGDMA discs served as controls. The cytotoxicity of AHA was determined using a cell viability assay. Sucrose-dependent SM biofilms were grown on the AHA and control substrates. At 24 hours and after mechanical toothbrushing (equivalent to six months), the number of live SM was quantified on the substrates and in the surrounding media. Microscopic images of the substrates were captured after live-dead staining. Results The AHA substrates were as biocompatible as bisGMA TEGDMA substrates. The microscopic images and quantification demonstrated no live SM on the AHA substrates and in the surrounding media as compared to the controls. The inhibitory efficacy of AHA substrates on SM biofilm was intact even after mechanical toothbrushing. Conclusions Acrylated hydroxyazobenzene in a composite-resin matrix completely inhibits SM proliferation growth and demonstrates a zone of SM inhibition. The antibacterial propertyof AHA could be harnessed for caries prevention in high caries-risk children by incorporating AHA into the restorative and sealant materials.Purpose The purpose of this pilot study was to evaluate the safety of nitrous oxide (N₂O) during dental procedures in pediatric patients with sickle cell disease (SCD). Methods Patients three to 15 years of age received N₂O with oxygen (N₂OO₂) during their dental procedure in a university pediatric dental clinic between March 2019 and December 2020. Blood oxygen levels were monitored via pulse oximetry throughout the visit. Caregivers received a follow-up call to assess for postoperative complications. Results Twenty-three patients were enrolled. The duration of N₂O sedation was 20 to 50 minutes. Oxygenation levels during (P less then 0.001) and after (P=0.004) the procedure were higher than for baseline. No adverse effects were reported in the three days after N₂O use. Conclusions Following dental guidelines for sedation, treatment with up to a 5050 mixture of nitrous oxide with oxygen increased blood oxygen levels and did not cause postoperative complications in children with sickle cell disease. This is the first formal study confirming the safety of nitrous oxide use in the dental care of SCD patients.Purpose The purpose of this study was to evaluate the progression of incipient approximal caries lesions in permanent teeth of children and adolescents with and without silver diamine fluoride (SDF) application. Methods A retrospective analysis of dental records and radiographs was performed. Baseline and follow-up bitewing radiographs were evaluated and scored using International Caries Classification and Management System (ICCMS) criteria to assess lesion progression. Results A total of 131 lesions from 68 subjects (mean age equals 9.6 years) were evaluated radiographically and followed for up to 41 months (mean time equals 13.61±6.8 months); 23.6 percent of lesions in the SDF group progressed compared to 38.1 percent in the control group (P less then 0.001). On average, lesions in the control group increased more per month compared to the study group (P less then 0.001). The odds of lesion progression in the control group were 2.76 times the odds of progression in the study group. There was a statistically significant difference in lesion progression based on application method; lesions where SDF was applied with Superfloss progressed more per month, on average, versus microbrush application. Conclusions Silver diamine fluoride may be an effective therapy to slow caries progression of incipient approximal lesions in permanent teeth in high caries-risk populations. Future studies are needed to detect differences in application methods.Purpose Dental rehabilitation under general anesthesia (DRGA) is performed increasingly by pediatric dentists. Follow-up visits and ongoing recall attendance are shown to be low post-DRGA. There is currently no guideline or published study on optimal DRGA follow-up timing recommendations. A quality improvement initiative was performed at Children's Dental Center of Children's Wisconsin to increase the rate of follow-up post-DRGA. The purpose of this study was to evaluate changes in follow-up compliance after implementing a two-week visit recommendation instead of a six-week interval for dental rehabilitation under general anesthesia follow-up. Methods The DRGA follow-up visit recommendation was changed from six weeks to two weeks postsurgery. Attendance rates for recall exams were evaluated before and after implementation with 17 months follow-up (n equals 544). Attendance was then compared by age, special health care needs, foster care status, and caries recurrence. Results The intervention improved compliance with DRGA follow-up for all ages (P less then 0.001) and six-month recall visits for ages zero to five (83.3 percent of cases, P=0.001). Patients were more likely to return for any visit within 17 months in the two-week follow-up group compared to the six-week group (P=0.002). There was no difference in caries recurrence requiring treatment between the two follow-up timing groups (P=0.86). selleckchem Conclusion Changing the dental rehabilitation under general anesthesia follow-up from six weeks to two weeks improved compliance through six months and decreased the overall number of patients lost to follow-up.Purpose (1) Implementation of teledentistry in a private pediatric practice during COVID-19 pandemic, (2) Evaluate dental care that was assessed and managed during the COVID-19 pandemic. Methods Urgent dental care provided during the recommended deferment of elective dentistry (3/16/20-5/17/20) was documented. Encounters were documented by type and management (conventional vs. teledentistry). Results were summarized using descriptive statistics. Associations were compared with Chi-squared or Fisher's exact test. Results There were 137 emergency patient encounters during the study period. The types were orthodontics (32 percent), caries (22 percent), eruption concerns (18 percent), trauma (16 percent), "other" (12 percent) (i.e., ankyloglossia, aphthous ulcers). Almost half (48 percent) were managed with teledentistry. The highest utilization of conventional dentistry was caries (70 percent), and for teledentistry was "Other" (75 percent) and eruption concerns (60 percent). Conclusion Nearly half of emergency encounters in this sample were managed with teledentistry. Teledentistry was a necessary modality of care during the beginning of the COVID-19 pandemic and has uses and implications beyond the triage of acute dental emergencies.Purpose The purpose of this study was to compare the effectiveness of intranasal dexmedetomidine (DEX), oral midazolam (MID), and oral midazolam combined with oral hydroxyzine (MIDHYD) with nitrous oxide when used for sedation during pediatric dental procedures. Methods The charts of 146 patients who underwent dental procedures using moderate sedation with DEX, MID, or MIDHYD, all with nitrous oxide, from January 2014 to December 2019, were reviewed retrospectively. Sedations were evaluated for effectiveness based on sedation level and behavior using a modified University of Michigan Sedation Scale and behavior using the American Academy of Pediatric Dentistry sedation behavior scale. Procedures planned and completed were evaluated for each sedation regimen. Results Overall, the effectiveness was not statistically different between sedation regimens (P=0.71). More stainless steel crowns were planned and completed with DEX, more resins were planned and completed with MIDHYD, and more extractions were planned and completed with MID. The onset of action and working time were found to be statistically significant between sedation regimens; DEX had the longest working time. Conclusions This retrospective study found that intranasal dexmedetomidine with nitrous oxide showed no statistical difference in effectiveness, compared with oral midazolam or oral midazolam combined with oral hydroxyzine and nitrous oxide, in moderate sedation for pediatric dental procedures. The majority of stimulating time-consuming procedures were completed in the DEX sedation regimen.Purpose The purpose of this study was to describe the prevalence of radiographically identifiable developmental dental anomalies (DDA) in a university-based pediatric dental clinic and to assess for associations between DDA and health status. Methods Retrospective data, obtained from the electronic dental records of a three-year pediatric patient cohort, were evaluated by two trained and calibrated examiners. Strict inclusion/ exclusion criteria were applied. A validated image quality grading system was used for radiograph assessment, and the physical status classification of the American Academy of Anesthesiology was utilized. A chi-square test and bivariate logistic regression were used for statistical analysis. The inter- and intraexaminer reliability was assessed using Cohen's Kappa. Results A total of 1,478 subjects (69 percent medically healthy) were enrolled. DDA were identified in 25 percent of the subjects, with hyperdontia, hypodontia, and microdontia being more common. A statistically significant association was found between the presence of DDA and health status (P less then 0.001) and between DDA and asthma (P=0.035). Patients with systemic disturbances showed 2.12 times greater odds of having DDA (P less then 0.001, 95 percent confidence interval equals 1.7-2.7). Conclusions The prevalence of developmental dental anomalies was high, with one in four patients affected. DDA in number were the most common. Patients with systemic disturbances had greater odds of having DDA.

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