Aagaardfox0587

15, 0.22 ]), exclusion of participants from analyses (differences in ES 0.13 [95% CI -0.03, 0.29]), lack of good control of incomplete outcome data (differences in ES 0.14 [95%CI -0.02, 0.30]) and analysis by "as treated"(differences in ES-0.39 [95%CI -0.99, 0.2]) or "per protocol" (differences in ES-0.46 [95%CI -0.92, 0]) analyses were more likely to have higher effects than those that did not.

These findings suggest that attrition, missing data, compliance, and related biases have an influence in treatment effect estimates in rehabilitation trials. Therefore, these results should be taken into consideration when designing, conducting and reporting trials in the rehabilitation field.

These findings suggest that attrition, missing data, compliance, and related biases have an influence in treatment effect estimates in rehabilitation trials. Therefore, these results should be taken into consideration when designing, conducting and reporting trials in the rehabilitation field.

Attrition, missing data, compliance, and related biases can influence the magnitude of treatment effects in randomized controlled trials (RCTs). It is unclear which items should be considered when reporting and evaluating the influence of these biases in trial reports in the rehabilitation field. The aim was to describe which individual items considering attrition, missing data, compliance, and related biases are included in quality tools used in rehabilitation research. In addition, we aimed to determine whether the existing reporting guidelines, such as the CONSORT and its extensions include all relevant items related to these biases when reporting RCTs in the area of rehabilitation.

Comprehensive literature searches and a systematic approach to identify tools and items looking at attrition, missing data, compliance and related biases in rehabilitation were performed. We extracted individual items linked to these biases from all quality tools. We calculated the frequency of quality items used across too the field of rehabilitation to facilitate the reporting as well as the conduct of RCTs.

Although many items have been described by existing tools and the CONSORT statement (and its extensions) that deal with attrition, missing data, compliance, and related biases, several gaps in reporting were identified. It is crucial that future research investigate a core set of items to be used in the field of rehabilitation to facilitate the reporting as well as the conduct of RCTs.

Trunk training after stroke is an effective method for improving trunk control, standing balance and mobility. The SWEAT² study attempts to discover the underlying mechanisms leading to the observed mobility carry-over effects after trunk training.

A secondary analysis investigating the effect of trunk training on muscle activation patterns, muscle synergies and motor unit recruitment of trunk and lower limbs muscles, aimed to provide new insights in gait recovery after stroke.

Randomized controlled trial.

Monocentric study performed in the rehabilitation hospital RevArte (Antwerp, Belgium) POPULATION Forty-five adults diagnosed with first stroke within five months, of which 39 completed treatment and were included in the analysis.

Participants received 16 hours of additional trunk training (n=19) or cognitive training (n=20) over the course of four weeks (1 hour, 4 times a week). They were assessed by an instrumented gait analysis with electromyography of trunk and lower limb muscles. Outcome measue control and endurance of trunk musculature after sub-acute stroke.

Severe infectious complications are a frequent problem in patients with disability due to a severe acquired brain injury. Previous studies reported that the rehabilitation outcome is significantly lower in patients colonized or infected. However, these results could be influenced by comorbidities of those patients admitted in rehabilitation hospital with a lower functional status.

To explore the influence of systemic infection, in particular concerning multidrug resistant bacteria and analyze the role of comorbidities, as a risk factor for the development of systemic infection, on rehabilitation outcomes in patients with severe brain injury.

This research is a cohort, prospective-observational study, comparing patients with and without systemic infections, in terms of rehabilitation outcomes.

An Italian Intensive Care Rehabilitation Department.

A group of 221 patients (mean age 59 years, range 16-93 years, 127 males, 94 females) with severe acquired brain injury admitted to rehabilitation hospital.

g lower functional status at admission. In the secondary analysis, worst outcome was found in patients with positive blood culture in terms of FIM (P=0.033), GOS (P=0.048), and CRS-R (P=0.001).

Systemic infections during rehabilitation increased the length of hospitalization and reduce the rehabilitative outcomes, even when the analysis was performed on groups matched for the functional status at admission. Moreover, the cardiological and endocrine metabolic comorbidities seem to influence the outcome, without representing a further risk factor for systemic infection.

The impact of infections during rehabilitation inpatient should be more taken into account, with specific procedures and suitable environments to avoid the diffusions of infections.

The impact of infections during rehabilitation inpatient should be more taken into account, with specific procedures and suitable environments to avoid the diffusions of infections.

The Coronavirus disease 2019 (COVID-19) pandemic, caused by symptomatic severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) infection, has wreaked havoc globally, challenging the healthcare, economical, technological and social status quo of developing but also developed countries. For instance, the COVID-19 scare has reduced timely hospital admissions for ST-elevation myocardial infarction in Europe and the USA, causing unnecessary deaths and disabilities. While the emergency is still ongoing, enough efforts have been put to study and tackle this condition such that a comprehensive perspective and synthesis on the potential role of breakthrough healthcare technologies is possible. Indeed, current state-of-the-art information technologies can provide a unique opportunity to adapt and adjust to the current healthcare needs associated with COVID-19, either directly or indirectly, and in particular those of cardiovascular patients and practitioners.

We searched several biomedical databases, websites future, for COVID-19 as well as other diseases.

We are confident that refinement and command of smartcare technologies will prove extremely beneficial in the short-term, but also dramatically reshape cardiovascular practice and healthcare delivery in the long-term future, for COVID-19 as well as other diseases.

Non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis with inflammation, ballooned hepatocytes, and possible fibrosis, which may progress to liver cirrhosis. Although liver biopsy, remains the diagnostic gold standard of NASH, several noninvasive biomarkers have been studied, to avoid the need for this invasive procedure. We performed a systematic review with meta-analysis to evaluate the accuracy of several noninvasive biomarkers in predicting NASH and assessing liver fibrosis in NASH patients.

An electronic search on PubMed and EMBASE was systematically performed. The principal summary outcome was the area under the curve (AUC), assessing the accuracy of NashTest, BARD (body mass index, AST/ALT ratio, diabetes) score, NAFLD fibrosis score (NFS), APRI (aspartate aminotransferase-to-platelet ratio index), and fibrosis-4 (FIB-4) index in predicting NASH and assessing liver fibrosis.

Thirteen studies involving 6,557 adult patients were included in the qualitative assessment of this review, out of which, six studies were included in the quantitative assessment. Prediction of NASH was evaluated better using NFS (AUC of 0.687) and FIB-4 (AUC of 0.729). Fibrosis stages 0 vs. 1-4 was diagnosed better using NFS (AUC of 0.718) and FIB-4 (AUC of 0.723). Advanced fibrosis was assessed better by BARD (AUC of 0.673), APRI (AUC of 0.762), NFS (AUC of 0.787) and FIB-4 (AUC of 0.821).

FIB-4 predicted NASH and quantified liver fibrosis, stages 0 vs. 1-4 more precisely compared to NFS, APRI, and BARD. However, considering that methodological quality of the assessed studies is limited, the results should be considered with caution.

FIB-4 predicted NASH and quantified liver fibrosis, stages 0 vs. 1-4 more precisely compared to NFS, APRI, and BARD. IPA-3 cell line However, considering that methodological quality of the assessed studies is limited, the results should be considered with caution.

To discuss the mechanism of injury and characterize the clinical features of ocular trauma associated with elastic cord exercise equipment band injuries in a consecutive series of patients seen at a single vitreoretinal surgery practice.

We performed a retrospective review of all patients who were treated for blunt trauma from 2013 to 2020 at a single vitreoretinal practice.

Thirteen eyes from 11 patients met the inclusion criteria of possessing ocular trauma secondary to recoil from exercise bands. Presenting visual acuity ranged from 20/16 to HM (median 20/32). The most frequently observed anterior segment pathologies were traumatic iritis (54%) and angle recession (31%). The most common posterior segment findings were vitreous hemorrhage (54%) and peripheral commotio retinae (54%). Three eyes (23%) required surgical intervention. Follow up intervals ranged from 0 to 10 months (median 1.75 months). Visual acuity at last examination ranged from 20/13 to 20/400 (median 20/40).

A wide spectrum of serious ocular injuries requiring medical and surgical intervention can result from this form of blunt ocular trauma. The frequency of this event would be decreased by the use of sports goggles and careful inspection of equipment for wear and over use.

A wide spectrum of serious ocular injuries requiring medical and surgical intervention can result from this form of blunt ocular trauma. The frequency of this event would be decreased by the use of sports goggles and careful inspection of equipment for wear and over use.

To describe the occurrence of full thickness macular hole (FTMH) formation and spontaneous closure in a case of central retinal vein occlusion (CRVO) treated with intravitreal Ranibizumab (RBZ).

A 67 year old hypertensive male presented with acute CRVO with macular edema in his left eye for which he received intravitreal RBZ. He developed a FTMH following the second injection, which was kept under observation. Recurrence of intraretinal edema allowed approximation of the MH edges which subsequently achieved closure with further intravitreal RBZ and formation of an epiretinal membrane.

FTMH formation in acute CRVO after intravitreal RBZ though rare, can occur in eyes with massive macular edema and absence of posterior vitreous detachment following intravitreal pharmacotherapy. Spontaneous closure of secondary holes can take place with improvement in visual acuity.

FTMH formation in acute CRVO after intravitreal RBZ though rare, can occur in eyes with massive macular edema and absence of posterior vitreous detachment following intravitreal pharmacotherapy.