Boltonbullock2192

There was no significant correlation between cSCC grading and Ki-67 expression (p > 0.05). Ki-67 antigen tumour marker, widely used to determine the level of tumour cell proliferation. Copyright © 2019 Ibnu T. Alferraly, D. Munir, I. B. Putra, R. J. Sembiring.BACKGROUND Hospital-acquired infection (HAI) is a major problem for the patient's health care and may impact the duration of treatment. Hand hygiene is a simple procedure but giving good prevention usually done among nurses at the hospital. AIM Objective of the study is to determine the effectivity of handwashing method compared to hand rub to eliminate microorganisms on nurse's hands at Sumatera Utara University Hospital. Molidustat order This is an experimental analytic study using random sampling technique. METHODS There were 16 nurses enrolled in this study. There were 2 groups involved; the first group using handwashing with soap and the other one using hand rub. The swabs were taken from each hand from both groups before and after washing their hands. Moreover, the swabs directly sent to Microbiology Laboratory of Sumatera Utara University to identify bacteria which colonise the hand. RESULTS There were no significant differences between using handwashing method compared to hand rub in reducing total bacterial colony on hands (p = 0.088). The average of total colony decreased by using handwashing method is 59.5%, and by using a hand, rub is 47.2%. CONCLUSION Hand hygiene method using alcohol-based hand rub liquid has been recommended by WHO and can replace hand washing method in a particular situation. Copyright © 2019 Tetty Aman Nasution, Rina Yunita, Ayodhia Pitaloka Pasaribu, Fikri M. Ardinata.BACKGROUND Curcumin is a major component in curcuminoid which acts as an anti-inflammatory agent. Curcumin affects several biological markers that are thought to play a role in the pathogenesis of preeclampsia such as IL-10 and COX-2, resulting in an improvement in pregnant women with preeclampsia. AIM To see the effect of perioperative curcumin administration on IL-10 and COX-2 in preeclamptic patients undergoing caesarean section under spinal anaesthesia. METHODS This study was a double-blind, randomised clinical trial conducted at Pirngadi Hospital, USU Hospital and Sundari General Hospital Medan as a hospital network of Faculty of Medicine, North Sumatra University. Group 1 received a drug containing curcumin (as a treatment), and another group received a placebo (as a control). RESULTS There were no significant differences in the median values of COX-2 and IL-10 before and after treatment and also the p-values were greater than 0.05 in both groups (control and treatment). CONCLUSION There is no significant difference between the use of curcumin on serum COX-2 and IL-10 levels. Copyright © 2019 Wulan Fadinie, Aznan Lelo, Dadik Wahyu Wijaya, Sarma Nursani Lumbanraja.AIM To analyse the differential expression of the insulin receptor (IR) gene between moderate continuous and severe continuous training in the T2DM rat model. METHODS This was an experimental study. Healthy male Wistar was used in this study, which divided into sedentary, moderate continuous training, and severe continuous training. Treated groups were assigned to run on the treadmill three times a week for eight weeks consequently. RESULTS The result shown that expression of mRNA IR gene in treated groups decline compared to control. There was a difference mRNA IR gene expression after eight weeks of exercise between MCT and control, SCT and control so are MCT and SCT. IR expression on skeletal muscle in treated groups was different compared with control. The distribution of IR on skeletal muscles in treatment groups was significantly increased compared control, but there was no significant difference distribution between MCT and SCT. HOMA-IR post-test in SCT was lower than MCT but FBG post-test lower in MCT than SCT. CONCLUSION The intensity of exercise makes a difference in IR gene expression between moderate continuous training and severe continuous training after eight weeks of assigned exercise in T2DM rat models. Copyright © 2019 Yetty Machrina, Ambrosius Purba, Dharma Lindarto, Ani Melani Maskoen.Endometriosis is a gynaecological disorder that is often characterised by dysmenorrhea, dyspareunia and or infertility. These symptoms are very common and often found as a symptom of other diseases so that endometriosis is more difficult to diagnose or often diagnosed late. Therefore, diseases like this would be better if we prevent them before they suffer. Although endometriosis is caused by multifactor, we can still do simple prevention and be positive. However, several other factors cause this prevention not to be applied in daily life such as lack of knowledge, inadequate facilities or an environment that does not support. Therefore, health promotion as a medium of information and the establishment of community self-reliance is expected to shift bad habits or form new good habits to be more vigilant and prevent endometriosis. The study was conducted using a quasi-experimental design with the pretest-posttest method and was processed using the Wilcoxon signed-rank test. Based on the results of data analysis, there is a significant increase in the behaviour of female students before and after health promotion. Copyright © 2019 Muhammad Rusda, Dara Hanifa Rahman.BACKGROUND High incidence rate of diabetes mellitus (DM) and increased incidence of complications from DM as well as the use of less effective antidiabetic drugs and high financing to treat demands alternative therapy. AIM This study was conducted to determine the difference in the effect of Arabica coffee gayo bean and leaf extract on blood sugar levels in healthy mice before and after the intervention of extract and fasting and postprandial blood glucose level after consumption of glucose. METHODS This research is an experimental research study. The study used experimental animals which were divided into 8 groups which are the control group (Aquadest), group given Acarbose, the group given the Arabica coffee gayo bean extract with dosage of 50 mg, 100 mg and 200 mg in healthy mice, the group given the Arabica coffee gayo leaf extract with dosage of 30 mg, 60 mg and 120 mg in healthy mice. RESULTS The results of the study obtained are before and after the intervention of extract showed the difference of p= 0.