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The pandemic of Coronavirus Disease 2019 (COVID-19), one of the most infectious diseases in the modern history, is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and has had a profound health and economic toll, globally. This paper identifies the overall health status associated with COVID-19 pandemic in all 7 provinces of Nepal, a developing country in South Asia, analyzing data from January 2020 to February 2022. It focuses on the SARS-CoV-2 prevalence, transmission through wastewater and other routes, diagnostics, treatment options, and alternative medicines, thereby offering key perspectives for its management.

Studies regarding coronavirus spanning the 2017 to 2022 period were searched on the web, Nepalese database, and Web of Science. Refined criteria included SARS-CoV-2 in wastewater of Nepal or worldwide. Demographic data (sex, age-group, and geographic location) were also obtained from websites and relevant reports of the Ministry of Health and Population (MOHP) of Nepal, hese findings may guide the researchers and professionals with handling the COVID-19 challenges in developing countries such as Nepal and better prepare for future pandemics.Soybean farming is an important source of income for smallholder farmers in Ghana, particularly in the northern savanna ecological zones, where soil infertility is a challenge. To increase soybean production and farm revenue, farmers must adopt improved soybean production technologies. Smallholder soybean farmers' decisions to embrace high-yielding technology are influenced by various socioeconomic factors. The factors driving the adoption of rhizobium inoculant and mineral fertilizer technologies in Ghana's Tolon district were evaluated using a multinomial logit model with 200 smallholder soybean farmers. According to the findings, the likelihood of using inoculants and inorganic fertilizers increased with herd size, farm size, and access to extension services. In addition, female soybean producers were more likely than their male counterparts to use inoculants and chemical fertilizers. The study also found that soybean producers were less likely to use inoculants and chemical fertilizers because of their distance from the local market. To encourage technology adoption, the study recommends that agricultural extension services to farmers be increased. Farmers should also be encouraged to join farmer-based groups to increase inoculant technology uptake.

The clinical requirements and the indication of the Synacthen test are increasing. The objective of our study is to determine a baseline cortisol level that reliably predicts the response to Synacthen test in a low-risk group of patients.

We performed a cross-sectional analysis of all Synacthen tests conducted between January 2017 and June 2018. The diagnostic accuracy of basal cortisol levels as a predictor of an adequate response to Synacthen test was evaluated by ROC curve analysis.

One hundred and fifty-three patients were included. A baseline cortisol level <40 ng/mL had a sensitivity of 100% but a specificity of 5.8% for the failure of the Synacthen test, while a baseline cortisol level> 147.5 ng/mL showed a specificity of 100% but a sensitivity of 1.2% for an adequate response to the Synacthen test. According to the ROC curve, the optimal baseline cortisol level for predicting an adequate response to the Synacthen test was 85 ng/mL with an AUC of 0.808 (95% CI [0.738-0.877]).

We propose a basal cortisol level assay as a first step in the evaluation of patients with suspected adrenal insufficiency.

We propose a basal cortisol level assay as a first step in the evaluation of patients with suspected adrenal insufficiency.One of the simplest way to characterize the heating efficiency of magnetic fluids used in hyperthermia treatment is the calorimetric measurement of the specific loss power with direct temperature detection. However, the performance of metallic sensors in an alternating magnetic field is degraded by the self-heating of the probes, and electromagnetic interference can be also significant. In our double cell differential thermometric system these disturbing effects can be compensated. Specific loss power measurements of EMG700 magnetic fluid with negative temperature coefficient thermistors in differential configuration are presented, and control measurements were performed with an optical fiber thermometer in f = 470 kHz - 1020 kHz frequency and H = 0.13 kA m - 1 - 1.19 kA m - 1 magnetic field strength range. We found that the specific loss power is proportional to the frequency and shows a quadratic dependence on the field strength in the low field strength region, therefore we calculated the intrinsic loss power of the fluid from the measured specific loss power. At this field conditions intrinsic loss power up to 0.53 nH m 2 kg - 1 was determined.Many countries are suffering from the COVID19 pandemic. The number of confirmed cases, recovered, and deaths are of concern to the countries having a high number of infected patients. Forecasting these parameters is a crucial way to control the spread of the disease and struggle with the pandemic. This study aimed at forecasting the number of cases and deaths in KSA using time-series and well-known statistical forecasting techniques including Exponential Smoothing and Linear Regression. The study is extended to forecast the number of cases in the main countries such that the US, Spain, and Brazil (having a large number of contamination) to validate the proposed models (Drift, SES, Holt, and ETS). The forecast results were validated using four evaluation measures. The results showed that the proposed ETS (resp. Drift) model is efficient to forecast the number of cases (resp. deaths). The comparison study, using the number of cases in KSA, showed that ETS (with RMSE reaching 18.44) outperforms the state-of-the art studies (with RMSE equal to 107.54). The proposed forecasting model can be used as a benchmark to tackle this pandemic in any country.Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained [Cu(l-Thr)(H2O)(phen)]2SO4∙10H2O (1a∙10H 2 O), [Cu(l-Thr)(H2O) (phen)]2SO4∙4.3H2O (1a∙4.3H 2 O), [Cu(μ-l-Thr)(phen)]2SO4∙3.5H2O n (1b∙3.5H 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙2H2O∙CH3OH (1c∙2H 2 O∙CH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙4H2O (1c∙4H 2 O), [Cu(l-Thr)(CH3OH)(phen)]2SO4∙H2O (1d∙H 2 O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)][Cu(SO4)(l-Thr)(phen)]HSO4∙H2O∙3CH3OH (1e·H 2 O·3CH 3 OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(phen)(py)]SO4 (1f) (phen = 1,10-phenanthroline, l-Thr = l-threoninate, py = pyridine). X-ray crystal structure analysis of the prepared ternary coordination compounds revealed extensive hydrogen bonding and π-interactions that link complex species, anions and solvent molecules into 3D architectures. The water/methanol solvent molecules are found in pockets and/or channels in seven solvates. ESR spectra of different types of compounds were also investigated. In all measured compounds the unpaired electron of the copper(II) ion is located in the dx2-y2 orbital which is in agreement with elongated square-pyramidal geometry. Compound 1a∙10H 2 O showed substantial cytotoxic activity toward human hepatocellular carcinoma (HepG2) and acute monocytic leukaemia (THP-1) cell lines.

Due to the ongoing COVID-19 pandemic that began in the winter of 2020, all communities and activities globally have been positively or negatively affected. This scientometric study raises an interesting question concerning whether the volume and characteristics of scientific publishing in all disciplines in 23 Mediterranean countries have been impacted by the pandemic and whether variations in the cumulative totals of COVID-19 cases have resulted in significant changes in this context. The Scopus database and SciVal tool supplied the necessary data for the years targeted for comparison (2019 and 2020), and the annual growth rates and differences were computed. The study used the Mann-Whitney test to examine the significance of the differences between the two years and the Spearman and Kendall correlation tests to evaluate the effect of the number of infections on these differences for all aspects of scientific performance. The findings demonstrated that the COVID-19 pandemic served as a powerful incentive, and the Mediterranean region experienced considerable differences in the volume and features of publications during this crisis. The most substantial implications were the significant growth from 3.1 to 9.4% in productivity and the increases in the annual growth rates of international collaboration, by 12% for the collaboration among Mediterranean countries and 10% for collaboration with the top ten epidemic countries. It was also proven that some characteristics of the publications were positively correlated with the total number of infections. This investigation can help university leaders and decision-makers in higher education and research institutions in these countries make decisions and implement measures to bridge the gaps and motivate researchers in all fields to conduct more research during this ongoing pandemic.

The online version contains supplementary material available at 10.1007/s11192-022-04391-w.

The online version contains supplementary material available at 10.1007/s11192-022-04391-w.

Forcibly Displaced Myanmar Nationals (FDMNs) or Rohingya refugees are one of the vulnerable groups suffering from different kinds of health problems but have been less reported yet. Therefore, the study was designed to delineate the health problems among FDMNs admitted to Cox's Bazar Medical College Hospital.

This hospital-based cross-sectional study was conducted at the Medicine ward, Cox's Bazar Medical College Hospital, for a six-month period following approval. Rohingya refugees who were admitted during the study period were approached for inclusion. Informed written consent was ensured prior to participation. A structured questionnaire was used during data collection. Collected information was recorded in case record form. this website A total of 290 subjects were interviewed. Analysis was performed using the statistical package for social science (SPSS) version 20.

The mean age of the participants was 48.76±18.67 years (range 16-91), with a clear male predominance (60.7%). Family size ranged 6-8. All of the paed between 40 and 60 years.

COPD, CLD and CAP were the most prevalent diseases in FDMN patients who attended the Medicine ward of Cox's Bazar Medical College Hospital. Further exploration is warranted before any policy making and comprehensive plan.

COPD, CLD and CAP were the most prevalent diseases in FDMN patients who attended the Medicine ward of Cox's Bazar Medical College Hospital. Further exploration is warranted before any policy making and comprehensive plan.The estimation of population denominators of internally displaced people (IDP) and other crisis-affected populations is a foundational step that facilitates all humanitarian assistance. However, the humanitarian system remains somewhat tolerant of irregular and inaccurate estimates of population size and composition, particularly of IDPs. In this commentary, we review how humanitarian organizations currently approach the estimation of IDP populations, and how field approaches and analytical methodologies can be improved and integrated.

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