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In addition, flavonoids were found capable of restoring miRNA and lncRNA expression that is altered during diseases. The optimization of the use of flavonoids as natural epigenetic modulators for chemoprevention and as a possible treatment of PCa and other kinds of cancers could represent a promising and valid strategy to inhibit carcinogenesis and fight cancer.Nutrition is an integral part of economic development, since it influences workers' healthand productivity. This study evaluated the usual nutrient intakes and food sources of workingadults. We conducted a cross-sectional survey that involved 1264 selected working adults aged 19to 59 years old from randomly selected job sectors. Quantitative dietary data was collected by a 2-day, non-consecutive 24 h recall, while a dietary diversity questionnaire was used to assess the typesand frequency of foods consumed. Physical activity was measured using the World HealthOrganization global physical assessment questionnaire. The prevalence of inadequate intakes,defined as the percentage of adults with intakes less than the estimated average requirements (EAR)or acceptable macronutrient distribution ranges (AMDR) were estimated using the PC-Softwarefor Intake Distribution Estimation (PC-SIDE) program. The mean daily energy intake of workingadults was 1768 kcal/day or 74% of the Estimated Energy Requirements (EER) for this age group.The percentage contribution to the total energy of fats (58%) and proteins (34%) were excessivelyhigh. Consumption of fruits and vegetables was only 30% and 40% of the recommended nutrientintake, respectively. Salt intake was 52% above the adequate intake. Nutrient inadequacy was highin almost all nutrients, including iron (99%), folate (97.9%), riboflavin (95.8%), calcium (94.7%),vitamin C (87.3%), and thiamin (76.6%). The top five food sources of energy included rice (35.6%),pork (15.1%), fats and oils (4.7%), chicken (4.4%), and bread (3.8%). Energy and nutrient intakes ofworking adults is extremely sub-optimal due to the consumption of few nutrient-dense foods. Thismay pose a triple burden of malnutrition if left unsolved.Community-based case management for medical aid beneficiaries was implemented in Korea to promote the rational use of medical care and stabilize the financial system. This study investigated the economic impact of community-based case management on reductions in healthcare utilization and costs. This was a program study using a national database to evaluate the effectiveness of community-based case management in changing not only healthcare utilization and costs but also client-centered outcomes using the NHI database and 198 regional databases. A total of 1741 case management clients were included in this study. The case management clients were categorized into three targeted groups and were provided individualized services according to the groups. Client-centered outcomes, such as health-related quality of life (QOL), self-care ability, and having a support system, increased after case management. Healthcare utilization and costs decreased significantly after case management. However, there was no significant difference in the decrease between the groups. An increase in healthcare utilization among medical aid beneficiaries has been observed due to the aging population and an increase in the number of recipients. To reduce healthcare utilization and costs while maintaining the health status of the beneficiaries, it is necessary to expand targeted case management.Over the last few decades the insulating performance of transformer oils has been broadly studied under the point of view of nanotechnology, which tries to improve the insulating and heat dissipation performance of transformer oils by suspending nanoparticles. Many authors have analyzed the thermal and dielectric behavior of vegetable oil based-nanofluids, however, very few works have studied the evolution of these liquids during thermal aging and their stability. In this paper has been evaluated the performance of aged vegetable oil based-nanofluids, which have been subjected to accelerated thermal aging at 150 °C. Nanoparticles of TiO2 and ZnO have been dispersed in a commercial natural ester. Breakdown voltage, resistivity, dissipation factor and acidity of nanofluid samples have been measured according to standard methods, as well as stability. AG-14361 cell line Moreover, it has been analyzed the degradation of Kraft paper through the degree of polymerization (DP). The results have showed that although nanoparticles improve breakdown voltage, they increase the ageing of insulation liquids and dielectric paper.In this study, an experimental investigation was conducted on the mechanical properties of lightweight aggregate concrete (LWAC) with different chopped fibers, including basalt fiber (BF) and polyacrylonitrile fiber (PANF). The LWAC performance was studied in regard to compressive strength, splitting tensile strength and shear strength at age of 28 days. In addition, the oven-dried density and water absorption were measured as well to confirm whether the specimens match the requirement of standard. In total, seven different mixture groups were designed and approximately 104 LWAC samples were tested. The test results showed that the oven-dried densities of the LWAC mixtures were in range of 1.819-1.844 t/m3 which satisfied the definition of LWAC by Chinese Standard. Additionally, water absorption decreased with the increasing of fiber content. The development tendency of the specific strength of LWAC was the same as that of the cube compressive strength. The addition of fibers had a significant effect on reducing water absorption. Adding BF and PANF into concrete had a relatively slight impact on the compressive strength but had an obvious effect on splitting tensile strength, flexural strength and shear strength enhancement, respectively. In that regard, a 1.5% fiber volume fraction of BF and PANF showed the maximum increase in strength. The use of BF and PANF could change the failure morphologies of splitting tensile and flexural destruction but almost had slight impact on the shear failure morphology. The strength enhancement parameter β was proposed to quantify the improvement effect of fibers on cube compressive strength, splitting tensile strength, flexural strength and shear strength, respectively. And the calculation results showed good agreement with test value.