Rittermosegaard9908

l excision followed by proton beam radiotherapy. This treatment approach may enable maximum tumour control. This protocol has not been adequately described in the world literature for this diagnosis.Background and Objectives Uterine sarcomas represents only 3% of all the female genital tract ones. The tumoral stage is the most significant prognostic factor. The role of the bilateral salpingo-oophorectomy (BSO) in the surgical management of FIGO stage IA and IB appears still controversial. This review aims to investigate the impact of bilateral adnexectomy in the treatment of uterine sarcoma. Methods Following the recommendations in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, we systematically searched the PubMed, Scopus, Cochrane, Medline, and Medscape databases in February 2022. We applied no language or geographical restrictions, but we considered only English studies. We included the studies containing data about Recurrence Rate (RR), Disease-free Survival (DFS), and Overall Survival (OS). We used comparative studies for meta-analysis. Results Seventeen studies fulfilled the inclusion criteria; 2 retrospective observational studies, and 15 retrospective comparative studies, And 14 out of the 15 comparative studies were enrolled in meta-analysis. A total of 3743 patients were analyzed concerning the use of adnexectomy with hysterectomy in patients with uterine sarcoma and compared with those who did not. Meta-analysis highlighted a non-significant worsening of the OS in the BSO group compared to the OP group and showed that adnexectomy does not improve the DFS (BSO OR 1.23 (95% CI 0.81-1.85) p = 0.34; I2 = 24% p = 0.22). Conclusions Most studies selected for our review showed that adnexectomy does not significantly affect the RR, OS, and PFS in treating FIGO stage I uterine sarcomas. Therefore, even if there is a unanimous consensus about bilateral adnexectomy in menopausal patients, preservation of ovarian tissue may be considered in premenopausal women. Nonetheless, there are not enough cases in the literature to recommend this procedure.Background and objectives Myocardial perfusion imaging with cardiac single-photon emission tomography (SPECT) is widely available for the detection of coronary artery disease (CAD) with high diagnostic and prognostic accuracy for women. Lorlatinib solubility dmso A large proportion of symptomatic women with true myocardial perfusion defects in SPECT referred to coronary angiography have an absence of CAD-a condition named INOCA (ischemia with nonobstructive CAD). Additionally, the INOCA endotypes are rarely correctly diagnosed, and therefore, no tailored therapy is prescribed. Materials and methods The cardiac SPECT for women was performed from 2018 to 2021. Patients with perfusion defect were analyzed according to further prescribed diagnostic tests used to diagnose CAD. According to the diagnostic criteria, patients with INOCA were selected as candidates for invasive microvascular physiology measurements. The correlation was calculated between SPECT results and clinical characteristics, symptoms, and risk factors. Results A total of factors and varying clinical presentation. The study will be continued by performing invasive testing of coronary microvascular function to expand the competence about what is known about INOCA patients.The grain boundary (GB) plays a crucial role in dominating hydrogen-induced plastic deformation and intergranular failure in polycrystal metals. In the present study, molecular dynamics simulations were employed to study the effects of hydrogen segregation on dislocation plasticity of a series of symmetrical tilt grain boundaries (STGBs) with various hydrogen concentrations. Our study shows that hydrogen both enhances and reduces dislocation nucleation events from STGBs, depending on different GB structures. Specifically, for ⟨001⟩ STGBs, hydrogen does not affect the mode of heterogeneous dislocation nucleation (HDN), but facilitates nucleation events as a consequence of hydrogen disordering the GB structure. Conversely, hydrogen retards dislocation nucleation due to the fact that hydrogen segregation disrupts the transformation of boundary structure such as Σ9 (2 2 1¯) ⟨11¯0⟩ STGB. These results are helpful for deepening our understanding of GB-mediated hydrogen embrittlement (HE) mechanisms.Low-carbon steel pipelines are frequently used as transport pipelines for various media. As the pipeline transport industry continues to develop in extreme directions, such as high efficiency, long life, and large pipe diameters, the issue of pipeline reliability is becoming increasingly prominent. This study selected Q235 steel, a typical material for low-carbon steel pipelines, as the research object. In accordance with the pipeline service environment and the accelerated corrosion environment test spectrum, cyclic salt spray accelerated corrosion tests that simulated the effects of the marine atmosphere were designed and implemented. Corrosion properties, such as corrosion weight loss, morphology, and product composition of samples with different cycles, were characterized through appearance inspection, scanning electron microscopy analysis, and energy spectrum analysis. The corrosion behavior and mechanism of Q235 low-carbon steel in the enhanced corrosion environment were studied, and the corrosion weight loss kinetics of Q235 steel was verified to conform to the power function law. During the corrosion process, the passivation film on the surface of the low-carbon steel and the dense and stable α-FeOOH layer formed after the passivation film was peeled off played a role in corrosion resistance. The passivation effect, service life, and service limit of Q235 steel were studied and determined, and an evaluation model for quick evaluation of the corrosion life of Q235 low-carbon steel was established. This work provides technical support to improve the life and reliability of low-carbon steel pipelines. It also offers a theoretical basis for further research on the similitude and relevance of cyclic salt spray accelerated corrosion testing.MIL-100(Fe) is a metal-organic framework (MOF) characterized by the presence of Lewis acid and Fe(II/III) redox sites. In this work, different synthesis methods for the preparation of MIL-100(Fe) are studied. Depending on the source of fluorine, different phases can be obtained MIL-100(Fe) and an Fe trimesate with unknown structure which we call Fe(BTC). These materials were characterized using numerous techniques and applied in the reaction of CO2 cycloaddition with epichlorohydrin, a reaction catalyzed by Lewis acid sites. It was observed that samples with more Fe(BTC) phase were more active in the reaction. However, all samples, under reaction conditions, transformed into a less active phase.For the first time, the possibility of obtaining B-site disordered, Ruddlesden-Popper type, high-entropy oxides has been proven, using as an example the LnSr(Co,Fe,Ga,Mn,Ni)O4 series (Ln = La, Pr, Nd, Sm, or Gd). The materials were synthesized using the Pechini method, followed by sintering at a temperature of 1200 °C. The XRD analysis indicated the single-phase, I4/mmm structure of the Pr-, Nd-, and Sm-based materials, with a minor content of secondary phase precipitates in La- and Gd-based materials. The SEM + EDX analysis confirms the homogeneity of the studied samples. Based on the oxygen non-stoichiometry measurements, the general formula of LnSr(Co,Fe,Ga,Mn,Ni)O4+δ, is established, with the content of oxygen interstitials being surprisingly similar across the series. The temperature dependence of the total conductivity is similar for all materials, with the highest conductivity value of 4.28 S/cm being reported for the Sm-based composition. The thermal expansion coefficient is, again, almost identical across the series, with the values varying between 14.6 and 15.2 × 10-6 K-1. The temperature stability of the selected materials is verified using the in situ high-temperature XRD. The results indicate a smaller impact of the lanthanide cation type on the properties than has typically been reported for conventional Ruddlesden-Popper type oxides, which may result from the high-entropy arrangement of the B-site cations.Laser shock peening (LSP) has been employed to improve the mechanical properties of repaired aerospace engine components via laser metal deposition (LMD). This study looked at cross-sectional residual stress, microstructure and high cyclic fatigue performance. The outcomes demonstrated that a compressive residual stress layer with a value of 240 MPa was formed at a depth of 200 μm in the laser melting deposited zone and the microhardness was improved by 13.1%. The findings of electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM) analysis revealed that misorientation increased and dislocation features were observed after LSP which is beneficial to the enhancement of fatigue performance. The high cycle fatigue data illustrated that the LMD+LSPned samples exhibited 61% improvement in comparison to the as-LMD samples. In the aerospace sector, LSP and LMD are therefore very effective and promising techniques for restoring high-value components.Material as well as process variations in the composites industry are reasons to develop methods for in-line monitoring, which would increase reproducibility of the manufacturing process and the final composite products. Fiber Bragg Gratings (FBGs) have shown to be useful for monitoring liquid-composite molding processes, e.g., in terms of online gel point detection. Existing works however, focus on in-plane strain measurements while out-of-plane residual strain prevails. In order to measure out-of-plane strain, FBG inscribed in highly birefringent fiber (HB FBG) can be used. The purpose of this research is the cure stage detection with (a) FBG inscribed in single mode and (b) FBG inscribed in highly-birefringent side-hole fiber in comparison to the reference gel point detected with an in-mold DC sensor. Results reveal that the curing process is better traceable with HB FBG than with regular FBG. Thus, the use of HB FBG can be a good method for the gel point estimation in the RTM process.The properties of duplex steels can be seriously affected when welding processes are performed on them. Duplex S32001 is a recent development, so there is very little published information on its behavior after a welding process. For this reason, the present article determines how the main welding parameters of the GMAW process influence its mechanical and microstructural properties. From this study, it was determined that the parameter W/m3 best defines the phase balance in the bead due to the values involved. In the HAZ, this parameter is the t12/8. The welding parameters that are used determine the bead dimensions and geometry. These dimensions induce differences in the distribution of heat in the material. For this reason, the thermal cycles undergone by the material vary and, consequently, in the phase balance obtained. A theoretical study of the chemical composition in the bead, through dilution, and in the HAZ, through diffusion, was carried out. A mathematical model was developed that allows the variation of the composition in the HAZ that induces diffusion to be determined.