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25%; P= .001). A multiple regression analysis selected relevant symptoms (hazard ratio [HR], 3.1), familiarity (HR, 1.99), and lockdown period (HR, 2.2) as independent predictors of high-risk lesions (high-risk adenomas and colorectal cancer). No COVID-19 infections were reported among staff and patients.

The overall adherence to CRCS decreased during the pandemic, but the continuation of CRCS colonoscopies was efficacious and safe.

The overall adherence to CRCS decreased during the pandemic, but the continuation of CRCS colonoscopies was efficacious and safe.

We studied the effect of statins on mortality in a nationally representative sample of patients with multiple myeloma, and explored the benefit of statins in a subgroup of patients treated with novel agents.

Patients diagnosed with multiple myeloma between 2007 and 2013 were identified in the SEER-Medicare database using International Classification of Diseases (ICD)-03 codes. ICD-9 and Healthcare Common Procedure Coding System codes were used to identify comorbidities and treatments. We assessed the association of statins with mortality in patients with multiple myeloma using multivariate Cox proportional hazards regression analysis. For subanalysis, we used the same statistical technique to investigate the effect of statins on mortality in myeloma patients treated with novel agents.

A total of 5922 patients were diagnosed with multiple myeloma within the study period. Use of statins was associated with 21% reduction in risk of death (adjusted hazard ratio [aHR] 0.79; 95% confidence interval [CI] 0.74-0.84) among all patients with multiple myeloma. Among the patents treated with novel agents (n= 3603), statins reduced mortality by 10% (aHR= 0.90, 95% CI 0.83-0.98).

Use of statins is likely associated with lower mortality in patients with multiple myeloma.

Use of statins is likely associated with lower mortality in patients with multiple myeloma.

The pursuit of high standards and continuous self-improvement are important aspects of a professional attitude in medicine. However, when identity and self-esteem are dependent on flawless performance, healthy striving can become perfectionism. The present study examines the influence of perfectionism on the learning process of basic instrument handling for minimally invasive surgery (MIS).

Thirty medical students volunteered to participate in the study (19 females, 11 males). The mean age was 19.8 years (SD = 1.8). The Perfectionism Inventory was used to determine the degree of perfectionist characteristics in two main factors Self-evaluative perfectionism and Conscientious perfectionism. Participants practiced with the loops and wire task on a surgical simulator and were tested for skill retention within 48 hours. During practice instrument movement was captured in three-dimensional space using a Leap Motion controller. Performance was assessed by time and total path length travelled by the instruments.

Self-evaluative perfectionism was negatively related to skill retention with regard to movement efficiency, but did not predict change in average time on task. The Conscientious perfectionism factor was not a predictor of skill retention with regard to path length or completion time.

Self-evaluative perfectionism was a significant predictor of change in average pathlength between sessions but did not predict change in average time. The Conscientious perfectionism factor was not a predictor of changes in path length or completion time.

Overly negative self-evaluation during MIS skill practice undermined the learning process. Trainees with self-critical perfectionistic tendencies may not optimally benefit from their efforts during practice.

Overly negative self-evaluation during MIS skill practice undermined the learning process. Trainees with self-critical perfectionistic tendencies may not optimally benefit from their efforts during practice.

General Surgery residents have increasing obligations that limit time with patients. This affects the patient-physician relationship, decreases meaning in work and increases burnout. Patient-Centric Resident Conferences (PCRC)

incorporate patients in resident didactics to promote meaning in work and improve resident confidence in counseling and consenting patients for surgery.

Prospective cohort study of General Surgery residents who participated in standard didactic conferences (control) and modified conferences (PCRC) between 2017 and 2019. Control conferences covered a relevant surgical topic. PCRC had shortened didactics and discussions with patients who had undergone the relevant index operation. Pre- and postconference surveys measured teaching effectiveness, confidence in counseling and consenting, and resident perception of how well the conference supported their decision to pursue surgery. Survey data was compared using chi-squared tests. Qualitative data analysis used ground theory methodologyical career and included patient-centered themes, which can enhance meaning in work. GSK484 datasheet These conferences complement but do not replace standard didactics.

PCRC were associated with stronger motivations for a surgical career and included patient-centered themes, which can enhance meaning in work. These conferences complement but do not replace standard didactics.

Covid-19 spread through blood transfusion has not yet been reported. Despite the prevailing pandemic, there are no recommendations available as yet for testing SARS-CoV-2 antibodies as part of blood screening.

To determine the seroprevalence of SAR-CoV-2 antibodies, its clinical significance and to identify if total antibodies(IgA, IgM, IgG) should be tested or just the specific IgG antibodies only.

Consecutive blood donors donated were screened for standard serological panel of HbsAg, Anti-HCV, Anti-HIV and Syphilis using Cobas-411 analyser and Malaria. All seronegative donors were then screened for COVID serology using the same instrument. These results were compared with the blood donors' seroprevalence checked in a cohort in the first week of June 2020. Pre-COVID-19 period (October 2019) blood donors' archived samples were also compared. Donors who were positive on ECLIA were then tested for specific antibodies (IgM or IgG) by ELISA.

A total of 380 healthy blood donors were included. All were males with the mean age being 30.