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The enhanced workflow in endoscopy was carried out in 106 customers with required endoscopy through the division of Gastroenterology, Third Xiangya Hospital, Central Southern University between January 24, 2020 and February 26, 2020, and no instance of cross-infection had been presented among the list of hsp90 inhibitors health staffs, clients and members of the family. The medical information of inpatients when you look at the Department of Kidney Transplantation from January 24, 2020 to February 29, 2020 were retrospectively examined. Since the outbreak of COVID-19, we carried out phone, Wechat follow-up, and online training for kidney transplant recipients and patients on waiting-list for kidney transplantation 1 by 1. We also purely screened for COVID-19 in outpatients. To make sure the protection of medical staff and recipients and also to lower the transmission danger of COVID-19, we now have made detailed methods to prevent COVID-19, which primarily included 6 components of preventive approaches, such as for example kidney transplant center, renal transplant ward, patients on waiting-list for kidney transplantation, renal transplant procedure, medical staff self-protection, and postoperative followup of kidney transplant recipients. There have been entirely 47 inpatients including 20 recipients that has only obtained kidney transplantation in the meantime, 2 577 kidney transplant recipients, 1 689 patients on waiting-list for renal transplantation, and 794 outpatients in our hospital. No situation of COVID-19 took place this era. Through strictly implementing proactive and preventive methods, we steer clear of the event of COVID-19 in carrying out kidney transplantation into the epidemic period.Through purely implementing proactive and preventive approaches, we prevent the event of COVID-19 in carrying out kidney transplantation when you look at the epidemic period.To suggest the architectural design for the big basic medical center in the face of public wellness emergencies, we examined the problems, techniques, dilemmas and countermeasures for the reconstruction associated with isolation ward from the existing medical building design of an over-all hospital. The affected areas found the requirements of separation ward within the repair, and understood the corresponding partition and split of individuals. However the cost of occupying the health room must certanly be concerned. General medical center ought to be notified to prospective risks of public wellness problems. The attributes of different construction kinds, defects, therefore the purpose of a medical facility should be thought about in the construction, rebuilding, and development for the medical center, which shouldnot only meet up with the needs of this development of the hospital daily usage but additionally give consideration to dealing with emergent public wellness activities. We could follow the reasonable design, including setting up a firewall-like product between your channel plus the flooring, a regular ward at ordinary times, and an unbiased area for emergency by pulling down the gate. This tactic can not only prevent the problem of reasonable utilization rate regarding the area occupied by the matching area into the ward for diseases spread by atmosphere and droplets, maximizing the efficiency of this medical website, but in addition steer clear of the dilemma of emergency response to the temporary reconstruction.Based on archival products, the Xiangya's anti-epidemic history in a century from its institution to 2020 is divided into 4 phases. The very first phase (1906-1926), Edward Hicks Hume and YAN Fuqing, the creators of Xiangya, prevented and controlled smallpox and plague. The 2nd stage (1929-1953), during the resumption of Xiangya, pupils prevented and controlled cholera, plague, dysentery, typhus, and other infectious conditions. When you look at the third phase (1953-1999), in a peacetime, Xiangya actively fought against schistosomiasis, hydatidosis, malaria, leprosy, tuberculosis and other epidemics. The fourth phase (2000-2020), the era of Central South University. Medical staff in Xiangya fight SARS, influenza A (H1N1) flu, Ebola hemorrhagic fever, coronavirus disease 2019, etc. Within the last hundred years, Xiangya individuals joined together to distribute benevolence and love, apply medical knowledge and skills, combat the epidemic and rescue men and women in troubles, which made a great share to the motherland and the individuals.Chronic myeloid leukemia (CML) is among the common hematological malignancies and described as the forming of Philadelphia (Ph) chromosome. Recently, tyrosine kinase inhibitors (TKI) treatment greatly improved the prognosis of CML. But, the options could be limited when an individual develops old-fashioned TKI opposition or gene mutation. Herein, we reported a case. A 38-year-old male CML patient created a BCR-ABL1 gene mutation of T315I after 2.5 many years of TKI treatment, including imatinib and dasatinib. We modified the therapy with the combined application of dasatinib and axitinib. BCR-ABL1 gene copies dropped down and reached an early on molecular response at 2 months later on. Consequently, he obtained hematopoietic stem cell transplantation. Axitinib and dasatinib were sent applications for another half year after the allogeneic hematopoietic stem cellular transplantation (allo-HSCT). Two years after the allo-HSCT, the BCR-ABL1 gene had been however undetectable.