Brittglerup1035

Each of the experts was responsible for reviewing a topic or question relevant to the topic. In a second phase, four experts discussed and structured the texts produced, and, in the last phase, all experts reviewed and approved the present manuscript and its recommendations.

To investigate the reliability, internal consistency and validity of the Brazilian Portuguese version of the University of California San Diego Shortness of Breath Questionnaire (UCSD SOBQ) in patients with interstitial lung disease (ILD).

Patients with ILD completed the questionnaire at three different time points, one week apart, with the assistance of two independent assessors. Intra- and inter-rater reliability were analysed via the intraclass correlation coefficient (ICC). Internal consistency was assessed with the Cronbach's alpha coefficient. For the validity analysis, associations between variables were assessed with Spearman's or Pearson's correlation coefficient.

Thirty patients with ILD (idiopathic pulmonary fibrosis, connective tissue disease-associated pulmonary fibrosis, sarcoidosis, asbestosis or non-specific interstitial pneumonia) were included (15 men; mean age, 59 ± 10 years; DLCO 46 [33-64] % predicted). UCSD SOBQ scores showed excellent agreement and internal consistency in the intra-rater analysis (ICC 0.93 [0.85-0.97]; Cronbach alpha 0.95) and in the inter-rater analysis (ICC 0.95 [0.89-0.97]; Cronbach alpha 0.95), as well as correlating significantly with dyspnoea (as assessed by the Medical Research Council scale; r = 0.56); Medical Outcomes Study 36-item Short-Form Health Survey domains bodily pain, general health, vitality and physical functioning (-0.40 ≤ r ≤ -0.74); six-minute walk distance (r = -0.38); and quadriceps muscle strength (r = -0.41).

The Brazilian Portuguese version of the UCSD SOBQ is valid, is reliable and has internal consistency in patients with ILD in Brazil.

The Brazilian Portuguese version of the UCSD SOBQ is valid, is reliable and has internal consistency in patients with ILD in Brazil.

Because SARS-CoV-2 infection can severely affect the lungs and persistent functional changes can occur after severe disease, we aimed to determine lung function parameters of COVID-19 patients at 45 days after hospital discharge and compare changes according to the severity of the disease.

This was a prospective descriptive analytical multicenter study. The participants were allocated into three groups ward admission (WA) group; ICU admission not on mechanical ventilation (ICU/MV-) group; and ICU admission on MV (ICU/MV+) group. Lung volumes, DLco, MIP, MEP, and six-minute walk distance (6MWD) were measured 45 days after discharge.

The sample comprised 242 patients (mean age = 59.4 ± 14.8 years; 52.1% of males), and 232 (96%) had altered lung function. In the total cohort, restrictive disorder was observed in 96%, as well as reductions in DLco (in 21.2% of the patients), FEV1/FVC (in 39.7%), and PEmax (in 95.8%), with no differences between the groups. Comparing the groups, the ICU/MV+ group had reduced DLco in 50% of the patients (p < 0.001) and a lower mean 6MWD % of the predicted value (p = 0.013). Oxygen desaturation in the six-minute walk test was observed in 32.3% of the cohort and was less frequent in the IE group.

This is the first South American study involving severe COVID-19 survivors whose lung function was assessed 45 days after hospital discharge. Changes were frequent, especially in those on MV, which highlights the importance of lung function evaluation after severe COVID-19.

This is the first South American study involving severe COVID-19 survivors whose lung function was assessed 45 days after hospital discharge. Changes were frequent, especially in those on MV, which highlights the importance of lung function evaluation after severe COVID-19.

To explore the predictive roles of D-dimer for the mortality of patients with community-acquired pneumonia (CAP).

This was a systematic review and meta-analysis. We searched the following databases PubMed, EMBASE, Web of Science, Ovid MEDLINE, and Cochrane Library from their inception to July 26, 2020. Studies exploring the relationship between blood D-dimer levels and CAP-related mortality were selected. In this meta-analysis, we calculated mortality rates, sensitivity, specificity, positive likelihood ratios, and negative likelihood ratios.

The search identified 1,073 articles, 8 of which (a total of 2,126 patients) were included in this meta-analysis. The pooled mortality rate of the overall sample was 0.10 (95% CI, 0.08-0.14). GW9662 mouse The levels of blood D-dimer in the nonsurvivors were significantly higher than those in the survivors (weighted mean difference = 1.03 mg/L [95% CI, 0.81-1.26]; p < 0.00001). The area under the summary ROC curve for the optimal cutoff value of D-dimer as a predictor of mortality was 0.848 (SE = 0.046), and the pooled negative likelihood ratio for D-dimer within the normal range was 0.24 (95% CI, 0.11-0.53).

Blood D-dimer might be helpful for the initial assessment of mortality risk of patients with CAP. D-dimer levels within the normal range indicate low risk of mortality. Because of the small sample size in our study, our findings should be further explored and validated in future studies with larger sample sizes.

Blood D-dimer might be helpful for the initial assessment of mortality risk of patients with CAP. D-dimer levels within the normal range indicate low risk of mortality. Because of the small sample size in our study, our findings should be further explored and validated in future studies with larger sample sizes.

The digital technology has contributed to improve and simplify diagnosis, treatment planning and execution in Orthodontics. Among CAD/CAM system (Computer-Aided Design / Computer-Aided Manufacturing) applications in Orthodontics, we highlight the installation and removal of fixed appliance, clear aligners, customized appliances, and retainers fabricated in digital environment. This approach has several advantages for practitioner and patient, as it enhances appliances precision, directly interferes in treatment time and predictability. Even with all the benefits arising from the digital workflow, few orthodontists have adopted this technique in their clinical practice, most due to high cost and lack of technical preparation for proper execution.

Thus, given the importance of digital technology to improve specialty performance and the still incipient incorporation of digital flow in Orthodontics, the purpose of this article is to describe the available resources and clinical applications of the CAD/CAM technology in Orthodontics.

Thus, given the importance of digital technology to improve specialty performance and the still incipient incorporation of digital flow in Orthodontics, the purpose of this article is to describe the available resources and clinical applications of the CAD/CAM technology in Orthodontics.

Assessment of two radiographic images reveals two distinct, extreme situations of physiological tooth resorption, characteristic of primary teeth with or without permanent successor, due to partial anodontia.

In all primary teeth, rhizolysis begins after the completion of formation, thanks to the apoptosis of their cells. When apoptosis induced by cementoblasts has denuded the root of these cells, the process of rhizolysis inevitably begins This will be accelerated by mediators arising from the pericoronal follicle. When there is no permanent successor due to partial anodontia, rhizolysis occurs extremely slowly, and months later, without the epithelial rests of Malassez that were dead due to apoptosis, alveolodental ankylosis becomes established, and the tooth will gradually be replaced by bone, still within a physiological context.

Rhizolysis and physiological tooth resorption may occur rapidly or slowly, early or late, and this depends on the presence of the permanent tooth, or its absence due to partial anodontia.

Rhizolysis and physiological tooth resorption may occur rapidly or slowly, early or late, and this depends on the presence of the permanent tooth, or its absence due to partial anodontia.

To evaluate the 3x3 bonded retainer influence on the mandibular anterior crowding in cases treated with mandibular incisor extraction.

The sample comprised pretreatment, posttreatment and follow-up orthodontic records of 16 subjects (10 females and 6 males) with Class I malocclusion treated with extraction of a single mandibular incisor. The mean ages (± SD) at pretreatment, posttreatment and follow-up evaluation were 23.45 ± 9.14 years, 25.50 ± 8.95 years and 30.11 ± 8.59 years, respectively. The mean (± SD) treatment time and posttreatment evaluation time were 2.05 ± 0.45 years and 4.60 ± 1.85 years , respectively. Little irregularity index and interdental widths were evaluated using dental casts. The sample was divided into two subgroups, according to the presence of the 3x3 bonded retainer at follow-up.

The subgroup without 3x3 bonded retainer presented a greater relapse at the follow-up, when compared to 3x3 bonded retainer subgroup.

There was a significant relapse in cases treated with mandibular incisor extraction at follow-up. The subgroup without 3x3 bonded retainer showed a significant relapse at the follow-up when compared to the retainer group.

There was a significant relapse in cases treated with mandibular incisor extraction at follow-up. The subgroup without 3x3 bonded retainer showed a significant relapse at the follow-up when compared to the retainer group.

This study evaluated the force decay and design shape changes caused by stress relaxation in two different orthodontic cantilever configurations.

Eighty cantilevers made of 0.017 x 0.025-in beta-titanium wires were standardized in a passive position, using real scale templates, and randomly divided into two groups (n = 40) Type 1 and Type 2. Each group received a different design (Type 1 with three bends, and Type 2 with two bends), and both were divided in four subgroups (n = 10) according to the evaluation periods G1 = 24h, G2 = 1 week, G3 = 4 weeks, and G4 = 8 weeks. Mechanical tests were performed immediately after preactivation and at the end of each period, to evaluate force decay. The cantilevers were also scanned and the angles of the bends were measured to assess shape changes.

Cantilever forces decayed over time. Type 1 - G1 showed less force decay than Type 2 (10.83 cN vs 17.87 cN). Type 1 cantilevers showed significant force decay only when G4 was compared to G1 (9.05 cN), G2 (11.73 cN), and G3 (9.78 cN). Type 2 cantilevers presented differences when G1 was compared to G2 (9.57 cN) and G3 (7.89 cN). Regarding to the cantilever angle closest to the bracket insertion, Type 1 cantilevers showed significant decrease for G2 (1.58°) and G4 (1.52°).

Cantilevers' design and proximity of the bends influenced force decay pattern overtime. Type 1 cantilevers presented more stable design at the first weeks than Type 2.

Cantilevers' design and proximity of the bends influenced force decay pattern overtime. Type 1 cantilevers presented more stable design at the first weeks than Type 2.

The vertical position of orthodontic brackets in maxillary incisors may influence the incisal step between the anterior teeth and thereby interfere with the smile esthetics. Even so, esthetic standards have been modified over time and consistently required technical adjustments.

This study analyzed orthodontists' preferences regarding the difference of bracket bonding height between the maxillary central incisors (MCI) and maxillary lateral incisors (MLI), and further determined whether the orthodontist sex, age and time of specialization have association to their choices.

This study collected data through an electronic form. Study participants analyzed a clinical case in which they indicated their preference for bracket bonding height. The placement height options ranged from 3.0 mm to 5.5 mm from the incisal edge, with 0.5-mm intervals, or at the clinical crown center (CCC). The difference in the bonding height between the MCI and MLI was analyzed, considering the formation of incisal steps between these teeth.