Dominguezroed3744
The outbreak of COVID-19 undoubtedly aggravated the pressure and workload of nurses' work, which may bring new challenges to nurses' work engagement. This study aims to explore the factors of nurses' work engagement, and it may provide targeted references for clinical intervention. Convenience sampling was used, and 689 nurses from Hebei and Guangxi Province in China were investigated. The results indicated that both perceived organizational support and psychological safety have direct positive impacts on nurses' work engagement, and psychological safety mediates the relationship between perceived organizational support and work engagement. These findings provide new ideas to help nursing managers better understand how to improve work engagement.There is limited evidence on the association between different dimensions of socioeconomic status and mental health on adolescents in developing nations. Proteasome inhibitor The aim of this study was to examine this association among adolescents in East China. A school-based study that recruited 6902 adolescents aged 13 to 18 years was conducted in Suzhou, Hefei and Hangzhou. Multiple of indicators of socioeconomic status and mental health in adolescents were examined. Results revealed that girls showed significantly higher score of the global severity index, obsessive-compulsive, depression, anxiety, hostility, and phobic anxiety symptoms than boys. As expected, there was a slightly negative correlation between different dimensions of socioeconomic status to different domains of mental health problems (r ranged from -0.044 to 0.124). Furthermore, we found that maternal education and occupation were significantly associated with mental health for both boys and girls, while subjective socioeconomic status only was significantly associated with girls. In conclusion, adolescents in families with socioeconomic disadvantage, in the form of lower educational level and occupational prestige of mothers, had greater risk of mental health problem. Meanwhile, higher subjective socioeconomic status positively affects the mental health of female adolescents.
Population-level estimates of the median intracerebral hemorrhage (ICH) volume would allow for the evaluation of clinical trial external validity and determination of temporal trends. We previously reported the median ICH volume in 1988. However, differences in risk factor management, neuroimaging, and demographics may have affected ICH volumes. The goal of this study is to determine the median volume of ICH within a population-based cross-sectional study, including whether it has changed over time.
The Genetic and Environmental Risk Factors for Hemorrhagic Stroke study was a population-based study of ICH among residents of the Greater Cincinnati/Northern Kentucky region from 2008 through 2012. This study utilizes those data and compares with ICH cases from the same region in 1988. Initial computed tomography images of the head were reviewed, and ICH volumes were calculated using consistent methodology.
From 2008 through 2012, we identified 1117 cases of ICH. The median volume of ICH was 14.0 mL and was lower in black (11.6) than in white (15.5) patients. Median volumes of lobar and deep ICH were 28.8 mL and 9.8 mL, respectively. Median ICH volume changed significantly from 1988 to 2008-2012, with age-and-race-adjusted volume decreasing from 18.3 mL to 13.76 mL (p = 0.025).
Median volume of ICH was 13.76 mL, and this should be considered in clinical trial design. Median ICH volume has apparently decreased from 1988 to 2008-2012.
Median volume of ICH was 13.76 mL, and this should be considered in clinical trial design. Median ICH volume has apparently decreased from 1988 to 2008-2012.Background An early trend in the mean age of pubertal onset appears in adolescents, but the association between body fat percentage (BF%) of children and precocious puberty is unclear. The aim of the study was to analyze the association of sexual development with BF% in girls. Methods A total of 407 females were included in this cross-sectional study. BF% was measured by Inbody S10, International Obesity Task Force was used to judge overweight or obesity, and early puberty was defined as a younger age than the median age in each of the pubertal Tanner stages. Logistic regression analysis was used to test relationships between pubertal states and independent variables, including age, weight, waist circumference (WC), type of school, and residency. Results Females with early puberty exhibited higher anthropometry data (such as weight, BMI, BF%) than females with normal maturation (p less then 0.001). Weight, BMI, WC, BF% residency, and school type were related to pubertal state (p less then 0.001). Females with higher BF% were more likely to exhibit early puberty (odds ratio = 1.138, 95% confidence interval = 1.046-1.237). The students who lived in urban areas and studied in public schools had a lower risk of early puberty. Moreover, BF% continuously increased with age in 6- to 9-year-old girls. Conclusions Females with higher BF% may be more likely to exhibit early puberty. In future studies, more research is needed to analyze this mechanism of how BF% influences puberty development.Controversies surrounding the name and how the electronics nose (e-nose) works have been at the center stage since the advent of the technology. Notwithstanding the controversies, the technology has gained popularity in the sensory analysis of dairy foods, because of its rapid results delivery on product aroma profile or pattern, which can be used to assess quality. This review critically evaluated the advances made in the application of the e-nose or artificial sensory system in the dairy industry, focusing on the evaluation of milk, yoghurt and cheese properties, and the trends and prospects of the technology. Most of the e-nose devices applied in the available scientific publications used sensors such as metal oxide semiconductor sensors (MOS), metal-oxide-semiconductor field-effect transistor (MOSFET), conducting polymers composites and quartz microbalance (QMB), and flame ionization detector FID, in a recent study. Though known for aroma sensing, the technology has been applied to evaluate the shelf life or microbial spoilage and to discriminate dairy products based on the volatile profile composition, as determined by the sensors. In most cases, the limitation of the technology is the inability of it to provide information on the nature of constituting compounds, except in gas chromatography and mass spectrometry-based e-nose systems.
Insulin exerts vasculoprotective effects on endothelial cells (ECs) and growth-promoting effects on vascular smooth muscle cells (SMCs) in vitro, and suppresses neointimal growth in vivo. Here we determined the role of ECs and SMCs in the effect of insulin on neointimal growth.
Mice with transgene CreER
under the control of EC-specific Tie2 (Tie2-Cre) or SMC-specific smooth muscle myosin heavy chain promoter/enhancer (SMMHC-Cre) or littermate controls were crossbred with mice carrying a loxP-flanked insulin receptor (IR) gene. After CreER
-loxP-mediated recombination was induced by tamoxifen injection, mice received insulin pellet or sham (control) implantation, and underwent femoral artery wire injury. Femoral arteries were collected for morphological analysis 28 days after wire injury.
Tamoxifen-treated
mice showed lower IR expression in ECs, but not in SMCs, than
mice. Insulin treatment reduced neointimal area after arterial injury in
mice, but had no effect in
mice. Tamoxifen-treated
mice showed lower IR expression in SMCs, but not in ECs, than
mice. Insulin treatment reduced neointimal area in
mice, whereas unexpectedly, it failed to inhibit neointima formation in
mice.
Insulin action in both ECs and SMCs is required for the "anti-restenotic" effect of insulin in vivo.
Insulin action in both ECs and SMCs is required for the "anti-restenotic" effect of insulin in vivo.Detecting signet ring cells on histopathologic images is a critical computer-aided diagnostic task that is highly relevant to cancer grading and patients' survival rates. However, the cells are densely distributed and exhibit diverse and complex visual patterns in the image, together with the commonly observed incomplete annotation issue, posing a significant barrier to accurate detection. In this article, we propose to mitigate the detection difficulty from a model reinforcement point of view. Specifically, we devise a Classification Reinforcement Detection Network (CRDet). It is featured by adding a dedicated Classification Reinforcement Branch (CRB) on top of the architecture of Cascade RCNN. The proposed CRB consists of a context pooling module to perform a more robust feature representation by fully making use of context information, and a feature enhancement classifier to generate a superior feature by leveraging the deconvolution and attention mechanism. With the enhanced feature, the small-sized cell can be better characterized and CRDet enjoys a more accurate signet ring cell identification. We validate our proposal on a large-scale real clinical signet ring cell data set. It is shown that CRDet outperforms several popular convolutional neural network-based object detection models on this particular task.Ankle fractures are common injuries that can result in substantial morbidity in the population. This review discusses the management of closed ankle fractures and outlines the recent evidence and guidelines on perioperative management. In general, a detailed history should be undertaken, followed by examination and imaging of the affected limb. Fixation is based on the AO principles of fracture management that aims towards restoring stability of the joint and reducing the risk of long-term complications. A multidisciplinary approach towards perioperative management is recommended in view of the increasing proportion of aging patients with significant comorbidities.Virtual reality is an immersive experience that has been gaining acceptance in the field of medicine as a tool for reducing patient anxiety. We recently observed the effectiveness of this technology in wide-awake local anaesthesia no tourniquet (WALANT) surgeries. Here we report two cases of patients who used a virtual reality device during hand surgery using the WALANT technique. Both patients reported that the use of VR technology reduced their anxiety and improved their overall experience during surgery. This case report highlights the novel use of virtual reality during hand surgeries where the patients were awake. Based on these two cases, virtual reality may have the potential to reduce anxiety during the perioperative period and enhance a patient's overall experience in WALANT surgeries.
Post-anaesthetic shivering is frequently preceded by a decrease in peripheral blood flow. Perfusion index is a fast non-invasive method to assess peripheral blood flow, thus might be correlated with post-anaesthetic shivering.
To analyse the relationship between preoperative perfusion index and post-anaesthetic shivering in patients undergoing caesarean section with spinal anaesthesia.
In this prospective observational study, preoperative perfusion index measurements were performed on 40 participants who were undergoing elective caesarean section under spinal anaesthesia. Spinal anaesthesia was performed using Lidodex (Lignocaine + Dextrose 5%) at vertebrae L4-L5 or L3-L4 interspace. Shivering was observed until 120 minutes according to the Crossley and Mahajan scale. Statistical analysis was performed to examine the correlation and cut-off of preoperative perfusion index as a predictor for post-anaesthetic shivering.
There was a significant relationship between preoperative perfusion index with the incidence (
= 0.
