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teins to 79.6%. The effect of L. barbarum berries, characterized by an increase in high density lipoproteins in rat blood (by 62.3%), may be due to a higher content of vitamins C, E and selenium (35, 11 and 22% more than in L. chinense), the presence of phytosterols and phytostanols, in particular dodecanoic acid. CONCLUSION The data obtained indicate a pronounced antioxidant effect of L. barbarum and L. chinense berries and the possibility of their use in the diet to correct lipid metabolism disorders. Copyright© GEOTAR-Media Publishing Group.The high incidence of nutritional deficiency in cystic fibrosis continues to be an urgent problem in pediatrics. This is due to the multifactorial nature of these violations, one of which is the lack of effectiveness of nutritional correction. The aim of the research was to assess the actual diet of children and adolescents suffering from cystic fibrosis in order to develop an algorithm for individual approaches to correcting nutritional status. MATERIAL AND METHODS 150 children (boys - 85, girls - 65) aged 1 year to 18 years (average age 6.4±5.2 years) with a confirmed diagnosis of cystic fibrosis have been examined. Depending on age, the children were divided into groups the 1st group consisted of 40 children from 1 year to 2 years (average age 1.9±0.7 years); 2nd group - from 3 to 5 years (n=41, 4.4±1.0 years); 3rd group - from 6 to 9 years (n=43, 7.7±1.1 years); 4th group - from 10 to 18 years old (n=26, 13.1±2.5). The actual nutrition was evaluated by questionnaire for 3 days, including one day off. Body mass, height have been measured, and body mass index (BMI) have been calculated. RESULTS AND DISCUSSION Only children of the first three years of life had an optimal diet for this disease in terms of energy value. At the age of 3 years and older, the deficit of energy intake increased, reaching 32% of the individual requirement in adolescence (10-18 years). The structure of nutrition revealed an imbalance of the main nutrients in the direction of the predominance of the lipid component (more than 40% of the energy value) and increased intake of saturated fatty acids, with a reduced proportion of protein and carbohydrates. There was a lack of dietary intake of a number of vitamins (C, B1, B2, A, E, D) and mineral substances (iron, potassium). CONCLUSION The study showed the need for an individual approach to the correction of diet energy value and macronutrient intake in children with cystic fibrosis. Copyright© GEOTAR-Media Publishing Group.Psoriasis is a chronic relapsing disease that affects about 2% of the world's population and leads to medical and social losses. There is evidence of the effect of nutritional factors on the course of psoriasis in modern literature. The aim of the research was to analyze modern domestic and foreign literature on the role of nutritional factors, food allergies and the state of the gastrointestinal tract in the etiopathogenesis of psoriasis Material and methods. The electronic resources were used in preparing the article the PubMed/MEDLINE portal, "Scientific Electronic Library eLIBRARY.RU". The following filters and keywords were requested psoriasis and nutrition, food allergies and psoriasis, gastrointestinal manifestations and psoriasis, diet and psoriasis, obesity and psoriasis. Results and discussion. The role of nutrition as a predictor of the development of psoriatic skin rashes and exacerbation of the disease has been discussed. The mechanisms of the positive influence of the correction of metabolic disn with standard systemic therapy. βSitosterol Copyright© GEOTAR-Media Publishing Group.The last two or three decades in the epidemiology of nutrition empirical approaches to assessing the diet of the population are increasingly being used. However, in Russian studies, these approaches are used extremely rarely, which may be due to insufficient knowledge of the essence, methodological aspects and the field of application of posterior dietary patterns. In this regard, the aim of this review was to highlight the essence, methods and main results of using empirical approaches to assessing the diet of the population. Results. This review discusses the main methodological features of multivariate analysis methods - factor analysis (principal component analysis) and cluster analysis. The main trends of dietary patterns characteristic of the epidemiology of nutrition, and various in different countries and regions are shown. The results of studies of the impact of dietary patterns on some indicators of health status (cardiovascular and oncological diseases, diseases of the musculoskeletal system, diabe their testing in Russian conditions, which, perhaps, will give new knowledge about the dietary patterns formation and its impact on the health status of Russians. Copyright© GEOTAR-Media Publishing Group.Objective To determine the prevalence of excessive daytime sleepiness among medical students and establish a relationship between self-perceived sleepiness and psychological distress. Methods In a cross-sectional study, 441 medical students from a public-sector university in Pakistan completed a questionnaire from August to December 2018. The questionnaire included the Epworth Sleepiness Scale (ESS), which measured daytime sleepiness, and the 12-item General Health Questionnaire (GHQ-12), which measured mental health. Pearson correlations and student t tests were used for comparisons with a significance level of P less then .05. Results Many of the students (44.9%) obtained a high score (≥ 10) on the ESS (ie, experience excessive daytime sleepiness). On average, higher scores on the ESS correlated with higher scores on the GHQ-12. A statistically significant correlation (P less then .05) between ESS scores and GHQ-12 scores was obtained when the students with higher (≥ 10) ESS scores were compared with students with lower ( less then 10) ESS scores. Conclusions Excessive daytime sleepiness is frequent among medical students and significantly associated with psychological distress. Thus, careful investment in planning appropriate university policies and class schedules is required to encourage healthy and adequate sleep among students, which could have a significant impact on learning, academic performance, and health of medical students. © Copyright 2020 Physicians Postgraduate Press, Inc.