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In contrast, no difference was detected in growth performance. Significant positive correlations between the cortisol level and serotonergic activity were observed in the short-term contest, but the serotonergic activity was negatively correlated with the aggressive behavior in the long-term contest. These results suggest that subordinate hierarchy inhibits aggression but does not impact growth in black rockfish. The cortisol-related change in brain monoaminergic activity could be a potential indicator to predict aggressive behavior in black rockfish in captivity with an obvious social hierarchy.The developmental psychopathology clinical and theoretical framework has proposed a bio-psycho-social model that integrates biological, environmental, social, and psychological factors to disentangle the underpinning mechanisms of the intergenerational transmission of psychopathological risk [...].Control of Theileria equi, the primary cause of equine theileriosis, is largely reliant on acaracide use and chemosterilization with imidocarb dipropionate (ID). However, it is currently unknown if ID is effective against Theileria haneyi, the recently identified second causative agent of equine theileriosis, or if the drug maintains effectiveness against T. equi in the presence of T. haneyi co-infection. The purpose of this study was to address these questions using ID treatment of the following three groups of horses (1) five T. haneyi infected horses; (2) three T. haneyi-T. equi infected horses; and (3) three T. equi-T. haneyi infected horses. Clearance was first evaluated using nPCR for each Theileria sp. on peripheral blood samples. ID failed to clear T. haneyi in all three groups of horses, and failed to clear T. equi in two of three horses in group two. For definitive confirmation of infection status, horses in groups two and three underwent splenectomy post-treatment. The T. equi-nPCR-positive horses in group two developed severe clinical signs and were euthanized. Remaining horses exhibited moderate signs consistent with T. haneyi. Our results demonstrate that ID therapy lacks efficacy against T. haneyi, and T. haneyi-T. equi co-infection may interfere with ID clearance of T. equi.Disposable electronic cigarettes (e-cigarettes) became popular among youth after the Food and Drug Administration (FDA) implemented an enforcement policy to restrict the sale of cartridge-based flavored e-cigarettes starting from February 2020 in the United States (US). We aimed to examine the flavors and topics related to disposable e-cigarettes on Twitter. The Twitter dataset, which includes 1489 tweets, was collected by the Tweepy streamapplication programming interface (API) using a keyword query from March to September 2020. The disposable e-cigarette flavors were curated from both online stores and collected tweets. Topics related to disposable e-cigarettes on Twitter were manually coded. Distributions of topics were compared between tweets from the US and tweets from non-US countries. The temporal analysis results showed a slight increase in the number of discussions over the study period. Strawberry, mango, watermelon, and mint were the most popular flavors of disposable e-cigarettes mentioned on Twitter. Almost all the tweets (97.11%) were commercial tweets, which were dominated by topics related to the product and flavor promotions. The US tweets focused more on product and flavor promotions and less on price promotions compared to non-US tweets. Our results suggest that companies exploited the limitations of legislation to promote flavors on Twitter, which could undermine public health and young people's finances if they get hooked on addictive products.Decellularized tissue is an important source for biological tissue engineering. Evaluation of the quality of decellularized tissue is performed using scanned images of hematoxylin-eosin stained (H&E) tissue sections and is usually dependent on the observer. The first step in creating a tool for the assessment of the quality of the liver scaffold without observer bias is the automatic segmentation of the whole slide image into three classes the background, intralobular area, and extralobular area. Such segmentation enables to perform the texture analysis in the intralobular area of the liver scaffold, which is crucial part in the recellularization procedure. Existing semi-automatic methods for general segmentation (i.e., thresholding, watershed, etc.) do not meet the quality requirements. Moreover, there are no methods available to solve this task automatically. Given the low amount of training data, we proposed a two-stage method. The first stage is based on classification of simple hand-crafted descriptors of the pixels and their neighborhoods. This method is trained on partially annotated data. Its outputs are used for training of the second-stage approach, which is based on a convolutional neural network (CNN). Our architecture inspired by U-Net reaches very promising results, despite a very low amount of the training data. Picropodophyllin price We provide qualitative and quantitative data for both stages. With the best training setup, we reach 90.70% recognition accuracy.In this paper, we propose a solvent-free device fabrication method using a melt-blown (MB) fiber to minimize potential chemical and thermal damages to transition-metal-dichalcogenides (TMDCs)-based semiconductor channel. The fabrication process is composed of three steps; (1) MB fibers alignment as a shadow mask, (2) metal deposition, and (3) lifting-up MB fibers. The resulting WSe2-based p-type metal-oxide-semiconductor (PMOS) device shows an ON/OFF current ratio of ~2 × 105 (ON current of ~-40 µA) and a remarkable linear hole mobility of ~205 cm2/V·s at a drain voltage of -0.1 V. These results can be a strong evidence supporting that this MB fiber-assisted device fabrication can effectively suppress materials damage by minimizing chemical and thermal exposures. Followed by an MoS2-based n-type MOS (NMOS) device demonstration, a complementary MOS (CMOS) inverter circuit application was successfully implemented, consisted of an MoS2 NMOS and a WSe2 PMOS as a load and a driver transistor, respectively. This MB fiber-based device fabrication can be a promising method for future electronics based on chemically reactive or thermally vulnerable materials.

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