Binderupvinther4400

89, 0.95), 0.98 (95% CI 0.89, 1.00) and 0.99 (95% CI 0.98, 0.99), respectively. The RR of joint intervention was 0.64 (95% CI 0.58, 0.73). Hypothetical interventions on psychosocial factors such as social engagement and PWB, as well as fruits and vegetable intake, were beneficial to protect older adults from cognitive impairment.RNA-Seq technology was used to analyze the transcriptome of two rice hybrids, Ajay (based on wild-abortive (WA)-cytoplasm) and Rajalaxmi (based on Kalinga-cytoplasm), and their respective parents at the panicle initiation (PI) and grain filling (GF) stages. Around 293 and 302 million high quality paired-end reads of Ajay and Rajalaxmi, respectively, were generated and aligned against the Nipponbare reference genome. Transcriptome profiling of Ajay revealed 2814 and 4819 differentially expressed genes (DEGs) at the PI and GF stages, respectively, as compared to its parents. In the case of Rajalaxmi, 660 and 5264 DEGs were identified at PI and GF stages, respectively. Functionally relevant DEGs were selected for validation through qRT-PCR, which were found to be co-related with the expression patterns to RNA-seq. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated significant DEGs enriched for energy metabolism pathways, such as photosynthesis, oxidative phosphorylation, and carbon fixation, at the PI stage, while carbohydrate metabolism-related pathways, such as glycolysis and starch and sucrose metabolism, were significantly involved at the GF stage. Many genes involved in energy metabolism exhibited upregulation at the PI stage, whereas the genes involved in carbohydrate biosynthesis had higher expression at the GF stage. The majority of the DEGs were successfully mapped to know yield related rice quantitative trait loci (QTLs). A set of important transcription factors (TFs) was found to be encoded by the identified DEGs. Our results indicated that a complex interplay of several genes in different pathways contributes to higher yield and vigor in rice hybrids.Concern about the increase of cyberbullying underlies this study, which had four objectives (1) to calculate the prevalence of cyberaggressors; (2) to compare non-cyberaggressors with cyberaggressors in other bullying/cyberbullying roles, in psychopathological symptoms, and in self-image of masculinity/femininity, happiness, and empathy; (3) to analyze whether cyberaggressors consulted with a psychologist more than non-cyberaggressors; and (4) to identify predictor variables of cyberaggression. Participants were 1558 Bolivian students aged 13 to 17 years. Seven evaluation instruments were administered, using a descriptive, comparative, cross-sectional methodology. Results (1) 32.7% of cyberaggressors (27.4% occasional, 5.3% severe) were found, with a higher percentage of males; (2) compared to non-cyberaggressors, cyberaggressors engaged in more face-to-face bullying behaviors, suffered more face-to-face victimization and cybervictimization, had more psychopathological symptoms (depression, somatization, obsession-compulsion, interpersonal sensitivity, anxiety, hostility, paranoid ideation, psychoticism), higher overall level of psychopathology, had requested psychological assistance in a greater proportion, self-defined with many attributes associated with masculinity, and felt less happiness and less empathy; and (3) being or having been a cybervictim, being or having been an aggressor of face-to-face bullying, low empathetic joy, and a self-image based on attributes associated with masculinity were predictors of cyberaggression. The need for therapeutic intervention with all those involved and the importance of prevention in the school context are discussed.Background We would like to investigate the prevalence trend, potential risk factors and geographic features of reduced visual acuity (VA) in primary and secondary schoolchildren of Hong Kong. Methods This was a serial cross-sectional study using historical data of schoolchildren aged 6 to 15 years from the annual health checks conducted at Student Health Service Centers across Hong Kong, for the school years of 2000/2001 to 2016/2017. Results The prevalence of reduced VA increased from 49.23% (95% CI, 48.99-49.47) in 2000/2001 to 54.34% (95% CI, 54.10-54.58) in 2011/2012 but decreased to 51.42% (95% CI, 51.17-51.66) in 2016/2017. Girls were less susceptible than boys at age 6-7 (and in grade primary 1-2), but more susceptible at older ages. The prevalence in junior grades increased while the risk effect of grade reduced over the past 17 years. learn more Geographic variation on the risk for reduced VA existed and spatial autocorrelation was positive. The difference in prevalence of reduced VA between Hong Kong and mainland China has decreased in recent years. Cross-border students living in mainland China were associated with a lower risk for reduced VA. Conclusions Further study was proposed to investigate the environmental association between students living in and outside Hong Kong with the prevalence of reduced VA. Multi-level research should also be conducted to investigate the influence of compositional and contextual factors on the prevalence of reduced VA.Although brief alcohol intervention can reduce alcohol use for both men and women, health care providers (HCPs) are less likely to discuss alcohol use or deliver brief intervention to women compared to men. This secondary analysis examined whether previously reported outcomes from a cluster randomized trial of a clinical decision support system (CDSS)-prompting delivery of a brief alcohol intervention (an educational alcohol resource) for patients drinking above cancer guidelines-were moderated by patients' sex. Patients (n = 5702) enrolled in a smoking cessation program at primary care sites across Ontario, Canada, were randomized to either the intervention (CDSS) or control arm (no CDSS). Logistic generalized estimating equations models were fit for the primary and secondary outcome (HCP offer of resource and patient acceptance of resource, respectively). Previously reported results showed no difference between treatment arms in HCP offers of an educational alcohol resource to eligible patients, but there was increased acceptance of the alcohol resource among patients in the intervention arm.