Alsdesai6599

long term following could be collected only in 39.4% of cases. Major Adverse Cardiologic and Cerebral Events (MACCE) occurred in 30.71% controlled patients. Free-MACCE survival was 52.9% at 5. Initially total arterial bypass grafting was superior to other configurations in free-MACCE survival (p=0.036) but we lost significance beyond 5-years following because of selection bias. CONCLUSION Multi arterial coronary artery bypass grafting was secure in early morbidity and mortality. Long term prognosis seemed to be better in case of total arterial revascularization.INTRODUCTION Chronic hepatitis C (CHC) is assimilated to a systemic disease because of its multiple extrahepatic manifestations particularly rheumatological. AIM To determine the prevalence and the characteristics of rheumatological manifestations (RM) associated with CHC. METHODS a retrospective study including all patients suffering from CHC followed over a period of 11 years (2002 - 2012) at the department of gastroenterology B at La Rabta hospital. Were excluded all patients co-infected by hepatitis B virus or by human immunodefficiency virus and those having decompensated cirrhosis. Different RM were collected and analyzed according to the epidemiological, clinico-biological, immunological, virological and histological data of the CHC. RESULTS two hundred and four patients affected by CHC were included, meanly aged by 52 years [22- 66 years]. The sex-ratio was 0,46. RM were noted in 76 patients (37,25%) dominated by inflammatory polyarthralgia of big joints (88,15%). Non erosive arthritis was observed in a woman, myalgia was noted in 11 cases (14,47%) among them, 2 appeared under antiviral treatment. Dryness syndrome was observed in 17 cases (22,36%). RM were associated to other extrahepatic manifestations of CHC in 69,7% of cases, notably to mixed cryoglobulinemia (MC) (60%) and to non specific antinuclear antibodies (21,6%). A partial to total amelioration of RM was noted in most patients under antiviral treatment often associated to symptomatic measures. In univariate analysis, only female sex and presence of MC were significantly correlated to the presence of RM. CONCLUSION RM occur frequently inCHC and are dominated by arthralgia, myalgia and dryness syndrome. Authentic arthritis are uncommon and constitute a diagnostic problem particularly when they inaugurate the disease. MC is the immunological factor the most associated with RM. MR treatment remains mainly antiviral.BACKGROUND Smoking cessation should be a priority for smokers, especially coronary patients. AIM To study the place and effectiveness of acupuncture in smoking cessation in coronary patients. METHODS We conducted a prospective open-label study of 25 coronary smokers treated by acupuncture over a 10-month period, from June 2017 to March 2018. A 2-session protocol acupuncture weekly for three to five weeks, with a positive response. https://www.selleckchem.com/products/epacadostat-incb024360.html In order to evaluate the effectiveness of acupuncture, a questionnaire was completed by the doctor during the treatment, at three and six months after the end of the sessions. Positive response was defined by total cessation of smoking. RESULTS The average age of our patients was 55.5 years (33 to 77 years). The sex ratio of our population was 1.5 with a male predominance. All our patients had a coronary history. The average cigarette consumption was 22.7 pack-years on average. The results of our study showed that acupuncture allows the withdrawal of 5 smokers (20%) from the first session. After the fifth session, 60% of our patients stopped smoking. At the end of the treatment, 17 smokers (70%) stopped smoking completely. At 3 and 6 months of treatment, we observed a stabilization of smoking cessation and decrease rates. CONCLUSION Smoking cessation is difficult to obtain whatever the therapeutic method used, which encourages us to strengthen preventive measures.INTRODUCTION The diagnosis of interstitial lung disease (ILD) requires elimination of underlying connective tissue disease. Consequently, antinuclear antibodies (ANA) are routinely screened in patients with idiopathic interstitial pneumonia. However the clinical usefulness of this practice is not well clear. AIM In this study, we evaluated the frequency of ANA in ILD's patients and investigated the clinical significance of the ANA's presence in these patients. METHODS We conducted a retrospective study of hospitalized patients diagnosed ILD at pulmonary department and for which ANA was performed in the immunology laboratory of our institution. Demographic features, clinical symptoms, biological and radiologic findings and CTD-ILD diagnoses were compared between patients with positive ANA versus negative ANA. RESULTS We enrolled 73 patients. The ANA's prevalence was 32%. There were no significant differences in demographics, pulmonary function test values and radiologic findings between patients with and without ANA. Patients with positive ANA had more cutaneous manifestations (p꞊0.011) and Raynaud's phenomenon (p꞊0.029). The diagnosis of connective tissue disease was made in 42% of patients with positive ANA versus 8% with negative ANA (p꞊ 0.001). ANA's titer higher than 1/320 was predictive of CTD diagnosis (OR꞊14.4) (p less then 0.001). CONCLUSIONS The research of ANA in PID's patients is an important tool of CTD diagnosis specially in those with suggestive symptoms of autoimmune disease.INTRODUCTION Osteoporosis and fractures are known to complicate spondyloarthritis (SA). The Fracture Risk Assessment Tool (FRAX) estimate the 10-year probability of major osteoporotic fracture (MOF) and also hip fracture (FH). It can be useful as risk assessment tools for the purpose of preventing fracture in SA. AIM To measure the bone mineral density (BMD), to evaluate the FRAX and to determinate factors associated with high risk of fracture in patients with SA. METHODS It's a prospective cross-sectional study that included seventy-five patients admitted for SA, in the rheumatology department of Kassab institute in Tunisia. All of them fulfilled the modified New York criteria for SA. RESULTS Sixty-two men and thirteen women were enrolled, with mean age of 36.8 ± 11.8 years. The mean age at disease onset was 27.8± 9.9 years. Mean BASDAI and ASDAS CRP were respectively 3.5 ± 2.4 and 3 ± 0.83. The mean BASRI was 8.9 ± 4.2 and the mean mSASSS was 17.6 ± 19.6. Vitamin D insuffiency and deficiency were found in 43 and 30 patients respectively.