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OBJECTIVE The prevalence of obesity and severe obesity among adolescents has increased dramatically in developing countries. However, the distribution of cardiometabolic risk factors through the severity of obesity continuum is relatively unknown among youth. The aim of this study was to evaluate the association of weight categories with cardiometabolic risk factors among Brazilian adolescents. METHODS ERICA (The Study of Cardiovascular Risk in Adolescents) was a multicenter, school-based, cross-sectional study composed of Brazilian adolescents (12-17 y of age). Severity of obesity was classified according to the International Obesity Task Force reference values for body mass index (BMI) and several cardiometabolic risk factors were measured after clinical and biochemical exams and categorized using standard definitions of abnormal values. RESULTS Among the 37 892 adolescents enrolled, 8708 had excess weight, being classified with overweight (17.2%), obesity (5.6%), and severe obesity (1.3%). Increasing severity of obesity was associated with a worse cardiometabolic profile in the overall sample. Multivariable models that controlled for age, sex, skin color, socioeconomic status, physical activity, and total energy intake, showed that individuals in higher categories of severity of obesity tended to have higher prevalence ratios of most cardiometabolic risk factors compared with the other weight groups, except for high fasting blood glucose among boys. CONCLUSIONS Progressive degrees of excess weight are positively associated with cardiometabolic risk factors in youth from a middle-income country, indicating the importance in classifying the severity of weight excess among adolescents and considering this to plan prevention programs against early development of obesity-related diseases. BACKGROUND The impact of high distraction, real-world environments on dual-task interference and flexibility of attentional prioritization during dual-task walking in people with stroke is unknown. RESEARCH QUESTION How does a real-world environment affect dual-task performance and flexible task prioritization during dual-task walking in adults with and without stroke? METHODS Adults with stroke (n = 29) as well as age-, gender-, and education-matched adults without stroke (n = 23) participated. Single and dual-task walking were examined in two different environments (lab hallway, hospital lobby). Two different dual-task combinations were assessed (Stroop-gait, speech-gait). Each dual-task was performed first without explicit instruction about task prioritization (no-priority) and then with gait-priority instruction and Stroop/speech-priority instruction in randomized order. RESULTS People with stroke had significantly slower dual-task gait speed (Stroop only) in the lobby than the lab, but the effect was nott may also be that the cognitive control strategy governing task prioritization is influenced by degree of cognitive engagement. BACKGROUND In 1872, Eadweard Muybridge was hired to research unsupported transit in horses, i.e. the trot and the gallop. This research was the first instance of the use of photography to analyse movement and was the ultimate precursor to motion capture for biomechanical assessment of movement utilised today. With the expansion of the field continuing, the term "gait" has become synonymous with walking and is often used interchangeably. In this editorial, we discuss the term "gait" and its' origin in the context of scientific research and aim to address the heterogeneous taxonomy associated with the ambiguous use of the term "gait". RESEARCH QUESTION What is the ambiguous use of the term gait? METHODS A non-systematic review was conducted of the original research and short communications in the 2019 issues of Gait and Posture RESULTS A total of 219 titles were characterised as directly addressing locomotion. Of these, a total of 108 titles quantified the form of locomotion (e.g. walk/ing, run/ing) and 111 titles utilised the word "gait" to describe the task. However, 104 of these clarified the form of locomotion either within the abstract or the main text of the manuscript. SIGNIFICANCE "Gait" is not mutually exclusive to humans nor walking. The ambiguity associated with the use of this term demonstrates the importance of quantifying the type of locomotion being studied. Ultimately, such efforts will allow the streamlining search strategies for appropriate research for academics, clinicians, and scientists alike. OBJECTIVES The proliferative activity of the Ki-67 index is important in decision-making of adjuvant treatments in early breast cancer. Its reliability can be reduced by inter-observer variability. This analysis' objective is to evaluate the robustness of Ki-67 values within one center over 5 years and to compare its distribution with a published dataset. MATERIALS AND METHODS Ki-67 indices of early breast cancers treated at St. Gallen Breast Center were collected (2010-2014; 1154 patients). Distribution of Ki-67 values was analyzed for each year, along with histologic subtype and grading. Tumors were classified into intrinsic subtypes using two definitions 2013 St. Gallen Consensus and the refined definition by Maisonneuve ("Milano Group"). Our institution's Ki-67 cut-off value was adjusted to obtain the same distribution of luminal subtypes as published data of the Milano Group. RESULTS Ki-67 index frequency distributions were comparable between years (mean 26-30%, median 22-26%). 2,4-Thiazolidinedione Shape and position of the distribution curves were nearly identical. Ki-67 values correlated with tumor grade (median Ki-67 G1 12.0%, G2 21%, G3 38%). Standard deviation of Ki-67 increased with higher grading (G1 6.9; G2 9.2; G3 18.2; p  less then  0.001). According to the 2013 definition (and refined definition respectively), there were 35% (41%) luminal A-like and 65% (59%) luminal B-like tumors. To obtain the same distribution as the Milano group, Ki-67 cut-off needed to be elevated to 22%. CONCLUSIONS Ki-67 index assessment was comparable over many years. Knowledge of one's institution's Ki-67 value distribution is essential for clinical decision-making of adjuvant therapies in early breast cancer.

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