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ObjectiveThe aim of this study is to investigate the effect of modified uvulopalatopharyngoplasty （UPPP） combined with endoscopic hypothermic Plasma glossectomy （Eco-TBR） on the severe Obstructive sleep apnea syndrome. MethodSixty patients with severe OSAHS were diagnosed by polysomnography, and their obstructive plane located in the oropharynx and tongue base. Patients were divided into the control group （30 cases of simple H-UPPP） and the experimental group （30 cases of H-UPPP combined with Eco-TBR） according to their random hospital sequence. SPSS 20.0 software package was used to analyze the preoperative and postoperative data of the two groups. ResultFifty-seven OSAHS patients had full data and a minimum 6 month follow up to assess the efficacy. The total effective rate in the control group was 41.38% lower than that in the experimental group 67.85%, and the difference was statistically significant （χ²=4.03, P0.05）. ConclusionThe effect of H-UPPP combined with Eco-TBR on severe OSAHS patients with obstructive plane of oropharynx and tongue root is definite.ObjectiveTo evaluate the value of improved Mallampati grading combined with NoSAS questionnaire in screening for obstructive sleep apnea （OSA）. MethodA total of 344 patients admitted to our hospital for sleep disorders were studied. All patients were measured for their height, weight, neck circumference and other parameters. NoSAS scores, improved Mallampati grading and polysomnography （PSG） were performed in these patients. According to AHI in PSG monitoring results, patients were divided into non-osa group （AHI30） according to the PSG result. The ROC curve was plotted to evaluate the screening value of NoSAS and improved Mallampati grading combined with NoSAS for OSA. ResultWith the NoSAS score of 8 or 9 as cutoffs for analysis, the sensitivity for OSA was 0.733 and 0.701; the specificity for OSA was 0.538 and 0.624, respectively. The sensitivity and specificity of NoSAS combined with improved Mallampati grading for screening OSA were 0.813 and 0.710, respectively. ConclusionAs a new screening tool, NoSAS questionnaire is simple and convenient, and has certain screening value to OSA. The improved Mallampati grading combined with NoSAS questionnaire can obviously improve the screening sensitivity and specificity of Osa, and has higher application value.ObjectiveTo compare the efficacy of cochlear implantation in deaf patients with Mondini malformation and normal anatomical structure of inner ear, and to determine whether cochlear implantation can be an effective way to reconstruct hearing in hearing loss patients with Mondini malformation, so as to guide clinical work. MethodLiterature search was conducted on PubMed, YZ365. com, Wip medicine, Wanfang data, CHKD, CNKI and other electronic databases to search case control studies on postoperative rehabilitation effect of deafness patients with Mondini deformity and normal structure of inner ear. Execute Meta-analysis by using RevMan 5.3 software. ResultEleven articles were included and 1 371 patients were involved. Meta-analysis showed that the probability of Mondini abnormalities in patients with intraoperative complications（Z=6.62, P0.05） there was no statistically significant difference with the control group. ConclusionCochlear implantation can be a mean of treatment and rehabilitation for deafness patients with Mondini deformity, and is necessary for hearing reconstruction. Further multi-parameter controlled studies with longer follow-up periods and larger samples will increase the credibility for the efficacy of cochlear implants in deafness patients with Mondini malformation.ObjectiveTo investigate the distribution of allergens in patients with allergic rhinitis（AR） in Rikaze. MethodA retrospective analysis was performed in patients with AR diagnosed by skin prick test （SPT） between June 2017 and June 2018 from Rikaze People's Hospital. ResultOne hundred and thirty-one patients were diagnosed with AR using SPT. The most common inhalant allergens were pollen, including Artemisia sieversiana willd（64.8%）, Artemisia annua L. （64.1%） and Humulus Scandens（45.8%）, while soybean（17.6%）, mango（15.3%） and carp（12.2%） were the most common food allergens. ConclusionThe most common inhalant allergens in patients with AR is the pollen in Rikaze area.ObjectiveTo analyze the correlation between the modified nasal endoscopic score and ELR value and the subtype of chronic sinusitis with nasal polyps. MethodThe clinical data of 119 patients of chronic sinusitis with nasal polyps were retrospectively analyzed. click here According to the postoperative pathological results, they were divided into two groups eosinophilic chronic sinusitis with nasal polyps（eCRSwNP） and non-eosinophilic chronic sinusitis with nasal polyps（neCRSwNP）. All patients underwent modified nasal endoscopic examination scores, according to clinical features and anatomical features into the part of the middle nasal meatus and the part of olfactory fissure, and the scores were calculated in two areas respectively; History of asthma, allergic rhinitis and the percentage of eosinophils（EO%）, the absolute value of eosinophils（EO#）, the absolute neutrophil（N）, the absolute lymphocyte（R）, the total IgE were recorded at the same time. Calculate the NLR value and ELR value. This study used SPSS 19.0 for statistical analysis of relevant data. ResultAccording to the modified nasal endoscopic scoring criteria, the eCRSwNP group had significantly higher olfactory fissure area scores while middle nasal meatus area scores were significantly lower than the neCRSwNP group; ELR value, EO% and EO# were significantly higher in the eCRSwNP group than in the control group, while NLR value and N value were higher in the neCRSwNP group（P less then 0.05）; There was no significant difference in age, gender, R value and total IgE between the two groups. Compared with EO#, the ELR value was more stability and sensitivity. Therefore, the olfactory fissure area polyps and ELR value are more significant for pre-diagnosis. ConclusionThe modified nasal endoscopic score and ELR value are more correlated with the subtype of CRSwNP. Higher ELR value ,lower NLR value, and association with allergic rhinitis, asthma can be used as prediagnostic indicators for eCRSwNP before invasive pathological results and CT examination.