Bergerhensley6077

This pattern was present in patients across a broad range of injury severities. CONCLUSIONS After major trauma, there seems to be an early 'antifibrinolytic gap' with the natural antifibrinolytic system lagging several hours behind the natural profibrinolytics. An early dose of exogenous antifibrinolytic (TXA) might have its effect by filling this gap. The finding that tPA and subsequent clot breakdown (illustrated by D-dimer formation) are raised in a broad range of patients, with little correlation between the initial fibrinolytic response and markers of injury severity, may be the reason that TXA is effective across a broad range of injured patients. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.INTRODUCTION Paediatric injuries are a major cause of mortality and disability worldwide, yet little information exists regarding its epidemiology or prehospital management in low-income and middle-income countries. We aimed to describe the paediatric injuries seen and managed by the prehospital ambulance service, Service d'Aide Medicale d'Urgence (SAMU), in Kigali, Rwanda over more than 3 years. METHODS A retrospective, descriptive analysis was conducted of all injured children managed by SAMU in the prehospital setting between December 2012 and April 2016. RESULTS SAMU responded to a total of 636 injured children, 10% of all patients seen. The incidence of paediatric injury in Kigali, Rwanda was 140 injuries per 100 000 children. 65% were male and the average age 13.5 (±5.3). Most patients were between 15 and 19 years old (56%). The most common causes of injuries were road traffic incidents (RTIs) (447, 72%), falls (70, 11%) and assaults (50, 8%). Most RTIs involved pedestrians (251, 56%), while 15% (65) involved a bicycle. Anatomical injuries included trauma to the head (330, 52%), lower limb (280, 44%) and upper limb (179, 28%). Common interventions included provision of pain medications (445, 70%), intravenous fluids (217, 34%) and stabilisation with cervical collar (190, 30%). CONCLUSION In Kigali, RTIs were the most frequent cause of injuries to children requiring prehospital response with most RTIs involving pedestrians. Rwanda has recently instituted several programmes to reduce the impact of paediatric injuries especially with regard to RTIs. These include changes in traffic laws and increased road safety initiatives. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.Deputy head nurse Katie Whalley applied for and won the first MSD Animal Health Veterinary Nurse Research Bursary, which is supporting her research into improving practice hygiene. British Veterinary Association.BVA Head of Policy and Governance Amelia Findon explains why it's important that members take a moment to submit their vote in the current regional representative elections. British Veterinary Association.Last month, BVA President Daniella Dos Santos travelled to Inverness to find out about the realities of rural and remote veterinary work from members of the Highlands and Islands Veterinary Services Scheme (HIVSS). British Veterinary Association.Fabian Rivers, recent graduate rep on BVA Council, hopes that new graduates will contribute to a BVA initiative that is developing a vision for a good veterinary workplace. British Veterinary Association.According to the 2019 PDSA Animal Wellbeing (PAW) report, 49 per cent of rabbits in the UK still live alone with no companionship. SB-743921 BVA Policy Officer Hayley Atkin explains how you can help get the right message out to pet owners. British Veterinary Association.Professor emeritus of physiology, he led a life of academic excellence, adventure, service, curiosity, integrity and faith. British Veterinary Association.This focus article was prepared by Amanda Carson and colleagues of the APHA Small Ruminant Expert Group. British Veterinary Association.Crufts TV presenter Clare Balding has called for the Kennel Club to get tough on breeders. Adele Waters reports. British Veterinary Association.Legionella longbeachae is the predominant cause of Legionnaires' disease (LD) in New Zealand. Although serogroup 2 (sg2) does not contain the most clinically significant strain, it is an important cause of disease. Here, we report the complete genome sequence of an sg2 isolate from a patient who was hospitalized with LD. Copyright © 2020 Haviernik et al.We isolated phage Ec_Makalu_002, which infects uropathogenic strains of Escherichia coli Here, we report its complete genome sequence, annotated features, and relatedness to other phages.We report the complete genome sequences of 11 virulent Newcastle disease viruses. The isolates were obtained from vaccinated broiler and layer chickens in three different provinces of Indonesia in 2013 and 2014. Phylogenetic analysis revealed that all isolates belong to subgenotype VII.2 in the class II cluster.Here, we report the draft genome sequence of Idiomarina sp. strain W-5T, which was isolated from the Andaman Sea. The genome encodes 2,207 proteins. The Idiomarina sp. strain W-5T whole-genome sequence will help us to understand the metabolic diversity in marine bacteria. Copyright © 2020 Deb and Das.An extremely halophilic archaeon, Salarchaeum sp. strain JOR-1, was isolated from the east coast of the Dead Sea, Kingdom of Jordan, and sequenced using single-molecule real-time (SMRT) sequencing. The GC-rich 2.5-Mbp genome was composed of a circular chromosome and a megaplasmid. The genome contained 2,633 genes and was incorporated into HaloWeb (https//halo.umbc.edu/). Copyright © 2020 Anton et al.BK polyomavirus (BKPyV) is an important pathogen in transplant recipients. We report four draft BKPyV genomes, three of BKPyV genotype I (subtype I-b2) (AUS-105, AUS-106, and AUS-108) and one of genotype II (AUS-107). These draft genomes were identified in longitudinal urine samples collected from a single hematopoietic stem cell transplant recipient. Copyright © 2020 Van et al.Sixty-six Salmonella enterica serovar Typhimurium isolates carrying incompatibility group FIB (IncFIB) plasmids were sequenced to further characterize the IncFIB plasmid-encoded factors associated with virulence and antimicrobial resistance genes. In addition to the IncFIB plasmid, many of these isolates harbored additional plasmids encoding virulence and antimicrobial resistance genes.