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Mesothelioma and Non Asbestos Exposure

The majority of the time, mesothelioma is found on the lung linings as well as the abdomen. This rare cancer can also develop in the linings around the heart or the testes (pericardium).

Asbestos exposure is a major risk factor for mesothelioma. However, some people diagnosed with mesothelioma don't have an asbestos-related history.

Exposure to Asbestos

Asbestos, a rock that is of natural origin, was used in the past for industrial and construction products around the world. Workers in asbestos industries were exposed to asbestos each day. Asbestos fibers can become lodged in the lungs, where they cause progressive lung disease. This is called asbestosis. Over time, these fibers that have been trapped in the lungs could cause mesothelioma. Asbestos is also inhaled or ingested and the risk of mesothelioma and other asbestos-related diseases increases with the length and quantity of exposure.

Most cases of mesothelioma are the result of occupational exposure. Asbestos was used in a variety of trades, including construction, insulation, electrical work, automobile maintenance and pipefitting. Because these professions are predominantly male-dominated 75-80% of mesothelioma cases are diagnosed in men. However, the phasing out of asbestos in the United States and other first-world countries has led to a decrease in exposure on the job. This has led to an increase in cases, with occupational exposure becoming more common.

Non-occupational Mesothelioma can be caused by asbestos is released at the workplace, or is found at home or in schools. It can also be caused by exposure to secondhand asbestos like when a family member is exposed to the clothes of an asbestos-working worker. Highly recommended Internet site of exposure can cause symptoms like chest pain or shortness of breathe, which are often misinterpreted as heart conditions or lung conditions.





Certain studies have linked mesothelioma to non-occupational exposure, but the results vary. The studies were conducted with only a few participants, and the degree of heterogeneity between studies was quite high. It is imperative to conduct additional research in order to confirm the link between asbestos exposure in non-occupational settings and mesothelioma.

Anyone who has been exposed to asbestos in non-occupational settings should consult their doctor about their asbestos history. If they are concerned, they should ask for a mesothelioma examination and referral to a specialist. Mesothelioma specialists can offer patients the best treatment and care options to improve their chances of survival. They will analyze medical records and conduct imaging tests to determine if mesothelioma is present. They will also give guidance on how to file mesothelioma suits to get compensation from asbestos trust funds.

Secondhand Exposure

While asbestos exposure is the primary cause of mesothelioma not the only factor that can cause you to develop this disease. There is evidence to suggest that people who have never been exposed to asbestos or worked in industries with asbestos-related work can still develop mesothelioma. This is referred to as secondary or non-occupational asbestos exposure.

Asbestos fibers are very small and they can stick to clothing, hair skin, and other surfaces. This means that workers can bring the dangerous fibers home in their work clothes and transfer them to family members. The asbestos fibers can cause mesothelioma if they are inhaled or consumed.

This type of mesothelioma is more common in women, and it usually occurs in the lung. It can also affect the chest wall or abdomen. The most frequent symptom is shortness of breath (dyspnea) and it may be associated with other symptoms such as fluid in the lungs or swelling in the scrotum.

The mesothelioma that develops in the lungs is called mesothelioma of the pleural region. Peritoneal mesothelioma is the name for mesothelioma which affects the stomach wall or the chest wall. This kind of mesothelioma may cause a variety of symptoms, including abdominal pain, difficulty in breathing and constipation.

Several studies have reported that people with no history of occupational exposure to asbestos could develop mesothelioma due to exposure to asbestos through secondhand fibers. The people who were affected typically lived with someone who had been exposed to asbestos. They may have touched the clothing of the worker, or they might have had other contact with asbestos.

Veterans are at a higher risk of mesothelioma because asbestos was extensively used in military bases as well as vehicles and ships. The Navy is at a higher risk since asbestos was used in the hull and gun turrets on ships to protect them from fire. Asbestos was also frequently brought home by sailors from their jobs aboard ships that had been infected with asbestos.

Environmental Exposure

A variety of materials have been associated with mesothelioma. However, the disease is often linked to exposure to asbestos. Asbestos is a naturally occurring mineral that was used for a variety of years in manufacturing. The mineral is heat resistant and tough, which makes it ideal for use in insulation, brakes, shingles flooring, and other products. When asbestos is broken up it releases dust that can be breathed in or swallowed. These fibers can remain in the stomach or lungs for years, and trigger mesothelioma symptoms.

The most frequent mesothelioma-related symptoms are breathing difficulties, chest pain and abdominal discomfort. Asbestos exposure can cause these symptoms to persist for up to 60 years. Symptoms can be mistaken for other illnesses, so it is important to see a doctor if you have these symptoms. It is also important to tell your doctor about your previous history of asbestos. This will prevent a faulty diagnosis and ensure that you receive the correct treatment.

Mesothelioma resulting from exposure to asbestos is most common in people who worked directly with the substance however, it can also affect loved ones of those exposed. This is referred to as secondary exposure. Family members may take in asbestos fibers or swallow them on the clothing of a worker, shoes or tools. They may also be exposed to asbestos by someone who brings home these particles on their clothing or hair. This is the reason that mesothelioma sufferers as well as their families must always wash their clothes in a clean manner after working with asbestos.

There is a significant collection of studies that show the connection between exposure to asbestos and mesothelioma. However there are no definitive conclusions yet on the role of other agents. For example there is evidence that the zeolites erionite and chlorosotile can cause mesothelioma. Erionite is found in soil and rocks in some regions of Turkey where pleural mesothelioma rates are high.

Research on the relationship between mesothelioma and nonasbestos exposure is ongoing. Funnel plots have indicated the potential for bias in publications, and the there is a high degree of heterogeneity between studies. However, it is still evident that asbestos exposure from work is the most important risk factor for mesothelioma.

Genetics

Mesothelioma is a rare condition caused by malignant mesothelial cells which expand beyond control and invade surrounding tissues. It can also spread throughout the body through the lymphatic or blood system, and affect other organs. Asbestos is the primary cause, but it is not the sole cause. Other environmental and genetic factors can also trigger the condition.

Certain cases of mesothelioma have occurred in people who did not directly expose themselves to asbestos. They are known as mesothelioma victims who are not employed. These individuals were typically exposed indirectly through the handling harmful household items or clothing by someone who was exposed asbestos in their home. For instance, it's possible for one to be diagnosed with pleural mesothelioma based on the exposure to asbestos fibers in clothing belonging to a loved one. Studies have shown that these kinds of mesothelioma cases tend to have longer periods of latency and are more likely to be diagnosed in wives rather than husbands.

Scientists are currently investigating the possibility that mesothelioma's genetic susceptibility could play a role in the development of the disease. Recent studies have shown the mutation of BAP1 gene increases the risk of mesothelioma in asbestos-exposed patients. This is particularly important, as it could be the basis for improved screening procedures for those at risk of developing mesothelioma.

Researchers have discovered a number genes that are related to mesothelioma. Some of these genes are involved in suppressing tumor growth and are often mutated or altered in mesothelioma patients. These genes include the massive homolog of tumor suppressor 2 (LATS2) and the NF2.

People with mesothelioma in their family are at a higher risk of developing the cancer. This is due to the fact that certain genes, including the BAP1 gene, can be passed down from a parent. Veterans have the highest rates of mesothelioma in comparison to other occupational groups because asbestos was heavily used in the military. People who worked on ships or in the Navy were at the highest risk of developing asbestos-related cancer due to exposure in shipbuilding, insulation, and fireproofing materials.