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5% vs. 20.9%; P=0.067, and 22.9% vs. 5.0%; P=0.026, respectively). The number of individuals with a left-axis deviation and a left anterior fascicular block was significantly higher in the patients suffering from AS than in the control group. The number of patients with aortic valve involvement was comparable between the groups (P=0.332). Conclusion The most common cardiac involvement in our patients with AS was left ventricular dysfunction, followed by rhythm disturbances and aortic valve insufficiency. These findings were independent of age, AS severity, and disease duration. Therefore, the implementation of cardiovascular screening can be recommended for patients with AS.The outbreak of SARS-CoV-2 (COVID-19) has attracted much attention to study its possible presence and airborne transmission. The possibility of COVID-19 airborne transmission in indoor environments is debatable. The present study examined the concentration of viral RNA-containing particles produced directly or indirectly by breathing or coughing of confirmed COVID-19 patients or by carriers without symptoms. Some studies do not accept this method of transmission (COVID-19 airborne transmission). The present study aimed to measure the possible exposure of health care personnel to SARS-CoV-2 particles that may have been suspended in the air to respond to the hypothesis of COVID-19 airborne transmission. Airborne particle sampling was performed using impingement method based on NIOSH (chapter BA) and ASHRAE. Selection of sampling sections was in line with the WHO guidelines. The samples were analyzed using RT-PCR technique. Based on the given results, airborne particles of COVID-19 may present in the air and affect the health of hospital personnel. In fact, the analysis of gene expression in ambient conditions and thereby aerosol transmission of SARS-CoV-2 through air is possible and may lead to occupational exposure of health care personnel. Furthermore, it was found that airborne emission of COVID-19 through the breathing zone of patients, particularly in ICU wards with confirmed cases of COVID-19, may be higher than in other ICU wards. Also, the demonstrated results showed that there is a possibility of reaerosolization (reintroduction) of previously airborne SARS-CoV-2 particles into the atmosphere due to health care personnel frequently walking between different wards and stations of ICU.Coronavirus disease 2019 (COVID-19) is spreading all over the world in a short time. It originated from Wuhan City of China in the late 2019. Proper vaccines have still been in progress; the spread of the virus is contracted by lockdown and social distancing protocols. These lockdowns resulted in significant benefits, improving the quality of air and reducing the level of environmental pollution. In this context, the study proposes to identify the air quality in the region and its relation with COVID-19-affected people in metropolitan cities of India during COVID-19 lockdowns using a geographical information system (GIS), where over 90% of commercial and industrial sites and 100% school and colleges were closed. The study outcomes highlight the areas encountering high levels of pollution under the pre-lockdown scenario and have seen a higher number of cases. The relation is most evident for PM2.5, which is responsible for respiratory disorders and is the place of attack of SARS-CoV-2. This approach provides comparable outcomes with other decision-making tools. Our primary precedence should be to develop communities to enable people to remain healthy and stay. Healthy societies are crucial not only for people's health, but also for sustainable development. Centered on GIS is concealed; moreover, it is very flexible to use by policymakers.

Over the last two decades transcatheter aortic valve replacement (TAVR) has been approved for clinical use. The anaesthetic choice for this procedure is evolving. General anaesthesia was the predominant anaesthetic technique. Growing experience and advances in technology and economic considerations have led to an increasing interest in performing TAVR under monitored sedation.

The assessment of monitored sedation, called cooperative sedation, involves pharmacologically mediated suppression of consciousness and preservation of verbal contact in response to stimulation as a safe method of anaesthesia for TAVR.

Sixty out of 63 TAVR patients with femoral access received monitored sedation. VPS34 inhibitor 1 concentration Dexmedetomidine was administered in most of such cases (46 patients). A questionnaire was also carried out by staff involved in performing TAVR procedures, with more than 5 years of experience in it, concerning the method of anaesthesia and perioperative care.

Conversion to general anaesthesia was required in 10% of patients (6 cases), only one as a patient-related complication (hypercarbia). The questionnaire carried out showed that anaesthesia and postoperative care after TAVR are underestimated.

The preliminary results regarding anaesthetic management in TAVR procedures demonstrate that monitored sedation is safe, provided that contraindications are observed.

The preliminary results regarding anaesthetic management in TAVR procedures demonstrate that monitored sedation is safe, provided that contraindications are observed.

Constrictive pericarditis (CP) usually presents as a result of chronic fibrous pericardial thickening and calcification of the pericardium which causes reduced cardiac output. Despite the lack of prospective studies comparing the different therapeutic strategies, surgical pericardiectomy is a valuable treatment under most circumstances.

We analyzed our records to highlight the predictors of morbidity and mortality of pericardiectomy and also short-term surgical outcome of the same procedure in a single center.

We carried out a comprehensive retrospective analysis of the records of patients who underwent surgery for CP at our institute between 2013 and 2018. 30 patients underwent isolated pericardiectomy. All patients underwent median sternotomy and total pericardiectomy without the use of cardiopulmonary bypass. Pre-operative, intra-operative and post-operative characteristics were noted.

Fifteen patients had a history of pulmonary tuberculosis. link2 The majority of the patients presented with NYHA grade III or IV. 60% of the patients were male. The preoperative mean central venous pressure was 24 ±9 mm Hg and decreased to 9 ±5 mm Hg after surgery. The 30-day mortality was 6.66% (2/30). Morbidity was mainly due to low-cardiac output syndrome (

= 4). A total of 26 patients had significant improvement in their NYHA status.

Although pericardiectomy for CP remains associated with some operative mortality, the short-term outcome is favorable, and surgical treatment is able to improve the functional class in the majority of survivors.

Although pericardiectomy for CP remains associated with some operative mortality, the short-term outcome is favorable, and surgical treatment is able to improve the functional class in the majority of survivors.

Veno-venous extracorporeal membrane oxygenation (ECMO) support has been used for respiratory insufficiency. Its role in blood oxygenation has been well documented. However, the effects on myocardial electrophysiology have not been studied in detail.

To reveal the acute effects of extracorporeal support on new electrocardiography (ECG) parameters in patients with preserved left ventricular functions.

This retrospective study was conducted in three separate clinics. Sixteen consecutive patients under veno-venous ECMO for respiratory insufficiency who soon could be successfully weaned were analyzed. Immediately before and 2 hours after initiation of ECMO, ECG was performed. P wave, QT, QTc and T wave peak to end were measured and calculated from obtained surface 12-lead ECG.

There were statistically significant differences immediately before and 2 hours after initiation of ECMO treatment in the Tp-e interval and Tp-e/QTc ratio, the maximum QTc, minimum QTc, and QTc dispersion values, and P wave dispersion (

< 0.0001 for each). All ECG parameters were significantly decreased with ECMO support.

All atrial and ventricular repolarization parameters were decreased in patients with VV-ECMO support. Despite the limited role of ECMO in intractable arrhythmias, the findings of the study revealed that ECMO therapy for respiratory insufficiency may improve atrial ventricular depolarization and repolarization. Therefore, simple 12-lead surface ECG with new ECG parameters may be evaluated for better outcomes.

All atrial and ventricular repolarization parameters were decreased in patients with VV-ECMO support. Despite the limited role of ECMO in intractable arrhythmias, the findings of the study revealed that ECMO therapy for respiratory insufficiency may improve atrial ventricular depolarization and repolarization. Therefore, simple 12-lead surface ECG with new ECG parameters may be evaluated for better outcomes.

It is unclear whether it is possible to determine the training load on the basis of the 6-minute walk test (6-MWT) in patients after cardiac surgery with low tolerance of physical exercise.

Use of the 6-MWT to determine an individual initial training load in walking training on a treadmill in the early phase of cardiac rehabilitation in men after coronary artery bypass graft (CABG) surgery.

Twenty-two men aged 54 to 74 years, up to 3 months after CABG surgery participated in walking training on a treadmill (12-15 sessions). link3 Patients underwent the initial and final treadmill exercise stress test (TEST) and the 6-MWT. Based on 6-MWT results, the initial training load was prescribed. Before the 6-MWT and 3 minutes after its completion, lactate concentration was determined.

The 6-MWT distance increased from 420 ±80 m to 519 ±61 m (

< 0.001), and the energy expenditure from 4.4 ±1.4 MET to 6.3 ±1.3 MET (

< 0.001). There was a positive correlation between 6-MWT distance and energy expenditure in the TEST before rehabilitation (

= 0.60,

= 0.005), and after rehabilitation (

= 0.75,

< 0.001). A negative correlation was found between the baseline 6-MWT distance and distance increment in the final 6-MWT (

= -0.66,

= 0.002). The 6-MWT did not induce hyperlactatemia.

The 6-MWT can be used in exercise intensity prescription, especially for determining the individual initial training load, load progression, as well as its correction during follow-up tests.

The 6-MWT can be used in exercise intensity prescription, especially for determining the individual initial training load, load progression, as well as its correction during follow-up tests.

The aim of the study was to present our experience and evaluate the valve-related factors and the incidence of prosthetic valve endocarditis.

This is a retrospective study. Between 2010 and 2018, 36 patients were re-operated on due to prosthetic valve endocarditis The valve-related factors (type, size and position of the prosthetic valve) were analysed.

Thirty-six patients had prosthetic valve endocarditis. The overall hospital mortality was 16.67%. Early vs. late onset prosthetic valve endocarditis mortality was 23.08% vs. 13.04% respectively. The type, size or position of the prosthesis was not associated with prosthetic valve endocarditis. There was a statistically significant difference between occurrence of prosthetic infection between mitral repair and replacement both in mechanical and biological valve groups. The most common infective agent in the early onset group was Staphylococcus aureus, whereas in the late onset group it was Enterococcus faecalis. Out of 13 patients with early prosthetic valve endocarditis, 11 had infection in the perioperative period around primary operation.