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Incubator is a medical device that provide a climatic environment for a newborn and a preterm infant. In the incubator environment, especially, the temperature significantly increases the survival rate of infants. In this study, the incubator air temperature, temperature uniformity and infant skin temperature were measured and controlled with conventional methods and FBG based temperature sensors, and their results and related literature results were compared among them. To this end, in addition to classical sensors, six FBG sensors were used during the measurements, and very close results were obtained between them (R2 = 0.9989). In addition, since real time monitoring of the FBG bands were ensured with a user-friendly interface, measurement processes have been made more ergonomic. In this way, the insulation required for the measurements is also provided perfectly. Measurement errors caused by conventional sensors' properties, which are different for each of them, change over/with time, and also change with different values, have been minimized by using this method. Moreover, in case of increasing the number of sensors for multi-point, continuous and real time temperature measurement in conventional methods, some of the problems such as monitoring of these sensors, obstructing or changing the air flow due to the confusions of these sensors and their cables in the incubator cabinet, and following these, control errors caused by these reasons, and difficulties that may be happened during the infant care and resuscitation procedures have been eliminated. Thus, thermoneutrality in closed incubators were also able to validated and assessed fast and more accurately for preterm and neonates.The heavy metal levels in six walnut cultivars from five geographical zones of Iran were measured. An assessment of risks was conducted by calculating the Target Hazard Quotient (THQ) and Incremental Lifetime Cancer Risk (ILCR) by use of the Monte Carlo simulation method. The highest amounts of As and Pb were reported in Farouj samples. Also, the highest levels of Cr, Zn, Cu and Mn were determined in samples collected from Tuyserkan. Accordingly, 50th and 95th ILCRs for general population due to consumption of walnut were 1.03 × 10-4 and 3.11 × 10-4 (for As), 4.10 × 10-6 and 1.1 × 10-5 (for Cr) and 4.71 × 10-9 and 1.05 × 10-8 (for Pb), respectively. In addition, the 50th and 95th centiles of the HIs for walnut ingestion by Iranians were 1.02 and 2.05, respectively, indicating a minor chance of non-cancer effects. Based on the calculated 95% ILCR, dietary exposure to As through the consumption of walnut poses a risk to Iranian consumer health. However, ILCR values of other heavy metals (HMs) were in acceptable ranges (ILCR less then 1 × 10-4), representing no toxicological concern for consumers. The most significantly influential parameters were determined by sensitivity analysis during the MCS. According to THQ and ILCR methods, concentration was the most sensitive parameters. For THQ method the concentration effects were ranged from 72.4 to 85.1%. Moreover, for ILCR method the effects of concentration in As, Cr, and Pb were 87.1, 79.1 and 83.54%, respectively.

Four and a half million people die globally every year due to traumatic injuries. One major cause of preventable death is bleeding. Blood for transfusion is often unavailable in resource-limited settings, where a majority of trauma deaths occur. Intraoperative autotransfusion (IAT) has been proposed as a safe and feasible lifesaving alternative to allogeneic blood transfusion. However, there is limited knowledge regarding its use among doctors working for international non-governmental organisations (INGOs) in resource-limited settings. The aim of this study was to explore the experiences and perceptions of IAT among INGO-affiliated medical doctors with clinical experience in resource-limited settings.

We conducted semi-structured interviews via telephone or Skype with 12 purposefully sampled surgeons and anaesthesiologists. The interviews were recorded, transcribed verbatim, and analysed using content analysis.

We identified three main themes relating to IAT and bottlenecks preventing the scale-up of i bottlenecks.

Two main minimal access adrenalectomy techniques are available laparoscopic transperitoneal (LTA) and posterior retroperitoneoscopic adrenalectomy (PRA). This study aims to compare these approaches in an updated meta-analysis of randomised controlled (RCT) and non-randomised comparative (NRT) trials.

A systematic search of comparative LTA and PRA studies was performed. Standard demographic and surgical data were recorded. Outcome measures compared included operative time, estimated blood loss (EBL), conversion to open, post-operative pain, time to oral intake and ambulation, early morbidity, hospital length of stay (HLOS) and mortality. Quality of RCTs and NRTs was assessed using Cochrane and ROBINS-I, respectively, and heterogeneity using the I

test. Dichotomous and continuous variables were compared using odds ratios and mean/standard difference. Studies were then combined using the Mantel-Haenszel method. Meta-analysis was performed by fixed- and random-effect models.

Following exclusions, 12 studies were included in the analysis 3 RCTs and 9 NRTs. These reported a total of 775 patients 341 (44%) PRA and 434 (56%) LTA. selleck inhibitor Demographics were similar except for tumour size which was smaller (by 0.78cm) in PRA (p = 0.003). Significant differences in outcome were seen in EBL (18mls less in PRA, p = 0.006), time to oral intake (3.4h sooner in PRA p = 0.009) and HLOS (shorter in PRA by 0.84day, p = 0.001).

This analysis demonstrates that while PRA tends to be performed for smaller tumours it allows for less EBL, earlier post-operative oral intake and shorter hospital stays. In appropriately selected patients, it represents an invaluable tool in the endocrine surgeon's armamentarium.

This analysis demonstrates that while PRA tends to be performed for smaller tumours it allows for less EBL, earlier post-operative oral intake and shorter hospital stays. In appropriately selected patients, it represents an invaluable tool in the endocrine surgeon's armamentarium.

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