Cruzmann4497

OBJECTIVE To verify the Traditional Chinese Medicine (TCM) theory that kidney-Qi deficiency (KQD) is considered to be the main cause of aging using cross-sectional study. METHODS Demographic and lifestyle characteristics of 90 healthy participants were collected with a self-administered questionnaire. KQD syndrome was diagnosed according to Deng's diagnosis standard. Creatinine-adjusted urinary 8-hydroxy-2'-deoxyguanosine (8-OH-dG) and 8-isomeric-prostaglandin2α (8-iso-PGF2α), salivary advanced oxidation protein products (AOPPs), malondialdehyde (MDA) and dehydroepiandrosterone-sulfate (DHEA-S) were selected as aging markers and measured using enzyme-linked immunosorbent assay. RESULTS No significant differences were observed in participant characteristics between the KQD group and non-KQD (NKQD) group (P > 0.05). Levels of 8-OH-dG, 8-iso-PGF2α, AOPPs, and MDA increased with age, except for a slight decrease in 8-OH-dG in the older group. The increase in 8-iso-PGF2α was significant (P less then 0.05). DHEA-S significantly decreased with increasing age (P less then 0.01). 8-OH-dG levels were higher in the KQD group compared with the NKQD group. Levels of urinary 8-iso-PGF2α, salivary AOPPs, and MDA in the KQD group were lower than in the NKQD group. Salivary DHEA-S was higher in the KQD group compared with the NKQD group. However, differences between KQD group and NKQD group were not significant. CONCLUSION The current results suggested that KQD syndrome, as diagnosed by Deng's standard, does not underlie the aging phenotype.OBJECTIVE To investigate the influence of the quickness and duration of De Qi (or Qi arrival) on the analgesic effect of acupuncture in primary dysmenorrhea patients with a cold and dampness stagnation pattern. METHODS Sixty-eight patients were randomly assigned to the De Qi group (deep needling with thick needles and manipulation, n = 17) or the non-De Qi group (shallow needling with thin needles and no manipulation, n = 51). Both groups underwent needling at Sanyinjiao (SP 6) for 30 min. The visual analogue scale was used to measure the degree of menstrual pain, and the Acupuncture De Qi Clinical Assessment Scale was used to assess De Qi. Only data from patients who experienced actual De Qi were included in the analysis. RESULTS Thirty-nine patients experienced actual De Qi. Patients who experienced actual De Qi in the De Qi group (n = 14) felt De Qi more rapidly (P = 0.028) and for a longer duration (P = 0.04) than patients who experienced actual De Qi in the non-De Qi group (n = 25). Both groups showed a reduction in the visual analogue scale score for pain after treatment. The analgesic effect did not significantly differ between the two groups. The occurrence time of De Qi showed a significant negative correlation with pain reduction at 20 and 30 min after needle removal (P less then 0.05). There was no correlation between the duration of De Qi and the therapeutic effect. CONCLUSION In primary dysmenorrhea patients with a cold and dampness stagnation pattern, quicker onset of De Qi when needling Sanyinjiao (SP 6) achieves a better analgesic outcome. However, a longer duration of De Qi does not affect the degree of analgesia. Compared with minimal acupuncture, active acupuncture stimulation achieves a more rapid onset and longer duration of De Qi.OBJECTIVE To investigate the effect of a modified Banxia Xiexin decoction (MBXD) plus chemotherapy on postoperative adverse reaction in patients with stage Ⅲ colon cancer in patients whose symptoms were identified as cold-heat complicated pattern in terms of the theory of Traditional Chinese Medicine (TCM). METHODS A prospective non-randomized control study of patients with stage Ⅲ colon cancer in Beijing Shijitan Hospital and Guang'anmen Hospital between January 2012 and December 2013. A total of 80 patients were divided into experimental group (MBXD + chemotherapy) and control group (chemotherapy). The adverse reactions, life quality and disease-free survival (DFS) were compared between the two groups. RESULTS The cold-heat complex pattern was released in 94.3% of patients in experimental group whereas 62.2% in control group (P less then 0.05). Life quality was improved in 24 vs 14 cases, stabilized in 9 vs 14 cases whereas decreased in 2 vs 15 cases in experimental group and control group, respectively (P less then 0.05). The average DFS was 22.371 months in experimental group, while 13.932 months in control group (P less then 0.05). CONCLUSION MBXD combined with chemotherapy may significantly relieve clinical symptoms, reduce chemotherapy associated adverse effects, improve life quality, and prolong DFS of patients with stage Ⅲ colon cancer (cold-heat complicated pattern).OBJECTIVE To study the effect of acupuncture on blood pressure (BP) control in hypertensive patients. METHODS A total of 80 out-patients with primary hypertension at the family medicine unit and the social security unit were randomly and equally divided into an acupuncture plus medication group and a control group that received only medication. Patients of the acupuncture group were treated with acupuncture stimulation of Yinlinquan (SP 9), Zusanli (ST 36), Taichong (LR 3), Hegu (LI 4), Quchi (LI 11), Neiguan (PC 6) for 30 min, once per week, continuously for eight weeks. In addition, both groups received amlodipine (5 mg) once daily, continuously for eight weeks. Systolic BP (SBP), diastolic BP (DBP) and mean arterial BP (mABP) were recorded. selleck kinase inhibitor Data were analyzed by Mann-Whitney U test. RESULTS SBP of the 40 cases in the acupuncture group significantly improved compared to the medication only group [Z =－ 4.265, P (2-tailed) = 0.001] and DBP of acupuncture group was lower than that of the control group (Z =－ 2.813, P = 0.005). mABP of acupuncture group was the marked improvement in the reduction of blood pressure to that of medication group in controlling blood pressure. (Z = －2.416, P = 0.016). CONCLUSION These results indicate that the effectiveness of acupuncture with the acupuncture group is superior to the only medication group in the control of hypertension.OBJECTIVE To observe the effect of herb-partitioned moxibustion (HPM) for primary dysmenorrhea. METHODS Six hundred and forty patients were randomized assigned (1∶1) to HPM group and control group. Duration of treatment was 3 months with 3 month follow-up. The primary outcome was pain relief measured by visual analogue scale (VAS). The second outcomes were Cox Menstrual Symptom Scale (CMSS), menstrual pain duration and frequency of analgesics usage. The exploratory outcome included quality of life, RESULTS After the 3-month treatment and follow-ups, the pain intensity measured by VAS was significantly reduced in both groups compared with baseline (P less then 0.05), and it was significantly decreased in HPM group than that of control group (P less then 0.001). The higher proportion of participants in the HPM group had a decrease of at least 50% in VAS at the end of treatment, as compared with the control group (P less then 0.001). At the 3rd and 6th month, the menstrual pain duration, CMSS score and frequency of analgesics usage in HPM group were significantly lower than those of control group (P less then 0.