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significantly lower the overall risk of DSC. However, the reduction rate for specific cancers may vary. In addition, limited evidence suggests that meeting the international PA guidelines might not significantly reduce the risk of DSC. Thus, future studies must be conducted to determine the optimal dosage, frequency, intensity, and duration of PA required to reduce DSC risk effectively.

There has been an increasing focus on the importance of national policy to address population levels of physical inactivity. It has been suggested that the 4 cornerstones of policy comprise (1) national guidelines on physical activity (PA), (2) setting population goals and targets, (3) surveillance or health-monitoring systems, and (4) public education. see more The current study aimed to review the policy actions that have addressed each of these elements for children and youth in England and to identify areas of progress and remaining challenges.

A literature search was undertaken to identify past and present documents relevant to PA policy for children and youth in England. Each document was analysed to identify content relevant to the 4 cornerstones of policy.

Physical activity guidelines (Cornerstone 1) for children and youth have been in place since 1998 and reviewed periodically. Physical activity targets (Cornerstone 2) have focussed on the provision of opportunities for PA, mainly through physical educaincrease PA and reduce sedentary behavior.

There have been many developments in national PA policy in England targeted to children and young people. The area of most significant progress is national PA guidelines. Establishing prevalence targets, streamlining surveillance systems, and investing in public education with supportive policies, environments, and opportunities would strengthen national policy efforts to increase PA and reduce sedentary behavior.

Readmissions for patients with heart failure (HF) continues to be a target of value-based purchasing initiatives. Do-not-resuscitate (DNR) orders-one part of advance care planning (ACP)-have been shown to be related to other patient outcomes but has not been explored as a risk factor for HF readmission.

Examine the association between DNR and 30-day readmissions among elderly patients with HF admitted to hospitals in Pennsylvania.

Data included hospital discharges from 2011 to 2014 of patients 65+ years with a primary diagnosis of HF. Logistic regression was used to model the relationship between DNR and 30-day readmission.

Among 107,806 patients, 20.9% were readmitted within 30 days. After controlling for covariates, patients with HF who had a DNR were less likely to be readmitted to the hospital (OR=0.85, 95% CI 0.80-0.91, p<0.001).

Documentation of a DNR may inform efforts to reduce readmissions among elderly patients with HF.

Documentation of a DNR may inform efforts to reduce readmissions among elderly patients with HF.

As the Coronavirus disease 2019 (COVID-19) pandemic accelerates, our hospitals have become overwhelmed.

To describe detection of COVID-19 in asymptomatic hospitalized individuals awaiting advanced therapies for HF and the management of complications of COVID-19.

We present a unique case report of hospital-acquired COVID-19 in a patient on temporary mechanical circulatory support.

Despite intensive care and monitoring, he developed rapid progression of hypoxic respiratory failure which led to his death.

This case highlights various considerations for a patient with temporary MCS. It illustrates the high risk for development of COVID-19 for vulnerable hospitalized patients.

This case highlights various considerations for a patient with temporary MCS. It illustrates the high risk for development of COVID-19 for vulnerable hospitalized patients.

Among Left Ventricular Assist Device (LVAD) implanted patients, body image modifications might occur.

To explore the associations between sexual functioning, confidence in LVAD technology, personal wellbeing, and body image.

The cross-sectional study included 30 conveniently recruited LVAD implanted patients who completed Body Image Scale, sexual functioning, confidence in LVAD technology, and Personal Wellbeing Index questionnaires. The associations between the research variables were examined with multiple regression analyses.

The mean age of the participants was 63 (SD=10), 90% were men. The mean scores were sexual functioning - 2.43 (SD=1.20, range 1-5); confidence in LVAD technology - 2.63 (SD=1.04, range 1-5); Well-Being Index - 6.61 (SD=1.53, range 0-10); and body image - 14.5 (SD=4.17, range 5-20). Sexual functioning (p<.01) and LVAD technology confidence (p=.04) significantly predicted body image.

Healthcare professionals should be aware of challenges regarding body image faced by LVAD implanted patients and to address related factors.

Healthcare professionals should be aware of challenges regarding body image faced by LVAD implanted patients and to address related factors.

Similar to six-minute walk test (6MWT), sit-to-stand test (STST) is a self-paced test which elicits sub-maximal effort; therefore, it is suggested as an alternative measurement for functional exercise capacity in various pulmonary conditions including COPD and cystic fibrosis. We aimed to investigate the association between 30-second STST (30s-STST) and 6MWT in both children with bronchiectasis (BE) and their healthy counterparts, as well as exploring cardiorespiratory burden and discriminative properties of both tests.

Sixty children (6 to 18-year-old) diagnosed with non-cystic fibrosis BE and 20 age-matched healthy controls were included. Both groups performed 30s-STST and 6MWT. Test results, and heart rate, SpO

and dyspnea responses to tests were recorded.

Univariate analysis revealed that 30s-STST was able to explain 52% of variance in 6MWT (r=0.718, p<0.001) in BE group, whereas 20% of variance in healthy controls (r=0.453, p=0.045). 6MWT elicited higher changes in heart rate and dyspnea level compared to 30s-STST, indicating it was more physically demanding. Both 30s-STST (21.65±5.28vs 26.55±3.56 repetitions) and 6MWT (538±85vs 596±54m) were significantly lower in BE group compared to healthy controls (p<0.01). Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve (UAC) of 0.765 for 30s-STST and 0.693 for 6MWT in identifying the individuals with or without BE (p<0.05). Comparison between AUCs of 30s-STST and 6MWT yielded no significant difference (p=0.466), indicating both tests had similar discriminative properties.

30s-STST is found to be a valid alternative measurement for functional exercise capacity in children with BE.

30s-STST is found to be a valid alternative measurement for functional exercise capacity in children with BE.