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Additionally, the perturbation factor p Q , necessary for the calculation of dose to water from an air kerma calibration coefficient, was determined. The beam quality correction factor [Formula see text] for the chambers varied in the investigated energy range by about 4%-5%, and for five out of six chambers the data could be fitted by a simple logarithmic function, if the half-value-layer was used as the beam quality specifier. Corresponding data using different Monte Carlo codes for the same ion chamber agreed within 0.5%. For the perturbation factor p Q , the data did not obey a comparable simple relationship with the beam quality specifier. The variation of p Q for all ion chambers was in the range of 3%-4%. Compared to recently published data, our p Q data is around 1% larger, although the same Monte Carlo code has been used. Compared to the latest experimental data, there are even deviations in the range of 2%.There has been substantial interest in developing techniques for synthesizing CT-like images from MRI inputs, with important applications in simultaneous PET/MR and radiotherapy planning. Deep learning has recently shown great potential for solving this problem. The goal of this research was to investigate the capability of four common clinical MRI sequences (T1-weighted gradient-echo [T1], T2-weighted fat-suppressed fast spin-echo [T2-FatSat], post-contrast T1-weighted gradient-echo [T1-Post], and fast spin-echo T2-weighted fluid-attenuated inversion recovery [CUBE-FLAIR]) as inputs into a deep CT synthesis pipeline. Data were obtained retrospectively in 92 subjects who had undergone an MRI and CT scan on the same day. The patient's MR and CT scans were registered to one another using affine registration. The deep learning model was a convolutional neural network encoder-decoder with skip connections similar to the U-net architecture and Inception V3 inspired blocks instead of sequential convolution blocks. After training with 150 epochs and a batch size of 6, the model was evaluated using structural similarity index (SSIM), peak SNR (PSNR), mean absolute error (MAE), and dice coefficient. We found that feasible results were attainable for each image type, and no single image type was superior for all analyses. The MAE (in HU) of the resulting synthesized CT in the whole brain was 51.236 ± 4.504 for CUBE-FLAIR, 45.432 ± 8.517 for T1, 44.558 ± 7.478 for T1-Post, and 45.721 ± 8.7767 for T2, showing not only feasible, but also very compelling results on clinical images. Deep learning-based synthesis of CT images from MRI is possible with a wide range of inputs, suggesting that viable images can be created from a wide range of clinical input types.Ag/TiO2 nanostructure arrays were constructed on fluorine-doped tin oxide (FTO) via a controllable hydrothermal route and a magnetron sputtering method with a variety of TiO2 arrays decorated by Ag nanoparticles. Effects of different TiO2 arrays on the microstructure, composition, and optical properties of the samples were revealed. As surface enhanced Raman scattering (SERS) active substrates, we discussed the sensitivity and reproducibility of Ag/TiO2 nanostructure arrays for Rhodamine 6G (R6G) molecule detection. It was found that TiO2 nanosheet (TiO2(S)) array as a supporting made Ag nanoparticles have a uniform and continuous distribution, which achieved much higher SERS signals. The obtained Ag/TiO2(S) substrate had an improved enhancement factor of 4.31 × 105 compared with the other Ag/TiO2 nanostructure arrays of nanorods, nanotubes, and nanotrees. Furthermore, Ag/TiO2(S) active substrate showed good reproducibility with low relative standard deviation values. Such a remarkable SERS activity could be due to the synergistic effect of electromagnetic enhancement and charge transfer enhancement. Moreover, the TiO2(S) array with high-exposed 101 facets provided a large adhesion area and generated a strong interaction with external atoms, which would produce high-density 'hot spots' of SERS.We study the vortex-lattice formation in a rotating Rashba spin-orbit (SO) coupled quasi-two-dimensional (quasi-2D) hyper-fine spin-1 spinor Bose-Einstein condensate (BEC) in the x-y plane using a numerical solution of the underlying mean-field Gross-Pitaevskii equation. In this case, the non-rotating Rashba SO-coupled spinor BEC can have topological excitation in the form of vortices of different angular momenta in the three components, e.g. the (0, +1, +2)- and (-1, 0, +1)-type states in ferromagnetic and anti-ferromagnetic spinor BEC the numbers in the parenthesis denote the intrinsic angular momentum of the vortex states of the three components with the negative sign denoting an anti-vortex. The presence of these states with intrinsic vorticity breaks the symmetry between rotation with vorticity along the z and -z axes and thus generates a rich variety of vortex-lattice and anti-vortex-lattice states in a rotating quasi-2D spin-1 spinor ferromagnetic and anti-ferromagnetic BEC, not possible in a scalar BEC. For weak SO coupling, we find two types of symmetries of these states - hexagonal and 'square'. The hexagonal (square) symmetry state has vortices arranged in closed concentric orbits with a maximum of 6, 12, 18… (8, 12, 16…) vortices in successive orbits. Of these two symmetries, the square vortex-lattice state is found to have the smaller energy.This study aims to evaluate the indices of glandular dose heterogeneity in full-field digital mammography. The distributions of granular dose (GD) in a breast phantom with a skin layer of 4 mm were determined using the Monte Carlo method with simulated X-ray fluence spectra. First, the GD to air kerma (GD/Kair) volume histogram was obtained from the GD distributions, which were indicated by the glandular volume (%) as a function of GD/Kair. The GD indices, namely, the maximum glandular dose (GD2%) and glandular volume percentage (%) receiving at least the mean glandular dose (MGD) (VMGD) were calculated from the GD/Kair volume histogram. Next, the scatter plots of GD2%/MGD and VMGD were drawn as functions of the normalized mean glandular dose (DgN). Finally, (GD2%)i and (VMGD)i were obtained from the relationship between the GD indices and DgN for 596 clinical irradiation cases based on individual irradiation conditions. The values of GD2%/MGD were more affected by breast thickness than glandularity and tube voltage, and they decreased according to the power law of DgN for all the target/filter combinations. The values of VMGD were proportional to DgN and decreased with increase in the compressed breast thickness (CBT). The values of (MGD)i and (GD2%)i for 596 clinical irradiation cases were estimated to range from 0.6 to 3.0 mGy and 1.1 to 7.0 mGy, respectively, and (VMGD)i was in the range 32%-48%. (GD2%)i and (VMGD)i are mainly affected by breast thickness. These indices are useful for the evaluation of glandular dose heterogeneity in mammography.The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus®Plus (PPlus) and Proteus®One (POne), deliver a continuous or a pulsed beam, respectively. In PPlus, scaled (or no) rescanning can be applied, while POne implies intrinsic 'rescanning' due to its pulsed delivery. We investigated the efficacy of these PBS-PT delivery types for the treatment of lung tumours. In general, clinically acceptable plans were achieved, and PPlus and POne showed similar effectiveness.The goal of supporting and directing tissue regeneration requires the design of new, advanced materials, with features like biocompatibility, biodegradability and adequate mechanical properties. Our work was focused on developing a new injectable biomimetic composite material, based on a peptidic hydrogel and calcium phosphates with the aim of mimicking the chemical composition of natural bone tissue. Arg-Gly-Asp-grafted chitosan was used to promote cell adhesion. The obtained composite hydrogel was characterized with differential scanning calorimetry measurements, rheological analysis, field emission scanning electron microscopy, Fourier transform infrared spectroscopy and nuclear magnetic resonance measurements. www.selleckchem.com/pharmacological_epigenetics.html The biological responsiveness was assessed using the MG-63 human osteoblast cell line.High thermal conductivity is an important parameter for nitride-based power electronic and deep-UV light emitters. Especially in the latter case short period superlattices and multicomponent alloys are used and the knowledge of the thermal properties of the binary compounds is sufficient. In-plane and cross-plane thermal conductivity of AlGaN/GaN superlattices were measured by differential two-wire 3ω method in the temperature range from 147 to 325 K. Samples were grown by metalorganic vapor phase epitaxy; the structure quality and accuracy of superlattice structures preparation were verified by means of HRXRD and transmission electron microscopy. It was observed, that value of thermal conductivities decrease with decreasing period thickness, while temperature dependencies differ from each other-in-plane thermal conductivity decreases, and cross-plane-increases with increasing temperature. Callaway method was used for thermal conductivity calculation; dependence of boundary scattering rate on the phonon wavelength was taken into account. Minimum thermal conductivity was added to calculated values to include the influence of high frequency acoustic phonons and optical phonons on the heat transport. Calculations are in good agreement with experimental results.This study examined how different types of social interaction and competitive information in exergaming affect older adults' motivation and attitude toward playing exergames. A 2 (time pre- vs. posttest) × 3 (social interaction play alone vs. play with peer vs. play with youth) × 2 (competition competition informed vs. noncompetition informed) mixed experiment was conducted with 319 Singaporean older adults over 6 weeks through a three-way analysis of variance. Social interaction was found to significantly affect the changes of extrinsic motivation over time, while competitive information affected intrinsic motivation significantly. The results showed significant three-way interaction effects between time, social interaction, and competitive information on older adults' extrinsic and intrinsic motivations. The changes of attitude over time were not affected by either social interaction or competitive information. The findings contribute to aging research and advance the knowledge of potential factors that promote the effective implementation of exergames for community older adults.

Currently, it is unclear which physical characteristics may underpin the change of direction deficit (COD-D). This investigation sought to determine if momentum, speed-, and jump-based measures may explain variance in COD-D.

Seventeen males from a professional soccer academy (age, 16.76 [0.75]y; height, 1.80 [0.06]m; body mass, 72.38 [9.57]kg) performed 505 tests on both legs, a 40-m sprint, and single-leg countermovement and drop jumps.

The regression analyses did not reveal any significant predictors for COD-D on either leg. "Large" relationships were reported between the COD-D and 505 time on both limbs (r = .65 to .69; P < .01), but COD-D was not associated with linear momentum, speed-, or jump-based performances. When the cohort was median split by COD-D, the effect sizes suggested that the subgroup with the smaller COD-D was 5% faster in the 505 test (d = -1.24; P < .001) but 4% slower over 0-10 m (d = 0.79; P = .33) and carried 11% less momentum (d = -0.81; P = .17).

Individual variance in COD-D may not be explained by speed- and jump-based performance measures within academy soccer players.

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