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Malignant glomus tumors are exceedingly rare, however they can be locally aggressive and have the potential to metastasize. There is limited information available in the literature regarding treatment and outcomes, therefore we present a case series of 5 patients with glomus tumors with malignant features confined to the extremities that have presented to our tertiary sarcoma center within the last 20years. This is the largest case series of its kind in the malignant glomus tumor literature, to our knowledge.

We performed a retrospective chart review of all patients with histologically confirmed glomus tumors with malignant features in the extremities found within the University of Michigan EMERSE database since January 1st, 2000.

Five patients met our inclusion and exclusion criteria. Three patients were diagnosed with malignant glomus tumors, one patient with glomus tumor with uncertain malignant potential, and the last patient with malignant glomus tumor with leiomyosarcomatous features. Males and feenter prior to surgical resection may help reduce the re-resection rate and potential seeding of the tumor in these patients, thereby improving outcomes.

Our study supports the current literature that wide-local resection with the goal of negative margins is still the current gold standard treatment for glomus tumors with malignant features. Studies with larger cohorts are necessary before recommending for or against radiotherapy or chemotherapy. Early biopsy and referral to a tertiary sarcoma center prior to surgical resection may help reduce the re-resection rate and potential seeding of the tumor in these patients, thereby improving outcomes.Complicated pulmonary cysts have a wide range of possible diagnoses with different approaches as they can be benign or malignant. They can resemble malignancies in symptoms and imaging, mainly on positron emission tomography (PET) scan, which can increase the false positivity. We present an infected hydatid cyst resembling a malignancy as it presented with weight loss in a smoker and had necrosis and malignance features on computed tomography and PET scans. MK0752 However, serology tests and fine needle aspiration were suggestive of a hydatid cyst, which made this case quite unique. Other diagnoses should always be suspected even if the malignancy was highly likely due to other lesions can resemble malignancies.Hydatid disease (HD) is an infection with the metacestode stage of the tapeworm Echinococcus. It is commonly seen in South America, The Middle East, Eastern Mediterranean, Africa and China. Hydatid cysts usually affect the liver followed by the lungs. Involvement in other organs has been reported. However, in the majority of the cases, cysts are localized in one organ or one region. We report a rare case of a 36-year-old woman who presented to the hospital in Syria with long-standing history of non-specific abdominal pain. Computerized tomography showed several hydatid cysts in the liver, spleen, left lung, mediastinum (adjacent to the aortic arch), both breasts and above the right gluteal muscles.We report a case of epigastric heteropagus twins with omphalocele. The parasite had two lower limbs, genitalia with developed phallus and scrotum but absent testis and absent anus. An omphalocele was present just below the attachment of the parasitic twin. No kidney or ureter but only a bladder filled with urine seen during exploration. The parasite bowel was attached to an omphalocele sac prolapsing through it and there was connection to the autosite liver, which forms the main source of its blood supply. Surgery was performed in the neonatal period (Day 12 after birth) for both excision of epigastric heteropagus and omphalocele repair.Hyalinizing clear cell carcinoma (HCCC) is a rare, predominantly minor salivary gland tumor. Most of these tumors occur in the oral cavity, mainly the palate and tongue. Primary localization of the tumor in the region of the nasal cavity and paranasal sinuses is extremely rare and, with only a few cases reported in the literature so far. We present an extremely rare case of a 61-year-old woman with hyalinizing clear cell carcinoma (HCCC), occupying the left posterior nasal and nasopharyngeal cavity, as a primary tumor location. The patient total recovery was uneventful, and she is now free of disease at three years postoperative follow-up.Male genital injuries in the form of avulsed laceration of penis and scrotum are less frequent injuries in urological practice. The cases that occur are mostly caused by road traffic accidents, animal attacks, machinery-related accidents and physical/sexual assaults. Here, we report a case of a 28-year-old male with avulsion and traumatic degloving of the penile and scrotal skin with the exposure of the cavernous and spongy penile body, bilateral testes and total amputation of scrotal skin secondary to motor vehicle accident from Nepal. The patient was managed by emergency surgical debridement and reconstruction of the avulsed penile skin and burial of testis in the medial thigh pockets with primary suturing and hemostasis of the amputated scrotal region, which healed with satisfactory esthetic results with normal voiding function and erection of penis.Blunt vascular trauma is rare and challenging in management. Trauma victims who are elderly and have medical comorbidities are still uncommon, but their proportion is expected to increase, as life expectancy has been rising worldwide. A case of blunt vascular trauma to the lower extremity in a 70-year-old patient is reported. During the procedure, a contusion of the superficial femoral artery with thrombosis was identified. Besides, the artery was found to be affected by atherosclerosis. Thrombectomy with resection of the artery and end-to-end anastomosis was performed. Good early clinical outcome was achieved. Nonsystematic review of the available literature is also presented.Epidermoid cysts (ECs) are slow-growing, benign tumors that represent less then 2% of all intracranial tumors. ECs can be divided into following two types extra-axial and intra-axial. Extra-axial ECs are most often positioned in the cerebellopontine angle. Intra-axial ECs, which are also referred to as intraparenchymal ECs, are most commonly found in supratentorial structures, such as the frontal and temporal lobes, accounting for less then 2% of all intracranial ECs and are especially rare in children. In this report, we described a unique case of medulla oblongata EC in a child, to contribute this knowledge to the existing body of literature.