Dalsgaardmitchell0450
To investigate the effect of programmed nursing combined with cognitive behavioral intervention on clinical efficacy and neurological function of patients with intracerebral hemorrhage (ICH).
In this retrospective study, 96 patients with ICH admitted to our hospital were enrolled and divided into a programmed group and a joint group, with 48 cases in each group. Patients in the programmed group were treated with programmed nursing while those in the joint group were given cognitive behavior intervention based on programmed nursing, for 28 days. The Fugl-Meyer (FM) Assessment Scale was used to evaluate the motor function of patients, the Barthel index to analyze the activities of daily living (ADL), and the National Institutes of Health Stroke Scale (NIHSS) and Glasgow Outcome Scale (GOS) to assess the neurological function. The quality of life of patients was evaluated by the World Health Organization quality of life Brief Version (WHOQOL-BREF), and the nursing satisfaction of patients or their families ween the two groups (t=0.049, P=0.960) before nursing; after nursing, the score increased significantly in both groups, with a significant difference between the two groups (t=15.970, P<0.001). The satisfaction was 95.83% in the joint group, which was higher than that of 83.33% in the programmed group (χ
=3.913, P=0.048). The joint group also had fewer adverse reactions than the programmed group (χ
=7.401, P=0.007).
Programmed nursing combined with cognitive behavioral intervention can improve the clinical efficacy of patients with ICH, improve limb motor ability, and reduce neurological deficits, with high safety.
Programmed nursing combined with cognitive behavioral intervention can improve the clinical efficacy of patients with ICH, improve limb motor ability, and reduce neurological deficits, with high safety.
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Genetic factors are reported to play an essential role in IgAN progression. This study was designed to investigate the association between
and
and IgAN risk among the Chinese Han population.
Six SNPs were genotyped. A logistic regression model was used to calculate the effects of the candidate SNPs on IgAN. The SNP-SNP interaction was analyzed using multifactor dimensionality reduction.
We observed that only
had a relationship with IgAN. The results indicated an association between the genotype "CC" and a decreased IgAN risk (OR=0.44,
=0.014). The stratification analysis of the patients over 35 years old showed that rs3931698 contributes to IgAN susceptibility in the "GT" genotype (OR=1.78,
=0.038), while rs8044565 showed a significantly decreased risk-effect with IgAN ("T", OR=0.59,
=0.006; "CC", OR=0.15,
=0.015; "CC-CT", OR=0.59,
=0.023; Log-additive, OR=0.56,
=0.005). rs8044565 was correlated with a decreased susceptibility of IgAN in males ("CC", OR=0.27,
=0.006) and in patients with a Lee's grade ≥III ("CC", OR=0.46,
=0.046). We found rs8044565 is related to systolic blood pressure and urinary casts and rs3852740 has a relationship with the serum C3 and hemoglobin levels (
<0.05).
The present study demonstrated that the SNPs in long non-coding RNAs might be related to IgAN.
The present study demonstrated that the SNPs in long non-coding RNAs might be related to IgAN.
To innvestigate the rehabilitation effects of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training on cognitive impairment in patients with traumatic brain injury (TBI) by using multimodal magnetic resonance imaging.
Clinical data of 166 patients with cognitive impairment after TBI were retrospectively analyzed. The patients were assigned into an observation group and a control group according to different treatment methods, with 83 cases in each group. The observation group was given rTMS + cognitive training, and the control group was given cognitive training only. The changes in GCS score, the Cho/Cr, Cho/NAA and NAA/Cr ratios examined by MRSI, the score of cognitive impairment, the grading of cognitive impairment, and the changes in modified Barthel index were observed and compared between the two groups.
The GCS score, and the ratios of Cho/Cr, Cho/NAA and NAA/Cr after treatment were better than those before treatment in both groups and were lower in the observation group compared with the control group (all P<0.05). The score and grading of cognitive impairment as well as modified Barthel index after treatment were all significantly better in the observation group than in the control group (all P<0.05).
rTMS can improve the rehabilitation effect on cognitive impairment in patients after TBI and is recommended for clinical use.
rTMS can improve the rehabilitation effect on cognitive impairment in patients after TBI and is recommended for clinical use.
To investigate the correlation of the salivary expression levels of developmental endothelial locus-1 (Del-1) and interleukin 17 (IL-17) with the severity of periodontal disease in patients with type 2 diabetes mellitus (T2DM).
Fifty-seven patients with T2DM and fifty-seven patients with T2DM complicated with chronic periodontitis (CP) admitted to our hospital from March 2020 to March 2021 were enrolled as the research objects and assigned to the T2DM group and T2DM+CP group respectively. Additionally, 57 healthy controls from the hospital physical examination center during the same period were included as the healthy controls. General information of all the enrolled participants was collected to measure the levels of glycated hemoglobin (HbA1c), salivary inflammatory factors, and salivary Del-1 and IL-17, as well as homeostasis model assessment of insulin resistance (HOMA-IR).
HbA1c in the T2DM group and T2DM+CP group was significantly higher than that in the healthy control group. Gingival index (GI),ted with CP, indicating their correlation with the occurrence of CP in T2DM patients.
To evaluate the effect of emergency care on the mental health and recovery of limb function in myocardial infarction (MI) patients.
We recruited 106 MI patients consecutively admitted to the emergency center of our hospital from June, 2016 to January, 2019. Among them, 51 underwent routine care (the control group) and 55 underwent emergency care (the observation group). The rescue success rates, the pre-hospital times, the emergency rescue times, and the door-to-balloon times were recorded and compared. The patients' heart rates, respiratory frequencies, and blood pressure levels were monitored after the care. The self-rating anxiety scale (SAS) and the self-rating depression scale (SDS) were used to evaluate the patients' psychological states. The patients' limb function and activities of daily living (ADL) were evaluated using the Fugl-Meyer assessment (FMA) and the modified Barthel index (MBI), respectively. The incidences of complications were compared between the two groups. The Short-Form 36 Item Hehy of promoting.
Emergency care contributes to the improvement of mental health and limb function, as well as MI patient prognosis, so it is well worthy of promoting.
The role of surgery type in the prognosis of triple-negative metaplastic breast cancer (TN-MBC) patients remains controversial. Our study was designed to assess the role of surgery type in patient outcomes.
Data from the Surveillance, Epidemiology, and End Results database were extracted to analyze patients with TN-MBC between 2010 and 2016. Kaplan-Meier analyses and multivariate Cox proportional models were used to estimate the prognoses.
We included 1,146 patients with a median follow-up time of 26 months (range 1-83 months). 470 (41.0%), 369 (32.2%), 244 (21.3%), and 63 (5.5%) patients underwent breast-conserving surgery (BCS), total mastectomy (TM), radical mastectomy, or no surgery. With the multivariate Cox analysis, the prognosis was related to age, TNM stage, and surgery type. With the Kaplan-Meier analysis, the more radical the operation, the worse the prognosis for the patients in the entire cohort. Within stage I-III disease, the best prognoses were observed in the patients undergoing BCS, followed by TM and radical mastectomy. The adjusted survival analysis showed that the prognoses of the patients undergoing BCS were better than the prognoses of the patients undergoing TM. Within stage IV disease, the patients who underwent an operation had a better prognosis regardless of the mode.
Patients undergoing BCS had the best prognoses among the patients with early and locally advanced TN-MBC. This improves our understanding of the clinicopathological and prognostic features of this rare entity but also provides more convincing therapeutic guidelines for TN-MBC.
Patients undergoing BCS had the best prognoses among the patients with early and locally advanced TN-MBC. This improves our understanding of the clinicopathological and prognostic features of this rare entity but also provides more convincing therapeutic guidelines for TN-MBC.
Orthodontics, as a common way of orthodontic treatment, is usually to maintain oral health and protect periodontal tissue. The self-ligating appliance technique, since its advent in the 1930s, have been rather popular ammong the majority of orthodontists. This study was to determine that self-ligating appliance can reduce inflammation in gingival crevicular fluid (GCF) of patients receiving orthodontic treatment and keep periodontal health.
The clinical data of 97 orthodontic patients admitted to the Department of Stomatology of Fujian Provincial Hospital, Fujian Provincial Clinical College of Fujian Medical University from March 2019 to March 2020 were analyzed retrospectively. read more Among them, 42 patients receiving orthodontic treatment with traditional MBT straight-wire appliance (SWA) were included in the control group (CG) and 55 patients treated with self-ligating appliance were collected as the observation group (OG). The two cohorts were compared with respect to the following aspects curative effect, p;0.05). Oral related QoL and orthodontic satisfaction were higher in OG, and the differences were statistically significant (P<0.05).
Compared with traditional SWA, the self-ligating appliance in orthodontic treatment contributes to higher efficacy and satisfaction, less local inflammatory reaction, and significantly improved periodontal condition and oral health of patients.
Compared with traditional SWA, the self-ligating appliance in orthodontic treatment contributes to higher efficacy and satisfaction, less local inflammatory reaction, and significantly improved periodontal condition and oral health of patients.
The purpose of this study is to explore the effect of fine nursing interventions on the clinical efficacy of acute alcoholism patients (AA).
A total of 100 patients with AA were included in the study. Among them, 51 patients who underwent fine nursing intervention were assigned to the research group (RG), and the remaining 49 patients were treated with routine nursing intervention and were assigned to the control group (CG). The nursing efficacy, the recovery times (consciousness and limb movement), the incidences of adverse events, the nursing compliance, the psychological states (the Symptom Checklist 90 and SCL-90 scores), and the nursing satisfaction levels were observed and compared between the two groups.
Compared with the CG, the nursing efficacy, the compliance, and the nursing satisfaction levels in the RG were markedly higher, while the consciousness and limb movement recovery times were significantly shorter; moreover, the RG presented a significantly lower incidence of adverse events and SCL-90 scores than the CG.
