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Only the cases reported complain about the rigidity and, therefore, the possibility of fracture of the zirconium. Certainly the continuous improvement in these materials will ensure that they could be used safely while maintaining their high aesthetic performance.With the popularity of electric vehicles, the ever-increasing demand for high-capacity batteries highlights the need for monitoring the health status of batteries. In this article, we proposed a magnetic imaging technique (MIT) to investigate the health status of power batteries nondestructively. This technique is based on a magnetic sensor array, which consists of a 16-channel high-performance magnetoelectric sensor, and the noise equivalent magnetic induction (NEB) of each channel reaches 3-5 pT/Hz1/2@10 Hz. The distribution of the magnetic field is imaged by scanning the magnetic field variation of different positions on the surface. Therefore, the areas of magnetic anomalies are identified by distinguishing different magnetic field abnormal results. and it may be possible to classify the battery failure, so as to put forward suggestions on the use of the battery. This magnetic imaging method expands the application field of this high-performance magnetoelectric sensor and contributes to the battery's safety monitoring. Meanwhile, it may also act as an important role in other nondestructive testing fields.In this study, we proposed a three-dimensional (3D) printed porous (termed as 3DPP) scaffold composed of bioceramic (beta-tricalcium phosphate (β-TCP)) and thermoreversible biopolymer (pluronic F-127 (PF127)) that may provide bone tissue ingrowth and loading support for bone defect treatment. The investigated scaffolds were printed in three different ranges of pore sizes for comparison (3DPP-1 150-200 μm, 3DPP-2 250-300 μm, and 3DPP-3 300-350 μm). SKF-34288 manufacturer The material properties and biocompatibility of the 3DPP scaffolds were characterized using scanning electron microscopy, X-ray diffractometry, contact angle goniometry, compression testing, and cell viability assay. In addition, micro-computed tomography was applied to investigate bone regeneration behavior of the 3DPP scaffolds in the mini-pig model. Analytical results showed that the 3DPP scaffolds exhibited well-defined porosity, excellent microstructural interconnectivity, and acceptable wettability (θ < 90°). Among all groups, the 3DPP-1 possessed a significantly highest compressive force 273 ± 20.8 Kgf (* p < 0.05). In vitro experiment results also revealed good cell viability and cell attachment behavior in all 3DPP scaffolds. Furthermore, the 3DPP-3 scaffold showed a significantly higher percentage of bone formation volume than the 3DPP-1 scaffold at week 8 (* p < 0.05) and week 12 (* p < 0.05). Hence, the 3DPP scaffold composed of β-TCP and F-127 is a promising candidate to promote bone tissue ingrowth into the porous scaffold with decent biocompatibility. This scaffold particularly fabricated with a pore size of around 350 μm (i.e., 3DPP-3 scaffold) can provide proper loading support and promote bone regeneration in bone defects when applied in dental and orthopedic fields.The application of tunnel-slag-improved high liquid limit soil as filling materials in subgrade is a green environmental technology. This study explored the influence of tunnel slag mixing on the physical and mechanical properties of improved soils, based on the engineering background of Liyu highway, Guangxi Province, China. Firstly, the optimal moisture content, maximum dry density, shear strength parameters, California bearing ratio (CBR) and resilience modulus of plain and tunnel-slag-improved high liquid limit soils were experimentally determined. Results showed that the direct utilization of untreated soil was unacceptable in subgrade practice. A significant enhancement of integrity of high liquid limit soils could be obtained by tunnel slag mixing, and the value of 15% was determined as the optimal tunnel slag content in soils, leading to improved soil performance meeting the specification requirements. Then, numerical simulation on the stability of subgrade slope of tunnel-slag-improved soils at the content of 15% was conducted. It also reported the long-term subgrade settlements. The feasibility of utilization of tunnel slag in improving properties of high liquid limit soils was further validated. Finally, a good application of tunnel-slag-improved high liquid limit soil as subgrade filling materials in Liyu highway was achieved. The findings in this study could provide useful guidance for similar engineering.Ti6Al4V (Ti64) alloys manufactured by selective laser melting (SLM) are well known for their susceptibility to failure at a low ductility of less than 10% due to the formation of an (α') martensitic structure. Annealing and solution treatments as post-heat treatments of α' are considered a good way to improve the mechanical performance of SLM-manufactured Ti64 parts. In this research, the effect of heat treatment parameters such as temperature (850 °C and 1020 °C) and cooling rate (furnace and water cooling) on the microstructure and mechanical properties of the SLM Ti64 structure was investigated. It was shown that the tensile strength/ductility of the Ti64 alloy produced by SLM was determined by the post-heat treatment. The experimental results revealed that heat treatment at 850 °C followed by furnace cooling resulted in the best possible combination of ductility (13%) and tensile strength (σy = 932, σu = 986 MPa) with a microstructure consisting mainly of 78.71% α and 21.29% β. Heat treatment at 850 °C fons cooled with water was also studied. It was found that aging influenced the microstructure of the Ti6Al4V parts, including β, α, and α″ precipitation and fragmentation or globularization of elongated α grains. The aging process at 550 °C leads to an increase in tensile strength and a decrease in ductility.The local acidification of secondary anode mortar was regarded as the primary reason for the degradation of the anode system, leading to a decreased service life and uneven distribution of the protection current within the impressed current cathodic protection system for reinforced concrete structures. In related previous studies, a novel type of lightweight functional aggregate was designed and prepared for the secondary anode mortar system, aiming to improve anode performance via acidification mitigation. However, the relationship between optimization effects and this functional component has not been fully clarified. In this study, two sets of experiments were carried out to investigate the effects of lightweight functional aggregates on acidification mitigation and the protection of current distribution. Research results proved that the presence of this functional aggregate was beneficial for mitigated acidification propagation and a more uniform distributed protection current, which demonstrated the importance and effectiveness of acidification inhibition on the optimization of anode performance.An enzymatic route for phosphorous-carbon- bond formation is developed by discovering new promiscuous activity of lipase. This biocatalytic transformation of phosphorous-carbon- bond addition leads to biologically and pharmacologically relevant α-acyloxy phosphonates with methyl group in α-position. A series of target compounds were synthesized with yields ranging from 54% to 83% by enzymatic reaction with Candida cylindracea (CcL) lipase via Markovnikov addition of H-phosphites to vinyl esters. We carefully analyzed the best conditions for the given reaction such as the type of enzyme, temperature, and type of solvent. The developed protocol is applicable to a range of H-phosphites and vinyl esters significantly simplifying the preparation of synthetically challenging α-pivaloyloxy phosphonates. Further, the obtained compounds were validated as new potential antimicrobial drugs with characteristic E. coli bacterial strains and DNA modification recognized by the Fpg protein, N-methyl purine glycosylases as new substrates. The impact of the methyl group located in the α-position of the studied α-acyloxy phosphonates on the antimicrobial activity was demonstrated. The pivotal role of this group on inhibitory activity against selected pathogenic E. coli strains was revealed. The observed results are especially important in the case of the increasing resistance of bacteria to various drugs and antibiotics.Articular cartilage defects, and subsequent degeneration, are prevalent and account for the poor quality of life of most elderly persons; they are also one of the main predisposing factors to osteoarthritis. Articular cartilage is an avascular tissue and, thus, has limited capacity for healing and self-repair. Damage to the articular cartilage by trauma or pathological causes is irreversible. Many approaches to repair cartilage have been attempted with some potential; however, there is no consensus on any ideal therapy. Tissue engineering holds promise as an approach to regenerate damaged cartilage. Since cell adhesion is a critical step in tissue engineering, providing a 3D microenvironment that recapitulates the cartilage tissue is vital to inducing cartilage regeneration. Decellularized materials have emerged as promising scaffolds for tissue engineering, since this procedure produces scaffolds from native tissues that possess structural and chemical natures that are mimetic of the extracellular matrix (ECM) of the native tissue. In this work, we present, for the first time, a study of decellularized scaffolds, produced from avian articular cartilage (extracted from Gallus Gallus domesticus), reseeded with human chondrocytes, and we demonstrate for the first time that human chondrocytes survived, proliferated and interacted with the scaffolds. Morphological studies of the decellularized scaffolds revealed an interconnected, porous architecture, ideal for cell growth. Mechanical characterization showed that the decellularized scaffolds registered stiffness comparable to the native cartilage tissues. Cell growth inhibition and immunocytochemical analyses showed that the decellularized scaffolds are suitable for cartilage regeneration.Good heat dissipation performance of aero-engine an effectively improve the service performance and service life of aero-engine. Therefore, this paper studies the machining method of cooling holes of high-temperature existent material GH 4169 for aero-engine innovatively puts forward the mask electrochemical machining method of cooling holes and explores the entrance morphology and taper formation law of the hole structure of high-temperature resistant material GH 4169. The mathematical model of anode dissolution of cooling holes in ECM is established, and the influence of voltage and electrolyte flow rate on cooling holes in ECM is analyzed. Compared with the mask-less electrochemical machining, the inlet radius of cooling holes in mask electrochemical machining is reduced by about 16.0% and the taper is reduced by 52.8% under the same machining parameters, which indicates that the electrochemical machining efficiency of mask is higher and the machining accuracy is better. Experiments show that the diameter of the mask structure improves the accuracy of the inlet profile of the cooling hole in the ECM.

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