Barnettcummings2974

Evidence-based practice (EBP) is an expectation of medical professionals and is positively received in the dental community. Investigations of evidence-based dentistry (EBD) have discussed its use in broad terms and daily clinical practice, but there is only limited information about its use and barriers with respect to particular dental specialities.

A cross-sectional questionnaire was developed to survey implementation and obstacles to EBP; EBD specific to periodontics; and preferences for types of dissemination of evidence. The target population was active general dentists in Nova Scotia (n = 446). An email link to the questionnaire was distributed to dentists, and reminders were sent 4 and 10 days later.

The response rate was limited (16.6%). Most respondents were comfortable evaluating the growing body of research, although many reported use of low-level evidence, including that from other health professionals or expert opinion. A common barrier to use was insufficient time. Respondents who found se and narrow target population. Specific data related to periodontics may be useful in directing a modified questionnaire to a broader target population. Respondents who are truly interested in EBD and responded to our questionnaire may ultimately benefit the most from our results, where further educational opportunities can be tailored to overcome the identified barriers and aid in more effective translation of evidence-based periodontal decisions in a general dental practice.For almost half a century, Paul Meehl educated psychologists about how the mindless use of null-hypothesis significance tests made research on theories in the social sciences basically uninterpretable. In response to the replication crisis, reforms in psychology have focused on formalizing procedures for testing hypotheses. These reforms were necessary and influential. However, as an unexpected consequence, psychological scientists have begun to realize that they may not be ready to test hypotheses. Forcing researchers to prematurely test hypotheses before they have established a sound "derivation chain" between test and theory is counterproductive. Instead, various nonconfirmatory research activities should be used to obtain the inputs necessary to make hypothesis tests informative. Before testing hypotheses, researchers should spend more time forming concepts, developing valid measures, establishing the causal relationships between concepts and the functional form of those relationships, and identifying boundary conditions and auxiliary assumptions. Providing these inputs should be recognized and incentivized as a crucial goal in itself. In this article, we discuss how shifting the focus to nonconfirmatory research can tie together many loose ends of psychology's reform movement and help us to develop strong, testable theories, as Paul Meehl urged.A pathological increase in vigilance, or hypervigilance, may be related to pain intensity in some clinical pain syndromes and may result from attention bias to salient stimuli mediated by anxiety. During a continuous performance task where subjects discriminated painful target stimuli from painful nontargets, we measured detected targets (hits), nondetected targets (misses), nondetected nontargets (correct rejections), and detected nontargets (false alarms). Using signal detection theory, we calculated response bias, the tendency to endorse a stimulus as a target, and discriminability, the ability to discriminate a target from nontarget. Owing to the relatively slow rate of stimulus presentation, our primary hypothesis was that sustained performance would result in a more conservative response bias reflecting a lower response rate over time on task. We found a more conservative response bias with time on task and no change in discriminability. We predicted that greater state and trait anxiety would lead to a spond and showed slower reaction times to hits than low anxious subjects. This study reveals an important role of trait anxiety in pain vigilance.Agaricus sect. Arvenses includes numerous species that are potential candidates for cultivation, and some have high nutritional and medicinal interests. Between 2012 and 2017, 147 specimens of A. sect. Arvenses were collected in China. For this study, nuc rDNA internal transcribed spacer region ITS1-5.8S-ITS2 (ITS), nuc 28S rDNA (28S), and translation elongation factor 1-alpha (tef1) sequences were used to assess species boundaries of these samples from China. Combined with morphological examination, we recognize 22 species of A. sect. Arvenses from China, of which 12 are known species, one is new record for China, and nine are proposed as new.

Exercise assessments may help predict outcomes for patients diagnosed with lung cancer.

We examined the relationship between pre-diagnosis exercise behavior and clinical outcomes among stage I-IIIA lung cancer patients.

In a retrospective cohort study of patients with stage I-IIIA lung cancer at Kaiser Permanente Colorado who had at least one Exercise Vital Sign (EVS) assessmnt - a questionnaire tool to help promote exercise in chronic disease management - within the year prior to diagnosis, we defined exercise behavior as active (any minutes/week of moderate-to-vigorous intensity physical activity) or inactive (no moderate-to-vigorous physical activity). The outcomes were 1) overall survival (OS); and 2) acute health care utilization (AHCU). We used the Kaplan-Meier method, and Cox proportional hazard, and negative binomial regression models to analyze the effects of exercise on outcomes, adjusting for demographic, socioeconomic, clinical, and lung cancer characteristics.

Among 552 lung cancer patienphysical activity and exercise.

Pre-diagnosis active exercise was associated with better OS following diagnosis with stage I-IIIA lung cancer. Exercise assessments may help predict outcomes, risk-stratify patients for curative intent therapy, and identify those who would benefit from increased physical activity and exercise.Postural responses to similar perturbations of standing balance vary widely within and across subjects. Here, we identified two sources of variability and their interactions by combining experimental observations with computational modeling differences in posture at perturbation onset across trials and differences in task-level goals across subjects. We first collected postural responses to unpredictable backward support-surface translations during standing in 10 young adults. We found that maximal trunk lean in postural responses to backward translations were highly variable both within subjects (mean of ranges = 28.3°) and across subjects (range of means = 39.9°). Initial center of mass (COM) position was correlated with maximal trunk lean during the response, but this relation was subject specific (R2 = 0.29-0.82). We then used predictive simulations to assess causal relations and interactions with task-level goal. VY-3-135 cell line Our simulations showed that initial posture explains the experimentally observed intrasubject variability with a more anterior initial COM position increasing the use of the hip strategy.