Cooneybutler7105

en undergoing ART may need to focus on improving the skills of adaptive coping strategies.

To examine the safety and feasibility of total laparoscopic retrograde hysterectomy (TLreH) in patients with obliterated cul-de-sac due to severe endometriosis.

This retrospective case-control observational study was performed at the Yokohama Municipal Citizen's Hospital between January 2014 and December 2019. Ninety-two women who underwent TLreH and who had uterine fibroids, adenomyosis, or both with obliterated cul-de-sac due to severe endometriosis were enrolled.

Surgical outcomes were retrospectively analyzed. The median operation time was 122 (range, 54-312) min, and the median blood loss was 150 (range, 0-1420) mL. Perioperative complications (Clavien-Dindo classification ≥Ⅲ) occurred in 3 cases (3.3 %). There were no cases of transition to open surgery. Blood transfusion was required in 1 case. The operation time and estimated blood loss volume were significantly correlated with the weight of the uterus (p < 0.01). The subjects were divided into two groups uteri weighing ≥600 g group and those weighing <600 g group. In the ≥600 g group, the median operation time and median estimated blood loss volume were 130 (81-312) min and 265 (70-1420) mL, respectively. There was no difference in the frequency of perioperative complications or blood transfusions between the groups.

Our study demonstrated that TLreH for severe endometriosis with obliterated cul-de-sac was feasible and safe. It could be safely performed for large uteri (≥600 g) with obliterated cul-de-sac due to severe endometriosis.

Our study demonstrated that TLreH for severe endometriosis with obliterated cul-de-sac was feasible and safe. It could be safely performed for large uteri (≥600 g) with obliterated cul-de-sac due to severe endometriosis.

Vulvar Lichen sclerosus (LS) is a chronic inflammatory disease in which architectural changes and symptoms like itching, soreness, pain and dyspareunia can affect quality of life and sexual activity. Perineoplasty has been shown to be effective as a supportive surgical treatment in women with refractory dyspareunia in addition to the standard topical immunosuppressive treatment. The aim of this study was to evaluate retrospectively general complaints, patient satisfaction concerning sexual activity, reduction of dyspareunia/apareunia, orgasm ability and recurrence of LS after perineoplasty.

This study is a retrospective monocentric observational study, in which patients with vulvar LS who had undergone perineoplasty were invited to fill out a standardized questionnaire during the follow-up time. The main outcome measure is the overall patient satisfaction after surgical therapy of vulvar LS.

Forty-one of the 70 invited patients with a median age at surgery of 58 years (18-74 years) and a median 60 yearswed that perineoplasty is a safe surgical treatment option with a high satisfaction rate in patients with dyspareunia due to LS and a desire to regain sexual activity. Perineoplasty can improve sexual activity and achieve overall satisfaction in selected patients even though the recurrence rate of LS in sexually active patients remains high.

Magnetic resonance imaging (MRI) scores have been well validated in moderate/severe hypoxic-ischemic encephalopathy (HIE). Infants with mild HIE can have different patterns of injury, yet different scores have not been compared in this group of infants. Our objective was to compare the ability of three = MRI scores to detect abnormalities in infants with mild HIE, and infants with moderate/severe HIE were included for comparison.

This is a single-center prospective cohort study of infants ≥36weeks' gestation with HIE born at a level III neonatal intensive care unit from 2017 to 2019. All infants with HIE underwent an MRI, but only infants with moderate/severe HIE underwent therapeutic hypothermia. At least two experienced MRI readers who were unaware of all clinical variables independently assigned three scores (Barkovich, NICHD NRN, and Weeke).

A total of 42 newborns with varying HIE severity underwent MRI on day five of life. In the overall cohort, abnormalities were reported in three (7%) infants using the Barkovich, in 10 (24%) using the NICHD NRN, and in 24 (57%) using the Weeke score. Agreement was excellent for each score Barkovich score (k=1.0), NICHD NRN (k=0.92), and Weeke score (k=0.9).

Subtle injury due to mild HIE was detected with the highest frequency using the Weeke score, while inter-rater reliability was excellent for all three scores. These findings suggest that infants with mild HIE and subtle MRI abnormalities may benefit from detailed scoring systems, which is important for studies investigating the benefit of hypothermia in mild HIE.

Subtle injury due to mild HIE was detected with the highest frequency using the Weeke score, while inter-rater reliability was excellent for all three scores. These findings suggest that infants with mild HIE and subtle MRI abnormalities may benefit from detailed scoring systems, which is important for studies investigating the benefit of hypothermia in mild HIE.

Children with Down Syndrome (DS) have a high prevalence of obstructive sleep apnoea (OSA). selleck products Non-respiratory sleep disorders also occur commonly but are less well recognised. This cross-sectional study evaluates the prevalence of sleep difficulties in a community sample of Australian children with DS (DS

), using the Children's Sleep Habits Questionnaire (CSHQ), and compares them to children referred to the sleep clinic (DS

). To our knowledge this is the first study to have reported prevalence of sleep problems in Australian children with DS and to compare a community and referred group of children with DS directly.

The CSHQ was completed by parents of children with DS recruited from the community (DS

) via survey distributed by Down syndrome Queensland and Australia. A second group was recruited through the tertiary sleep clinic at our institution (DS

) and completed the same questionnaire on enrolment. Data from these groups was compared.

There were 76 participants in the DS

group (57% male; median age 9.