Batemanharmon6660

Unsupplemented patients with baseline deficiency showed persistently worse glycemic control vs. those with baseline repletion.

Variants in fibroblast growth factor receptor-1 (

) may either cause isolated hypogonadotropic hypogonadism (IHH) or Kallmann syndrome (KS). Although the relationship of genes classically involved in IHH with combined pituitary hormone deficiency (CPHD) is well established, variants in

have been presented as a rare cause of this phenotype recently.

Herein, we report an adopted 16-year-old male presented with delayed puberty and micropenis. He had undergone surgery for bilateral undescended testes in childhood. He was normosmic, and the pituitary imaging was normal. However, hypogonadotropic hypogonadism and growth hormone deficiency were detected, associated with a heterozygous nonsense variant (c.1864 C>T, p.R622X) in

.

variants are among the causes of IHH and KS, which are inherited in an autosomal dominant manner and can be associated with midline defects. It should also be kept in mind that CPHD may be associated with

variants in a subject with normal olfactory function.

FGFR1 variants are among the causes of IHH and KS, which are inherited in an autosomal dominant manner and can be associated with midline defects. It should also be kept in mind that CPHD may be associated with FGFR1 variants in a subject with normal olfactory function.Since antiquity, the Unani system of medicine has been participating in health care system. Usually, four modes of treatment viz. regimenal therapy, dietotherapy, pharmacotherapy and surgery are applied for the treatment of diseases. Regimenal therapy is an important mode in which the morbid matter present in the body is either dispersed/excreted or its unnecessary production is blocked or its flow is restricted and the diseases are cured by natural healer of the body, consequently bring back the humoural stability. Nearly 30 regimens have been mentioned in classical Unani literature. Commonest regimenal procedures such as fasd (venesection/phlebotomy), hijāma (cupping), ta'līq al-'alaq (hirudotherapy/leech therapy), ishāl (purgation), qay' (emesis), idrār-i-bawl (diuresis), huqna (enema), ta'rīq (diaphoresis), riyādat (exercise), dalk (massage), hammām (bathing), tadhīn (oiling), natūl (irrigation), sakūb (douching/spraying), inkibāb (steam/vapour application), takmīd (fomentation) etc. are usually applied for the management of various ailments. These regimenal procedures are completely based on holistic approach and are potential but needs to be explored scientifically. This review outlines the therapeutic applications of various regimens of regimenal therapy used in Unani medicine.Objectives High school has been recognized as a critical period for many students. With the upcoming competition for university admission, they tend to encounter significant stress. Exceeding its optimal level, stress became debilitating and could escalate into school burnout, which entailed various negative outcomes. The current study, hence, was aimed to identify a protective factor that helped mediate the relationship between stress and school burnout in Thai high school students. Self-compassion was selected here, given its relevant conceptual grounds and its cultural relevance (i.e., Thai individuals shown to be particularly oriented toward self-compassion). Methods Data were collected from 170 Thai high school students, who responded to measures of stress, self-compassion, and school burnout. A structural equation model (SEM) was used to test the hypothetical model where the positive association between stress and school burnout was mediated by self-compassion. Results All indices of the model fits were confirmed, and the proposed model explained 80% of the variance in school burnout. Conclusion The role of self-compassion in alleviating the impact of stress on school burnout was shown and relevant implications were discussed.Objectives This study aimed to determine the pattern of aggression among senior secondary school students in Calabar and the psychosocial factors that are associated with it. Methods A descriptive cross-sectional study of 453 randomly selected senior secondary school students utilizing a self-administered Socio-demographic questionnaire obtain data regarding age, gender etc. Procyanidin C1 solubility dmso and a brief interview using the Modified Overt Aggression Scale (MOAS) to determine aggression. Results The mean weighted MOAS score was 26.94 ± 0.02. Males had significantly higher weighted MOAS total score than females (t=6.466, p less then 0.001). There was no gender difference in their aggression against objects but the older adolescents scored higher than the younger ones (t=2.029, p=0.043). Males scored higher in verbal aggression (t=3.064, p=0.002) and physical aggression (t=7.002, p less then 0.001). In the aggression against self-domain, females scored higher than males (t=1.961, p=0.050). All the domains of aggression correlated positively with the total weighted MOAS score, the strongest being with physical aggression (r=0.908, p=0.000). Conclusions Gender appears to play a significant role in aggression among the participants. That females scored higher in aggression to self may have implications for prevention of suicide among youths.Objectives Assessment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection prevalence and immunity is cornerstones in the fight against COVID-19 pandemic. For pandemic control, reliable assays for the detection of anti-SARS-CoV-2 antibodies are required. This pilot external quality assessment (EQA) scheme aimed to independently assess the participants' clinical performance of anti-SARS-CoV-2 testing, to identify shortcomings in clinical practice and to evaluate the suitability of the scheme format. Methods The EQA scheme consisted of eight serum samples with variable reactivity against SARS-CoV-2 intended for the analysis of anti-SARS-CoV-2 immunoglobulin (Ig)G, IgA, and IgM antibodies. Laboratories reported (1) results for each sample and the respective method, (2) raw data from replicate testing of each sample. Results The 16 selected pilot EQA participants reported 294 interpreted results and 796 raw data results from replicate testing. The overall error rate for the anti-SARS-CoV-2 IgG, IgA, and IgM tests was 2.