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d stress may be more likely to try to self-medicate with alcohol, and potentially other drugs.This paper documents the collaborative design of a mental health intervention for adolescents in India with anxiety, depression, or anger-related concerns. The process was characterized by three phases of formative activities (1) an intensive review of the service context, (2) selection of an overall design strategy (e.g., whether to choose existing evidence-based treatments or build new treatments in context), and (3) a period of prototyping, testing, and refining. Each phase resulted in specific outputs, which were, respectively, (1) a detailed articulation of values and preferences (setting expectations for what the ideal protocol should be), (2) a set of build parameters representing a blueprint that managed strategic compromises for this context, and (3) a working protocol. We outline the steps of this design process, summarize data from an open-trial clinical case series, and illustrate the resulting working protocol, which will be tested in a future larger trial. We conclude with insights and observations likely to be relevant to protocol design activity in a variety of contexts, most particularly those in low-and-middle-income countries such as India.

Facing an epidemic of childhood obesity and budget constraints, public health administrations are showing an urgent interest in interventions that are both health effective and cost-effective. Thus, this study intends to analyze the return on investment of these existing programs.

All analyses are based on a comprehensive data set from 249 children with obesity and overweight children who participated in the Children's Health InterventionaL Trial (CHILT), an 11-month outpatient multidisciplinary family-based program.

Cost-effectiveness was assessed by comparing estimated savings associated with a reduction in weight and improvement of obesity-related health parameters with intervention costs. Projected future savings in health care expenditures were modeled on existing research, using estimates of health care costs associated with juvenile obesity and remission thresholds of obesity-related disease.

On average, participants achieved a 0.19-unit reduction in the body mass index standard deviation score, showed reduction in their blood pressure values (systolic=-1.76mmHg, diastolic=-2.82mmHg), and showed improvement in their high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol values (HDL=+1.31mg/dL, LDL= -4.82mg/dL). The intervention costs were 1799€ per participant, and the benefits of avoided future health care costs varied by individual. On an aggregated level, future savings amounted to between 1859€ and 1926€ per person, translating into a return on investment of 3.3-7.0%.

This study shows that a multicomponent obesity intervention, such as the CHILT, not only results in weight loss and improves important health parameters but also is cost-effective.

This study shows that a multicomponent obesity intervention, such as the CHILT, not only results in weight loss and improves important health parameters but also is cost-effective.

The purpose of the study was to determine whether listeners were less likely to believe a statement that is produced in an atypical voice, as compared to a typical voice. It was hypothesized that an atypical voice, characterized by abnormal roughness, strain, and pitch, would elicit increased skepticism. This hypothesis was based on previous evidence that there are negative stereotypes against individuals who have a voice disorder, and that increased difficulty processing an utterance can lead to disbelief.

In Experiment 1, 36 listeners rated obscure trivia statements (such as "the elephant is the only mammal that cannot jump" and "the first public library was opened in Vienna in 1745") as definitely false, probably false, probably true, or definitely true. The statements were produced by a speaker who used their typical voice and simulated an atypical voice (of severe deviance according to the CAPE-V), as well as two additional control speakers with typical voices. Experiment 2 was a replication of Experfor job-related success.Nurses play a unique role in responding to the needs of intimate partner violence survivors. However, nurses are not adequately prepared to manage intimate partner violence. This study assessed the effects of intimate partner violence educational interventions on nurses' knowledge, attitudes, and practice. A non-randomized controlled trial was conducted with a convenience sample of nurses (n = 104). Nurses in both the intervention and control groups completed pre- and post-test surveys using the self-reported Physician Readiness to Manage Intimate Partner Violence Survey. An intimate partner violence educational program based on World Health Organization guidelines was administered. The multilevel analysis controlling for pre-test results revealed a significant effect of the intervention on perceived intimate partner violence preparation (p = .000) and knowledge (p = .000), actual knowledge (p = .000), intimate partner violence opinions (attitudes and beliefs) related to preparation (p = .000), legal requirements (p = .00), workplace issues (p = .000), self-efficacy (p = .000), victim understanding (p = .000), victim autonomy (p = .000), and constraints (p = .000). Selleck BiP Inducer X However, the intervention did not affect self-reported practices (p = .583). Intimate partner violence educational programs must be integrated into nursing curricula and in-service training through a system approach.Co-production is a process employed to solve complex issues, recognising the expertise of all stakeholders. This paper reports on co-production undertaken by nursing students, early career nurses and researchers as part of a larger study to design an intervention to increase retention of early career nurses. Mixed methods were used to evaluate the acceptability and feasibility of the co-production process in a UK university. Data were collected prospectively, concurrently and retrospectively via interview and questionnaire, between April 2018 and January 2019. Twelve co-production group members completed the questionnaire and six group members and facilitators were interviewed. Students and early career nurses reported personal benefit from participating; they developed and practised transferrable communication and problem-solving skills, believed they were able to make a difference, enjoyed contributing, found benefit from using the group as a reflective space and considered that co-production produced a credible intervention.

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