Abildtrupashworth1973

03 to 1) which have severe actuator rate limit. Tyreus-Luyben tuning rule is another optional method. In addition, the reasons why SIMC is not sensitive to rate limit variation are analysed. These analytical results can offer a guideline for practical applications.This paper describes the design and implementation of a H∞-based robust controller for a commercial 2MW variable-speed variable-pitch wind turbine. The single controller is able to deliver specification performance for the entire full load region. Various aspects of modeling and design procedures including reduced order model validation, torsional mode damping of drivetrain and uncertainty estimation are explained in detail. To make the design more reliable and industrially attractive, simple routines for the derivation of required weighting functions are introduced. To investigate the benefits of the suggested design, its closed-loop performance is compared with the wind turbine's baseline controller and an alternative state-space controller proposed in the literature. This is first evaluated using a FAST-based simulator under IEC-61400 compatible scenarios. It is then verified by a real-life hardware in the loop simulator using an industrial PLC.Introduction The purpose of this study was to identify homogenous subgroups of adolescents with emotional and behavioural difficulties using latent profile analysis. The relationship between the latent profile classes and socio-emotional and school adjustment was also analysed. Materials and methods A total of 1,506 students, 667 men (44.3%) were selected by random cluster sampling. The mean age was 16.15 years (SD=1.36). The instruments used were the Strengths and Difficulties Questionnaire, the Personal Wellbeing Index-School Version, The 10-item Positive and Negative Affect Schedule for Children, the Prodromal Questionnaire Brief, the Paykel Suicide Scale, the Cyberbullying-Brief Questionnaire, the Penn Matrix Reasoning Test, and the school performance assessment. Results A total of 7.7% of adolescents obtained risk scores for mental health difficulties. We identified 3 mental health subgroups named Low risk, Externalizing, and Internalizing. These 3 latent classes demonstrated a differential pattern in terms of socio-emotional adjustment and academic performance. Conclusions To identify and validate risk groups of youths for emotional and behavioural problems allows implementing measures to promote emotional well-being and prevent mental health problems. Future studies should continue to analyse young people with emotional and behavioural problems longitudinally and to incorporate new forms of assessment and intervention.Recently implemented photon optimizer (PO) MLC optimization algorithm is mandatory for RapidPlan modeling in Eclipse. This report quantifies and compares the dosimetry and treatment delivery parameters of PO vs its predecessor progressive resolution optimizer (PRO) algorithm for a single-dose of volumetric modulated arc therapy (VMAT) lung stereotactic body radiation therapy (SBRT). Clinical SBRT treatment plans for 12 early-stage non-small-cell lung cancer patients receiving 30 Gy in 1 fraction using PRO-VMAT were re-optimized using the PO-VMAT MLC algorithm with identical planning parameters and objectives. Average planning target volume derived from the 4D CT scans was 13.6 ± 12.0 cc (range 4.3 to 41.1 cc) Patients were treated with 6 MV flattening filter free beam using Acuros-based calculations and 2.5 mm calculation grid-size (CGS). Both treatment plans were normalized to receive same target coverage and identical CGS to isolate effects of MLC positioning optimizers. Original PRO and re-optimized PO plaaverage of 0.2 ± 0.1 minutes (up to 1.0 minutes) with PO 2.5 mm and 1.2 ± 0.39 minutes (maximum up to 3.22 minutes) with PO 1.25 mm plans compared to PRO 2.5 mm plans. PO-VMAT single-dose of VMAT lung SBRT plans showed slightly increased intermediate-dose spillage but boasted overall similar plan quality with less beam modulation and hence shorter beam-on time. However, PO 1.25 mm CGS had less intermediate-dose spillage and analogous plan quality compared to clinical PRO-VMAT plans with no additional cost of plan optimization. selleck chemicals Further investigation into peripheral targets with PO-MLC algorithm is warranted. This study indicates that PO 1.25 mm CGS plans can be used for RapidPlan modeling for a single dose of lung SBRT patients. PO-MLC 1.25 mm algorithm is recommended for future clinical single-dose lung SBRT plan optimization.Background The ultra-high risk (UHR) paradigm allows the investigation of individuals at increased risk of developing psychotic or other mental disorders with the aim of making prevention and early intervention as specific as possible in terms of the individual outcome. Methods Single-session 1H-/31P-Chemical Shift Imaging of thalamus, prefrontal (DLPFC) and anterior midcingulate (aMCC) cortices was applied to 69 UHR patients for psychosis and 61 matched healthy controls. N-acetylaspartate (NAA), glutamate/glutamine complex (Glx), energy (PCr, ATP) and phospholipid metabolites were assessed, analysed by ANOVA (or ANCOVA [with covariates]) and correlated with symptomatology (SCL-90R). Results The thalamus showed decreased NAA, inversely correlated with self-rated aggressiveness, as well as increased PCr, and altered phospholipid breakdown. While the aMCC showed a pattern of NAA decrease and PCr increase, the DLPFC showed PCr increase only in the close-to-psychosis patient subgroup. There were no specific findings in transition patients. Conclusion The results do not support the notion of a specific pre-psychotic neurometabolic pattern, but likely reflect correlates of an "at risk for mental disorders syndrome". This includes disturbed neuronal (mitochondrial) metabolism in the thalamus and aMCC, with emphasis on left-sided structures, and altered PL remodeling across structures.Introduction There is no consensus on how to perform acromioplasty, particularly regarding the level and extent of bone resection, which depend on scapular and humeral morphologies. Hypothesis We aimed to determine whether computer-assisted acromioplasty planning helps surgeons remove impinging bone, reduce unnecessary resections, and improve short-term outcomes of rotator cuff tears (RCR). Patients and methods We randomized 64 patients undergoing RCR of full-thickness supraspinatus tears into two groups 'guided acromioplasty' (GA) and 'freehand acromioplasty' (FA). The pre- and post-operative scapula models were reconstructed using computed-tomography scans to quantify impinging bone removal, unnecessary bone resections, and identify zones of acromial bone removal. All patients were evaluated preoperatively and at 6 months to assess their range of motion (ROM), functional scores and tendon integrity using ultrasound. Results The two groups did not differ in demographics, clinical or morphologic characteristics. Compared to FA, GA tended to lower impinging bone removal (55±26% vs. 43±27%, p=0.087) and to increase unnecessary resection of the total bone removed (49±22% vs. 57±27%, p=0.248). GA resulted in significant anterior under-resection, while FA resulted in significant medial over-resection. Clinical outcomes and ROM improved significantly for all patients, except for internal rotation in the GA group. There were no other significant differences between the two groups, neither in terms of post-operative scores nor in terms of clinical net improvements, nor tendon repair integrity. Conclusions This computer-assisted planning for acromioplasty during RCR proved no benefits in terms of bone removal, tendon healing, or clinical outcomes. link2 Nonetheless such planning tools could help less experienced surgeons improve the efficacy of acromioplasty. Level of proof I, Randomized controlled trial (Therapeutic study).Nursing home residents are at a higher risk of suicidal ideation, and depressive symptoms and limitations on activities of daily living (ADL) are presumed to be contributory factors, whereas resilience may buffer the negative effects of risk factors. link3 This study aimed to investigate the prevalence of suicidal ideation and the moderating effect of resilience on suicidal ideation to dilute the adverse contribution of ADL limitation and depressive symptoms. A stratified random sampling was used to recruit 538 residents from 37 nursing homes in China. Participants' suicidal ideation, resilience, depressive symptoms, and ADL limitation were measured and tested by structural equation modeling. Statistics show that 14.9% of participants had suicidal ideation and the model where resilience moderated the effects of ADL limitation and depressive symptoms on suicidal ideation had the best model fit index. This suggests that positive psychological interventions for resilience building might be effective in reducing suicidal ideation.Purpose To develop a prediction model for postoperative complications after primary one-stage hypospadias correction to improve preoperative parental counseling. Materials and methods In this retrospective cohort study, data were collected from 356 patients with anterior or middle hypospadias who had a one-stage hypospadias correction from 2003 onwards. Potential treatment- and patient-related factors were selected and used to develop a prediction model for postoperative complications within one year (wound-related complications, urinary tract infections, fistulas, stenosis, and prepuce-related complications). Multivariable logistic regression analysis with stepwise backward selection and a p-value of 0.20 was used to select the final model, which was internally validated using the bootstrap procedure. Results Complications within one year postoperatively occurred in 66 patients (19%), of which 13% and 37% were seen in anterior and middle type of hypospadias, respectively. Hypospadias phenotype, surgical technique, chordectomy, and surgeon's experience were included in the final prediction model, whereas none of the patient-related factors were. The final model had a good discriminative ability (bias corrected C statistic 0.70) and calibration. Conclusion Using easily obtainable information, this model showed good accuracy in predicting complications within one year after hypospadias surgery. It is a first step towards individualized risk prediction of postoperative complications for anterior and middle hypospadias and can assist in preoperative parental counseling. Type of study Prognostic study. Level of evidence Level II.Purposes The descending thoracic aorta typically crosses posterior to the left mainstem bronchus (LMSB). We sought to evaluate patient factors that may lead one to consider a posterolateral descending thoracic aortopexy (PLDA) in addition to a posterior tracheopexy (PT) in the surgical treatment of symptomatic tracheobronchomalacia (TBM) that involves the LMSB. Methods Retrospective review of patients who underwent PT with or without PLDA between 2012 and 2017. Severity and extent of TBM were assessed using dynamic tracheobronchoscopy. Aortic positioning compared to the anterior border of the spine (ABS) at the level of the left mainstem bronchus was identified on computed tomography (CT). Factors associated with performing a PLDA were evaluated with logistic regression. Results Of 188 patients who underwent a PT, 70 (37%) also had a PLDA performed. On multivariate analysis, >50% LMSB compression on bronchoscopy (OR 8.06, p 50% anterior to the ABS. Level of evidence III TYPE OF STUDY Retrospective comparative study.