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To demonstrate possible complications of a new IOL (intraocular lens) for sutureless secondary scleral implantation and modifications of the surgical technique to optimise outcomes.

Retrospective study of 16 eyes (16 patients) who underwent a secondary IOL implantation using the Carlevale IOL (Soleko, Italy) with two anchor haptics for intrascleral implantation (mean follow-up 2.2 months).

Visual acuity did not improve statistically significantly postoperatively (p = 0.601). Seven (44 %) patients suffered from postoperative hypotonia (intraocular pressure < 5 mmHg) during the first three postoperative days.

Due to the early postoperative hypotony, we decided to modify the surgical technique. We present several suggestions to optimize the technique and outcome like positioning the sclerotomies at the 2 and 8 o'clock positions, using 27 G trocars only and suturing the frown incisions using self-resorbing sutures.

Due to the early postoperative hypotony, we decided to modify the surgical technique. We present several suggestions to optimize the technique and outcome like positioning the sclerotomies at the 2 and 8 o'clock positions, using 27 G trocars only and suturing the frown incisions using self-resorbing sutures.

Pre-exposure prophylaxis (PrEP) is a pillar of our national strategy to end the HIV epidemic. However, one of the largest obstacles to realizing the effectiveness of PrEP is expansion of prescription to all patients at risk for HIV. In this vignette-based study, we sought to investigate medical students' decision-making regarding PrEP by presenting fictional patients, all of whom had HIV risk-factors based on sexual behavior.

We systematically varied patients' sexual orientation or gender identity (heterosexual female, gay male, bisexual male, transgender male, transgender female, gender nonbinary person). We assessed the medical students' willingness to prescribe PrEP to the patients as well as their perceptions of the patients' HIV-risk and behavior.

A total of 670 U.S. medical students completed the study. The heterosexual female patient was least frequently identified as a PrEP candidate, was viewed as least likely to adhere to PrEP, and the most likely to engage in condomless sex if prescribed PrEP; however, was considered at lower overall HIV-risk. ALK signaling pathway Lower perceived HIV-risk and anticipated PrEP adherence were both associated with lower willingness to prescribe PrEP. Willingness to prescribe PrEP was highest for the gay male patient and lowest for the heterosexual female.

These analyses suggest that assumptions about epidemiological risk based on patients' gender identity or sexual orientation may reduce willingness to prescribe PrEP to heterosexual women, ultimately hindering uptake in this critical population.

These analyses suggest that assumptions about epidemiological risk based on patients' gender identity or sexual orientation may reduce willingness to prescribe PrEP to heterosexual women, ultimately hindering uptake in this critical population.Nurse educators still struggle with teaching and assessing end-of-life communication skills. Many resources are available to assist in teaching end-of-life communication, but few tools exist to assess performance learning outcomes. Behavior evaluation tools must be user-friendly and provide beneficial student feedback. Quality end-of-life patient care and nursing job satisfaction depend on skillful communication. The purpose of this study was to evaluate the reliability of an end-of-life communication clinical simulation evaluation performance rubric. Moderate interrater consistency and agreement were found between 3 evaluators when assessing the same students. All simulation evaluators agreed that the performance rubric was user-friendly and provided rich feedback for students during simulation debriefing. The performance evaluation tool was moderately effective when evaluating end-of-life communication performance and appears as a worthy framework for other behavior evaluations.

This study aimed to investigate the mediating effects of eudemonic well-being (EWB) at work for the associations between psychosocial work environment (PWE) and overall EWB among Japanese workers.

We conducted a cross-sectional study using data from a 2018 survey. PWE measures included job demands, job control, and supervisor and coworker support. Path analysis using structural equation modeling (SEM) and mediation analysis were applied to examine the mediating effects of work EWB.

A total of 834 workers were analyzed. Work EWB completely mediated the associations of job control (β = 0.288, p < 0.001) and coworker support with overall EWB (β = 0.178, p < 0.001).

The effects of job control and coworker support associated with overall EWB were fully mediated by work EWB.

The effects of job control and coworker support associated with overall EWB were fully mediated by work EWB.

To justify the capital investment, employers require proof of benefit of digital mHealth beyond symptomatic improvement.

A systematic review and meta-analysis were conducted to identify studies investigating digital mHealth interventions for employees and their effects on workplace outcomes.

We identified 28 eligible studies, (8023 employees) comparing digital mHealth interventions to controls. Small significant effects at post-intervention in engagement (g = 0.19), and productivity (g = 0.16) were found. Sustained effects were observed, engagement (g = 0.24) and productivity (g = 0.20). There was a wide range of study heterogeneity (I2 = 16% to 94%).

In RCTs digital mHealth interventions demonstrate small, potentially sustained efficacy on employee's engagement and productivity. Similar small yet non-significant effect sizes were seen for absenteeism and presenteeism. This supports the need to find ways of enabling employers to deliver these low-cost digital mHealth interventions that can help improve employee's mental health.

In RCTs digital mHealth interventions demonstrate small, potentially sustained efficacy on employee's engagement and productivity. Similar small yet non-significant effect sizes were seen for absenteeism and presenteeism. This supports the need to find ways of enabling employers to deliver these low-cost digital mHealth interventions that can help improve employee's mental health.

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