Bennedsenlemming0356

(Grade 3b) was detected in the laparoscopy group and managed by ureteroscopy to remove the obstruction under general anesthesia. Significant differences were found in operative time (P = .01) and postoperative hospital stay (P = .01), while medical expenses were similar between the two groups (P = .42). No malignant pathologic findings were observed in biopsied specimens. During follow-up, no recurrence was detected in CT scans. Conclusion In the management of parapelvic cysts, two minimally invasive surgeries were comparable in efficiency. However, fURS was superior to laparoscopic unroofing with regard to the complication rate, operative time, and postoperative hospital stay.Wearable electronics and sensors are increasingly popular for personal health monitoring, including smart shirts containing electrocardiography (ECG) electrodes. Optimal electrode performance requires careful selection of the electrode position. On top of the electrophysiological aspects, practical aspects must be considered due to the dynamic recording environment. We propose a new method to obtain optimal electrode placement by considering multiple dimensions. The electrophysiological aspects were represented by P-, R-, and T-peak of ECG waveform, while the shirt-skin gap, shirt movement, and regional sweat rate represented the practical aspects. This study employed a secondary data set and simulations for the electrophysiological and practical aspects, respectively. Typically, there is no ideal solution that maximizes satisfaction degrees of multiple electrophysiological and practical aspects simultaneously; a compromise is the most appropriate approach. Instead of combining both aspects-which are independent of each other-into a single-objective optimization, we used multi-objective optimization to obtain a Pareto set, which contains predominant solutions. These solutions may facilitate the decision-makers to decide the preferred electrode locations based on application-specific criteria. Our proposed approach may aid manufacturers in making decisions regarding the placement of electrodes within smart shirts.This study is aimed to use shear wave elastography (SWE) to study the relationship between shear modulus and different body postures of the thoracolumbar fascia (TLF) and acquire physiologically meaningful information from the stiffness-posture graph to better quantify passive flexion responses. Seven passive postures were defined to evaluate the shear modulus of right side TLF at the third and fourth lumbar vertebra levels (L3 and L4) in twenty healthy male subjects. L-Glutamic acid monosodium price The TLF stiffness was significantly different among different postures (p less then  0.001), and the TLF stiffness at L3 was always less than that at L4 (p less then  0.001). As the forward tilt increased from 0 to 60°, the TLF stiffness increased in sitting and standing postures by 54.01% and 192.84%. In the neutral postures, the TLF stiffness in standing and sitting postures was 66.98% and 165.48% higher than that in rest posture. The above results show that the elastic properties of TLF play an important role in maintaining body static posture and that the forward tilt and sitting postures are likely to induce low back pain (LBP). In conclusion, this study provides preliminary in vivo data for the relationship between body postures and TLF stiffness.Auditory steady-state response (ASSR) is useful for hearing threshold estimation. The ASSR is usually detected with objective response detectors (ORD). The performance of these detectors depends on the signal-to-noise ratio (SNR) as well as the signal length. Since it is undesirable to increase the signal length, then, this work provides a multivariate technique for improving the SNR and consequently the detection power. We propose the insertion of a short calibration step before the detection protocol, in order to perform a search among the available electroencephalogram (EEG) derivations and select the derivation with the highest SNR. The ORD used in this work was the magnitude-squared coherence (MSC). The standard detection protocol is to use the same EEG derivation in all exams. Using 22-scalp positions, the new technique achieved a detection rate higher than that obtained in 99.13% of the standard detection protocol. When restrictions were applied to the search, a superior performance was achieved. Thus, the technique proposed was able to track the best EEG derivations before exams and seems to be able to deal with the variability between individuals and between sessions.

To report outcomes of stereotactic body radiotherapy (SBRT) in metastatic castration-resistant prostate cancer (mCRPC) patients with oligoprogression (≤ 5 metastases) during first-line treatment with androgen receptor-targeted therapy (ARTT).

Retrospective multi-institutional analysis of mCRPC patients treated with SBRT to oligoprogressive lesions during ARTT. End-points were time to next-line systemic treatment (NEST), radiological progression-free survival (r-PFS) and overall survival (OS). Toxicity was registered according to Common Terminology Criteria for Adverse Events (CTCAE) v4.0. Survival analysis was performed using the Kaplan-Meier method, univariate and multivariate analysis (MVA) were performed.

Data from 34 patients were analyzed. Median NEST-free survival, r-PFS, and OS were 16.97, 13.47, and 38.3months, respectively. At MVA, factors associated with worse NEST-free survival and r-PFS were polymetastatic burden at diagnosis of metastatic hormone-sensitive disease (hazard ratio [HR] 3.66, p = 0.009; HR 3.03, p = 0.034), PSA ≤ 7ng/ml at mCRPC diagnosis (HR 0.23, p = 0.017; HR 0.19, p = 0.006) and PSADT ≤ 3months at mCRPC diagnosis (HR 3.39, p = 0.026; HR 2.79, p = 0.037). Polymetastatic state at mHSPC diagnosis was associated with a decreased OS (HR 4.68, p = 0.029). No patient developed acute or late grade ≥ 2 toxicity.

Our results suggest that SBRT in oligoprogressive mCPRC is safe, effective and seems to prolong the efficacy of the ongoing systemic treatment positively affecting disease progression. Prospective trials are needed.

Our results suggest that SBRT in oligoprogressive mCPRC is safe, effective and seems to prolong the efficacy of the ongoing systemic treatment positively affecting disease progression. Prospective trials are needed.