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Indeed, industrial technologies with sludge ash as input show high recovery efficiencies (Ashdec® and Leachphos® with 98 and 79%) and lower environmental impacts, whereas Pearl® technology has about 12% recovery efficiency with wastewater as input. After all, struvite emerges as the most recovered product with recent access to the internal market of EU fertilisers and similar growth performance compared to triple-super-phosphate. However, several studies leave open the possibility of introducing loaded adsorbents with P as soil amendments as a new alternative to conventional desorption. Briefly, P recovery should be a compromise between efficiency, environmental impacts, and economic revenues from the final products.Certain font features (e.g., letter width) can change the amount of space occupied by text in published works. Font styles/features are also known to affect reading eye movements (EM); however, few studies have examined these effects - and none used high-resolution displays. We examined the effects of font width on EMs by utilizing four fonts, from the Univers family, which varied in letter-width magnitude. Participants' (n = 25) reading speed, saccade velocity, and the duration/number of fixations and saccades were recorded. The Ultra Condensed font significantly influenced readability and yielded fewer fixations and saccades; longer fixation durations than the Roman and Extended fonts; and shorter saccade durations, relative to the other fonts. Readers efficiently adjusted their EMs such that no reading-speed differences were observed. The eye-tracking metrics revealed two trade-off effects (1) fewer and shorter EMs and (2) more and longer EMs, which were revealed by the font-width manipulation.

Oral cancer includes a variety of diagnoses of malignancies that manifest in the oral tissues. Prognosis and treatment depend on the site of involvement, the time of diagnosis, and the stage of the tumor. Early diagnosis of oral mucosal lesions facilitates the early detection of cancer, which is a key step for treatment. The purpose of this study was to investigate the relationship between delayed referral of patients with oral cancer and disease progression at the time of diagnosis.

In this cross-sectional study, data were collected from 108 patients with a definitive diagnosis of oral cancer by a standardized questionnaire. Data were analyzed by descriptive statistics, including mean, standard deviation, frequency, frequency percentage, and inferential statistics, including logistic regression analysis. P<0.05 was considered to be statistically significant.

The mean time of referral to a therapist was 17.73±22.80 weeks, with 53 (49.1%) patients having a delay of more than 10 weeks. Age, education level, smoking, disease stage, N class, M class, and type of cancer were not significantly associated with the incidence of delay (P>0.05). Patients whose first signs were significant bleeding and/or unrecovered ulceration showed a significant reduction in the delay time (OR=0.024 and P=0.038).

There was no significant relationship between the disease progression in oral cancer and the time elapsed from the onset of symptoms to diagnosis and treatment. Hence, it seems necessary to take appropriate measures to enhance public awareness of oral cancer and its symptoms.

There was no significant relationship between the disease progression in oral cancer and the time elapsed from the onset of symptoms to diagnosis and treatment. Hence, it seems necessary to take appropriate measures to enhance public awareness of oral cancer and its symptoms.This systematic review provides a high-quality synthesis of the empirical evidence regarding chemotherapy-induced peripheral neuropathy (CIPN) characteristics and patterns described in studies of children who received neurotoxic chemotherapy to treat cancer. PubMed, CINAHL, PsycINFO, and Embase were searched for articles published 2009 - 2019, yielding 861. Forty-two papers met the eligibility criteria, including 31 that described characteristics and patterns of vincristine-induced CIPN. Fifty-seven percent of articles were of low to moderate quality; measurement flaws were the most common limitations. The reported CIPN incidence varies widely (2.8%-100%) depending on risk factors (e.g., race) and the measurement approach. Incidence rates of sensory, motor, autonomic CIPN, and pain were 12-28%, 50-72%, 0.8-83% and 5.7-44%, respectively. The evidence suggests that sensory and motor neuropathy, pain, and functional deficits are common and can persist into adulthood. Caucasian race is a risk factor and, contrary to prior thinking, cumulative chemotherapy dosage alone does not predict CIPN severity. The influence of other risk factors is less clear, and studies to date have not explored potential interactions among race, genetics, age, sex, drug metabolism, and nutritional status, among other factors.

The association of triglyceride-rich lipoprotein-cholesterol (TRL-C) with recurrent cardiovascular events (RCVEs) has not been studied. Moreover, whether inflammation can affect TRL-C-associated cardiovascular risk is unknown. This study sought to examine the association between TRL-C and RCVEs, and whether this relationship is modulated by systemic inflammation in statin-treated patients with coronary artery disease (CAD) and nearly normal triglyceride.

In this study, 6723 CAD patients were consecutively enrolled, following a first CVE with triglyceride <2.3mmol/L. Baseline lipid profile and high-sensitivity C-reactive protein (hsCRP) levels were determined. All patients were searched for RCVEs. The risk of RCVEs was assessed across quartiles (Q) of baseline TRL-C and further stratified by the median of hsCRP.

Over a mean follow-up of 58.91±17.79 months, 538 RCVEs were recorded. After adjustment for potential confounders, Q4 of TRL-C was significantly associated with the risk of RCVEs, which remained unchanged after hsCRP stratification. When subjects were grouped according to both TRL-C and hsCRP levels, patients with Q4 of TRL-C and hsCRP had the highest increase of the risk of RCVEs compared with the reference group (TRL-C Q1-3 and hsCRP Q1-3; HR, 1.90; 95%CI 1.27-2.87). Furthermore, adding TRL-C to the original predicting model led to a slight but significant improvement.

The present analysis firstly showed that elevated TRL-C was associated with an increased RCVEs risk in statin-treated patients with CAD independent of systemic inflammation, suggesting that it might be a useful marker for risk stratification and a treatment target in this patient population.

The present analysis firstly showed that elevated TRL-C was associated with an increased RCVEs risk in statin-treated patients with CAD independent of systemic inflammation, suggesting that it might be a useful marker for risk stratification and a treatment target in this patient population.

Estimated cardiorespiratory fitness (eCRF) derived from algorithm correlates well with exercise testing-measured CRF, yet its clinical use for mortality risk stratification has not been systematically evaluated. This meta-analysis with dose-response analysis was conducted to quantify its association with risk of cardiovascular and all-cause mortality.

Electronic databases were searched for prospective cohort studies that investigated the association of eCRF with risk of cardiovascular and all-cause mortality. Study-specific multivariate-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per 1-metabolic equivalent (MET) higher of eCRF were pooled using a random-effects model.

Twenty-five datasets from 8 cohort studies that enrolled more than 170,000 participants were included. The summary HR per 1-MET higher of eCRF was 0.83 (95% CI 0.80 to 0.86) for cardiovascular mortality (11 datasets) and 0.83 (95% CI 0.78 to 0.88) for all-cause mortality (14 datasets) in the general population. These associations showed no sex-difference and were all linearly shaped (all p

≥0.27). The performance of eCRF (assessed by the area under the curve) in discriminating future risk of cardiovascular and all-cause mortality was higher than all its components (such as physical activity, resting heart rate, and body mass index, all p<0.05), but slightly lower than exercise testing-measured CRF.

Higher eCRF was independently associated with lower risk of cardiovascular and all-cause mortality in the general population, indicating that eCRF might hold the potential as an effective and practical risk prediction tool in epidemiological or population research.

Higher eCRF was independently associated with lower risk of cardiovascular and all-cause mortality in the general population, indicating that eCRF might hold the potential as an effective and practical risk prediction tool in epidemiological or population research.

This study aimed to investigate the extent to which hospitals and managers take the hospital-based health technology assessment (HB-HTA) approach into account in their decision-making processes regarding medical device/equipment acquisition.

The questionnaire was developed as a data collection tool and administered to a total of 186 administrators from 33 hospitals in Ankara.

All domains of HB-HTA are taken into consideration in both private and public hospitals but more in private hospitals than public hospitals (P<.001). The importance given to the domains of HB-HTA approach varies according to the characteristics of the hospitals and managers. In addition, it was seen that training hospitals were more likely to consider clinical effectiveness, and safety in specialty hospitals was more important. In addition, medical managers focus more on the clinical effectiveness, whereas administrative and financial managers are more concerned with cost/economic effectiveness. Moreover, the organizational aspects dimension of the HB-HTA was taken into account as the working duration of the managers in the health sector increased.

Hospitals and managers with different characteristics benefit from the domains of the approach at different levels. PCB chemical To contribute to the use of HB-HTA approach in hospitals and to increase awareness, regional initiatives can be undertaken by encouraging hospitals.

Hospitals and managers with different characteristics benefit from the domains of the approach at different levels. To contribute to the use of HB-HTA approach in hospitals and to increase awareness, regional initiatives can be undertaken by encouraging hospitals.Biphenotypic acute leukemias (BAL) are known as a type of leukemia involving cells with myeloid and along with lymphoid origin, in which genomic changes are detected. It has been stated that the most common genomic changes in BAL are t(9;22) and the translocations of the 11q23 region, these anomalies cause poor prognostic effects. We detected trisomy 5 (+5) in addition to the double Ph chromosome in a case where we investigated the genomic changes using molecular and conventional cytogenetic methods. Bone marrow transplantation was planned due to the poor response to prednisone. According to the information we have obtained, our report will be the first article to discuss the aberrations found in addition to the Ph chromosome in BAL and the effect of these aberrations on prognosis. However, the double observation of the Ph chromosome, which has a poor prognostic effect, is expected to affect the prognosis more negatively, this case will contribute to the literature in terms of trisomy 5. We think that more case reports are needed to reveal the anomalies and their prognostic significance in BAL.

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