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To determine the extent of radiant exposure (RE) attenuation of three LED light-polymerization units (LPUs), and their beam-profile, at the bottom of the Class-2 slot, using MARC-PS.

10 seconds RE was delivered to MARC-PS' anterior sensor by Bluephase-Style, Demi-Plus, and Deep-Cure-S. Two ivorine lower first-molars received Class-2 proximal box preparations (3×2×4 mm and 4×4×4 mm) and were sectioned horizontally above the cementoenamel junction. Tofflemire matrix-retainer was placed around each tooth and secured with a low-fusing compound. Each LPU tested delivered 10 seconds RE to MARC-PS through proximal slots. Lanraplenib in vivo Mean RE of three readings per group was obtained. Data were analyzed using Pearson correlation, mixed ANOVAs with a pre-set alpha of 0.05.

RE attenuation ratio calculated from the baseline to 4× 4×4/3×2×4 Class-2 boxes were 58.25/80.03 Bluephase-Style; 49.36/80.25 Demi-Plus; 32.8/77.43 Deep-Cure-S. A significant and strong correlation (r= 0.86, P< 0.001) between the reduction in aperture size and RE was found. The beam profile of LED-LPUs tested decreased RE values at the bottom of a proximal box. More than 80% RE value reduction from the baseline to the smallest Class-2 cavity 3×2×4 aperture was observed.

Polymerization of resin-composites at the bottom of the Class-2 box is challenging due to the small aperture size, depth, and hard-to-reach location. Inadequate polymerization at the bottom of the Class-2 proximal box is a causative factor for secondary caries and, ultimately, restoration failure.

Polymerization of resin-composites at the bottom of the Class-2 box is challenging due to the small aperture size, depth, and hard-to-reach location. Inadequate polymerization at the bottom of the Class-2 proximal box is a causative factor for secondary caries and, ultimately, restoration failure.

To evaluate the anti-gingivitis efficacy of two bioavailable stannous fluoride (SnF2) dentifrices versus a zinc/arginine dentifrice and a negative control dentifrice, and to compare the plaque control benefits.

This was a single-center, randomized, controlled, four-treatment, parallel-group, double-blind, 3-month clinical trial. Healthy adult subjects with gingivitis were randomly assigned to one of four different dentifrice treatment groups SnF2 dentifrice A, SnF2 (1,100 ppm F) + sodium fluoride (350 ppm F) + sodium hexametaphosphate (Procter & Gamble); SnF2 dentifrice B, SnF2 (1,100 ppm F) + sodium fluoride (350 ppm F) + citrate (Procter & Gamble); Zn/Arg dentifrice, zinc/arginine + sodium fluoride (1,450 ppm F) (Colgate-Palmolive); negative control dentifrice, sodium monofluoro-phosphate (1,000 ppm F) + sodium fluoride (450 ppm F) (Colgate-Palmolive). Subjects brushed with their assigned treatment dentifrice and an assigned manual toothbrush (Oral-B Indicator) for 1 minute, twice daily, for theifrice.

To evaluate the chemical composition and morphological properties of eroded dentin after biomodification with phosphorylated chitosan (P-Chi) and carbodiimide (EDC).

42 bovine dentin specimens were used; 21 of these specimens were subjected to erosive challenge with 0.3% citric acid (pH = 3.2) for 2 hours. The specimens were randomly divided into six groups according to dentin substrate (sound or eroded) and biomodification [with 2.5% P-Chi, with 0.5 mol/L EDC, or no biomodification (control)]. The specimens were analyzed by Fourier-transform infrared spectroscopy (FTIR, n= 5, in triplicate) and atomic force microscopy (AFM, n= 2) to verify the phosphate, carbonate, and organic matrix absorption peaks and to investigate surface morphology, respectively. The data were analyzed with Origin 6.0.

Dentin erosion reduced the intensity of the phosphate (1,100 cm⁻¹) and carbonate (872 cm⁻¹) related bands, which evidenced demineralization. Eroded dentin consisted of a more irregular surface containing slightly mth surfaces and to improve the adhesive interface.

To evaluate and describe the most frequent TMJ degenerative bone alterations on MRI and CT and to determine the accuracy, sensitivity, and specificity of MRI.

Images of 80 subjects were selected and evaluated from a database and 57 were selected. The subjects were submitted to CT and MRI exams (each subject on the same day). The joints were evaluated in the sagittal and coronal planes under closed mouth position. Each individual parameter was scored as absent or present. Absolute and relative frequencies were obtained and the Kappa concordance index test and equality of two proportions were used. To correlate the presence of bone alterations, the Chi-Square test was performed. A significance level of 0.05 (5%) was defined, with 95% of statistical confidence interval.

Of the 57 subjects, (47 female, 10 male), the ages ranged from 18-83 years (mean 43 years). The intra and inter-rater agreement tests demonstrated reliability among the examiners for all variables analyzed on MRI and CT.

MRI is a reliable and valid method for observing bone changes in the TMJ, with the advantage of non-exposure to radiation and cost-effectiveness due to the use of only one exam.

MRI is a reliable and valid method for observing bone changes in the TMJ, with the advantage of non-exposure to radiation and cost-effectiveness due to the use of only one exam.

This pilot study assessed the periodontal status and biomarkers of systemic inflammation in acute coronary syndrome (ACS) patients.

15 ACS patients on statin (anti-cholesterol) therapy, were recruited into the study an average of 9 months after discharge from university hospital. Blood and mouthrinse samples were collected for analysis of inflammatory biomarkers including high sensitivity C-reactive protein (hsCRP), IL-6, IL-1β, TNF-α, and MMP-9. Full-mouth periodontal examination, including pocket depth (PD), clinical attachment levels (CAL), bleeding on probing (BOP), and tooth mobility, was performed.

When their periodontal status was assessed by CAL, 100% of these statin-treated ACS patients exhibited moderate (66.7%) to severe (33.3%) periodontal disease, which appears to be higher than the rate described for the general adult population (i.e., 47% for periodontitis). In addition, (1) their blood hsCRP levels ranged from 0.94 to 12.6 mg/L with a mean of 3.41 mg/L, which is considered high risk for cardiovascular disease (CVD) in spite of their statin therapy, and (2) the data demonstrated a positive correlation between severe periodontitis and elevated blood hsCRP levels (P< 0.

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