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In conclusion, physiological concentrations of androgens have very strong genotoxicity, most likely by generating stalled TOP2ccs. This article is protected by copyright. All rights reserved.The crocodilian naris is regulated by smooth muscle. The morphology of this system was investigated using a combination of gross, light microscopic, and micro-CT analyses, while the mechanics of narial regulation were examined using a combination of Hall Effect sensors, narial manometry, and electromyography. Alligator mississippiensis, like other crocodilians, routinely switches among multiple ventilatory mechanics and does not occlude the nares during any portion of the ventilatory cycle. In a complex that is unique among vertebrates, a single block of smooth muscle functions in dilation when active, and in constriction when passive. read more The alligator nares may include one of the best examples of a muscle that functions in "pushing" as well as "pulling." The central muscle for narial regulation, the dilator naris, can legitimately be viewed as its own antagonist. © 2020 Wiley Periodicals, Inc.There is mounting evidence that telemental health is an effective delivery method for treating a variety of mental, emotional, behavioral, and relational health problems. While many of the therapeutic skills leading to the effectiveness of face-to-face treatments are transferable, the effectiveness of telemental health requires unique skills. The purpose of this phenomenological study was to determine the experience of learning how to use videoconferencing to deliver relationally focused mental health care. Participants included 10 graduates of a COAMFTE-accredited master's degree program emphasizing training in telemental health. Each student had practicum placements that required videoconferencing to deliver relationally based psychotherapy. Analysis of interview data revealed (a) personal reservations about distance delivery; (b) the importance of scaffolding student learning through curriculum, supervision, and mental health-care delivery protocols; (c) the technological barriers associated with this delivery method; and (d) overcoming technological barriers through intentionality. © 2020 American Association for Marriage and Family Therapy.Animal acoustic communication often takes the form of complex sequences, composed of multiple distinct acoustic units, which can vary in their degree of stereotypy. Studies of sequence variation may contribute to our understanding of the structural flexibility of primates' songs, which can provide essential ecological and behavioral information about variability at the individual, population, and specific level and provide insights into the mechanisms and drivers responsible for the evolutionary change of communicative traits. Several methods have been used for investigating different levels of structural information and sequence similarity in acoustic displays. We studied intra and interindividual variation in the song structuring of a singing primate, the indri (Indri indri), which inhabits the montane rain forests of Madagascar. Indri groups emit duets and choruses in which they combine long notes, short single units, and phrases consisting of a variable number of units (from two to six) with slightly descfindings of rhythmic features and song repertoire size of the indris, which also suggested that female songs are potentially less stereotyped than those of males. © 2020 Wiley Periodicals, Inc.AIM The aim of this study was to investigate language ability in internationally adopted children aged 7-8 years with and without a unilateral cleft lip and palate. METHODS We compared 27 internationally adopted children with a unilateral cleft lip and palate, adopted from China, with a group of 29 children without a cleft lip and palate, adopted from different countries. Participants were recruited from two cleft lip and palate teams In Sweden and through adoption organisations. Assessments were performed using standardised tests of speech and of receptive and expressive language ability. In addition, a parental questionnaire in which speech, language and communication aspects were rated was used. RESULTS There were no significant differences in language ability between the groups. The only difference was related to speech ability, where the internationally adopted children with unilateral cleft lip and palate scored significantly lower. However, a high proportion of children in both groups scored low on measures of expressive language compared with test norms. CONCLUSION The results suggested that having a cleft lip and palate did not increase the risk of language difficulties. Instead, being internationally adopted may be associated with a risk of delayed language development lasting for several years post-adoption. This article is protected by copyright. All rights reserved.OBJECTIVES (1) To determine the false positive rate among newborns with prenatally suspected CoA within the UCLA Health system, (2) to compare patient and maternal interventions and outcomes between false positive cases and normal controls, and (3) to determine the timing of clinical presentation of CoA. METHODS We performed a single-center, retrospective case control study of all fetuses with suspected isolated CoA who underwent both fetal echocardiographic evaluation and subsequent delivery at UCLA between January 1, 2011 and December 31, 2018. Maternal and neonatal medical records were reviewed for demographic and clinical data, for cases of suspected CoA and for controls. A separate review of our institution's surgical database was performed to identify characteristics of all patients (neonatal and pediatric) with isolated CoA who underwent surgical repair during the same time period. RESULTS Among the 50 fetal cases of isolated suspected CoA who delivered at our institution, 47 patients (94%) were found to be normal (false positives). Compared with normal controls, patients with suspected CoA were more likely to have delayed maternal bonding, delayed feeding, admission to the intensive care unit, performance of neonatal echocardiograms, initiation of IVF and initiation of PGE1, and a longer length of hospital stay. Among the 38 patients undergoing CoA repair at our institution during the study period, 4 patients were prenatally diagnosed and no patient presented clinically with symptoms before 48 hours after delivery. CONCLUSION Compared with normal controls, patients with prenatally suspected coarctation are more likely to have delayed maternal bonding, delayed feeding, more frequent neonatal echocardiograms, and longer length of hospital stay. Further refinement of neonatal management may improve postnatal care. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

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