Cantrellbass2215

Introduction Coronavirus disease 2019 (COVID-19) resulted in many health care workers across the country being redeployed to different clinical roles. This study aimed to evaluate the unique experience of team members in our health system from clinical informatics who were redeployed to provide emergency telehealth care in a clinical role. Methods Clinical informatics team members were redeployed during the first month of the pandemic onset in March 2020 to a clinic providing virtual screening for COVID-19. Participants completed an anonymous survey after 90 days. Results During the study period, 76 clinical informatics team members provided telehealth and 85.3% of those eligible responded to the survey. Respondents felt prepared with clinical protocols and technical tools. The most common stressors were rapidly changing clinical protocols. Participants enjoyed the chance to work with patients and aiding during a pandemic. Conclusions Clinical informatics team members redeployed to a virtual care screening hub endorsed positive experiences and the majority said that they would provide virtual care again. This experience gave important insights on how informatics skills can aid in a rapid coordinated telehealth response.

There is a large body of research indicating that substance use disorder treatment completion leads to higher rates of sustained recovery. However, not much is known about how age and opioid treatment programs (OTPs) OTPinteract to affect treatment completion. The purpose of this article is to better understand the pathway between age, OTP, and treatment completion.

Data from the US 2017 Treatment Episodes Data Set was analyzed. Seemingly unrelated bivariate probit regression was used to determine whether OTP access mediates the relationship between age and treatment completion. We used propensity score matching to simulate the effects of a randomized control trial and to attenuate the likelihood of a Type 1 error.

Older adults have a higher likelihood than their younger counterparts of completing treatment regardless of OTP status in inpatient and outpatient settings. Those who received OTP in inpatient treatment had a 45% increased probability of completing treatment in detox settings and a 41% increased probability of completing treatment in inpatient settings. Older adults (age 50+) were more likely to receive OTP than their younger counterparts. There is a small but significant indirect effect of age on treatment completion in inpatient settings.

Older adults are more likely to receive OTP in both inpatient and outpatient settings. However, age does not appear to affect the probability of treatment completion when individuals receive OTP, except in inpatient settings. Implications are discussed.

Older adults are more likely to receive OTP in both inpatient and outpatient settings. However, age does not appear to affect the probability of treatment completion when individuals receive OTP, except in inpatient settings. Implications are discussed.Background During the COVID-19 pandemic telemedicine was rapidly expanded and incorporated into day-to-day practice by primary care providers to allow continued access to care for patients during this time. The quick adoption of telemedicine occurred out of necessity for social distancing, and evidence-based approaches are needed to determine the future utility of this approach to delivering care. The objective of this study was to identify factors associated with both provider and patient satisfaction with telemedicine visits in a primary care setting during the COVID-19 pandemic. Method This survey-based study was conducted in 2020. Surveys were distributed electronically by e-mail to providers and patients. Participants Surveys related to satisfaction levels with telemedicine were distributed to 73 primary care providers and 6,626 patients. Main Outcomes and Measures The primary measures of this study were satisfaction level with telemedicine in primary care. Results Studies were completed by 23 primary cawere less likely to be satisfied than those that had Zoom© visits.This review focuses on the literature published during the calendar year 2020 that is of interest to anesthesiologists taking care of children and adults with congenital heart disease. Five major themes are discussed, including COVID-19 in children with heart disease, race and outcome disparities in congenital heart disease, Norwood procedure and outcomes, Fontan procedure and outcomes, and neurotoxicity/neurologic outcomes. A total of 59 peer-reviewed articles are discussed.Introduction The COVID-19 pandemic accelerated telehealth to deliver psychiatric services. Continuation of psychiatric services for individuals with high clinical acuity was critical. This study examined attendance to rapidly deployed telehealth services for psychiatrically high-risk individuals receiving intensive outpatient program (IOP), primarily group-based psychotherapy services for adults and adolescents by race/ethnicity, insurance, and clinical treatment program within a large hospital-based outpatient psychiatric setting. selleck kinase inhibitor Methods Chi-square tests compared whether attendance rates for telehealth versus in-person IOP services varied by population group, race, insurance, and clinical program, using observational data of adolescent and adult patients treated between October 1, 2019, and July 31, 2020. Results Appointment attendance increased for telehealth versus in-person services for adolescents (χ2 (df = 1) = 27.49, p less then 0.0001) and adults (χ2 (df = 1) = 434.37, p less then 0.0001). For adinvestigation regarding the potential for special challenges or vulnerabilities and advocacy needs. Findings highlight telehealth as an important tool in supporting availability of services for individuals with high levels of psychiatric acuity, particularly for group-based services, during the pandemic.Objective We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).Methods From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies.Results Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI 0.89, 1.09; I2 = 0.00%).Conclusion MS is not associated with PE.Circulating tumor DNA (ctDNA), a fraction of cell-free DNA (cfDNA) in the circulatory system, is released from tumor cells and thus carries tumor-specific genetic signatures. Using blood-derived ctDNA to detect somatic mutations has shown great value in guiding cancer targeted therapy. Isolation and detection efficiencies are the key factors affecting the performance of ctDNA detection. To optimize and standardize our clinical practice, in this study, we analyzed the isolation efficiency of four commercial cfDNA purification kits QIAamp circulating nucleic acid kit, AmoyDx® Circulating DNA kits, Microdiag® circulating DNA isolation kit, and MagMAX cell-free DNA isolation kit; and the detection efficiency of two mainstream domestic EGFR gene mutation detection kits MicroDiag EGFR gene mutation detection kit and Fluorometric real-time PCR Detection Kit for the analysis of EGFR gene mutations. Reference materials and plasma samples collected from lung cancer patients and healthy volunteers were used for the analysis. Our results showed that QIAamp circulating nucleic acid kit and Microdiag® circulating DNA kit had the highest recovery rate (up to 21.25 ng/mL) for short DNA fragments of about 173 bp which is the peak length of ctDNA. For ctDNA detection, the MicroDiag® EGFR gene mutation detection kit showed the highest detection rate and sensitivity for detecting EGFR mutations at a mutant frequency of 0.5%. This work provides a reliable choice of commercial kits for the clinical application of ctDNA.

To analyze how ophthalmic drugs fared in the early benefit assessment (EBA) after its introduction in Germany up to 2020 and to quantify its impact on their negotiated prices.

Relevant documents were screened and essential content on added benefit outcomes and the underlying evidence was extracted next to pricing information. In addition to descriptive statistics, cross-stakeholder analyses and agreement statistics were implemented.

Thirteen completed EBA were identified involving eight drugs. Only four drugs (30.8%) received an added benefit. The OR for no added benefit of ophthalmic drugs versus all other drugs was 2.971 (0.902-9.781). The agreement between manufacturers' claims and decision-maker appraisals is fair (kappa 0.435). In all cases, evidence was derived for RCTs, but for different reasons, not all of them allowed direct comparisons with the comparator as defined by the decision-maker. The negotiated rebates on manufacturer's selling prices varied from 6.8% up to 47.4%. Nevertheless, the rebates for ophthalmic drugs (median 14.5%) were lower than those for all negotiated drugs (median 24%).

Over the past decade, the EBA of ophthalmic drugs was not necessarily a success story, but in most of the cases, the drugs were successful in the market.

Over the past decade, the EBA of ophthalmic drugs was not necessarily a success story, but in most of the cases, the drugs were successful in the market.Objective The purpose of this review is to systematically assess the existing literature and summarize the evidence regarding the effect of erbium-doped yttrium aluminum garnet (ErYAG) laser on enamel surface roughness and pulp health compared with the conventional orthodontic debonding techniques. Materials and methods Following the preferred reporting items for systematic reviews (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement, the electronic database, PubMed, Scopus, Web of Science, Google scholar, and Saudi Digital Library were searched for relevant published records. Data were collected following specific keywords "debonding" "ErYAG laser" etc. In vitro studies, and clinical randomized- and nonrandomized-controlled studies limited to the English language and published in peer-reviewed journals were included. Results A total of 564 articles were identified as relevant to the topic. Duplicates were excluded resulting in 382 articles, out of which 374 articles were discarded upon screening titles and abstracts. The remaining eight articles were read to their entirety and included in the current qualitative review after fulfilling the eligibility criteria. In all the included studies, a total of 480 sound posterior teeth were used to evaluate the effect of ErYAG laser on debonding of orthodontic brackets from the enamel surface. Conclusions ErYAG laser debonding has demonstrated a reduced risk of enamel damage (fracture or cracks) but resulted in increased enamel surface roughness and was time-consuming for adhesive removal procedures compared with the conventional debonding methods. Further, within the applied laser settings, ErYAG lasers have found to exhibit low thermal exhaustion in relation to the pulp. The laser source with a wavelength of 2940 nm has been used with different setting ranges (power of 2.5-5 W, energy 125-600 mJ, frequency 4-30 Hz, and pulse duration 50-350 μsec) for debonding of orthodontic brackets.