Villarrealglenn0215
Given the republic's promotion of its efforts to modernize Turkey amid its mutual initiatives of nation-building, the empire's histories of providing this foundation are also sometimes overlooked.This work is a summary of the characterization, activities, and ethnobotanical surveys about aromatic and medicinal plants belonging to the genus Mentha in Morocco. The Mentha species investigated are Mentha pulegium, Mentha spicata, Mentha viridis, Mentha suaveolens, Mentha longifolia, Mentha gattefossei, Mentha rotundifolia, and Mentha vulgare, with M. pulegium being the most studied species. M. spicata and M. viridis are poorly explored even though they are daily consumed by Moroccans in tea infusions. The elucidated factors affecting the composition of Mentha essential oils are fertilization, drying conditions, mechanical impedance, NaCl stress, and Gamma irradiation. Investigation of the activities of the Mentha species showed that the main interest was dedicated to addressing the antibacterial effect towards gram+ and gram- bacteria. Essential oils of Mentha species exhibited antifungal, antiviral, antioxidant, insecticidal, licidal, niticidal, allelopathic, antidiabetic, derma-protective, and anticorrosive activities. The ethnobotanical surveys revealed that Mentha species are used in seven regions Tafilalet, High Atlas, Fez-Boulemane, Taounat, Oujda, Ouazzane, and Rabat. By calculating the Jaccard index, the highest degree of similarity was found between Tafilalet, Rabat, and Oujda regions. The wide use of the Mentha species in Morocco highlights the high ethnobotanical value of the genus.Undergraduate student, especially first-year students face challenges in the new found academic environment. Critical thinking (CT) has been found to be effective in managing negative experiences. Earlier literature found Emotional intelligence (EI) is accounted for variance in critical thinking (CT) skill irrespective of the gender. However, there is scarcity of research on the relationship between EI and CT disposition with respect to gender. The present research intended to study the effect of EI on CT disposition of students in the transition phase with gender as a moderator. 500 first-year undergraduate students from West Bengal (eastern part of India) were selected to fill up assessment tools; the Profile of Emotional Competence (Brasseur et al., 2013) and Critical Thinking Disposition Assessment (Ricketts & Rudd, 2005). Structural Equation Model (SEM) was followed using AMOS adopting maximum likelihood approach. Path analysis revealed an accepted model fit establishing EI to have significant effect on CT disposition. However, this effect was not moderated by gender. The present research might be helpful in generating awareness regarding the importance of EI and training for developing disposition of CT among college fresher's well-being and emotional health. The study has highlighted the non-significant moderating role of gender in relation to EI and CT disposition that was missing in the existing literature.[This corrects the article DOI 10.1016/j.heliyon.2020.e05210.].
Hypertension induced kidney damage is often associated with fibrosis and tubular apoptosis. Double-stranded protein kinase (PKR) is a well recognized inducer of inflammation and apoptosis. However, role of PKR in hypertension coupled renal damage is still not explored. Therefore here we sought to investigate the role of PKR in the pathogenesis of L-NAME induced hypertension and renal damage in Wistar rats and the underneath molecular mechanism.
L-NAME (40 mg/kg, p.o) and imoxin (0.5 mg/kg, i.p) was given to Wistar rats for 4 weeks. Increased eNOS expression, serum creatinine, BUN and changes in mean arterial pressure confirmed for hypertensive renal damage. Western blot and immunohistochemistry was carried out for PKR and markers for fibrosis and apoptosis. Morphological alterations were assessed by H&E staining. Selleck XL184 Sirius red and Masson's Trichrome staining was performed for collagen and fibrosis. TUNEL assay was done for tubular cell death and apoptosis.
Increased expression of PKR and its downstream markers were reported in L-NAME rats, attenuation was observed with imoxin treatment. L-NAME treated rats showed a significant increase in MAP, serum calcium, creatinine and BUN along with the significant morphological changes, attenuation was reported with the imoxin treatment.
PKR is a core contributor in the pathogenesis of L-NAME induced renal damage and tubular apoptosis. Therapeutically targeting of PKR could be an attractive approach to treat the renal complications associated with hypertension.
PKR is a core contributor in the pathogenesis of L-NAME induced renal damage and tubular apoptosis. Therapeutically targeting of PKR could be an attractive approach to treat the renal complications associated with hypertension.A derivative-free conjugate gradient algorithm for solving nonlinear equations and image restoration is proposed. The conjugate gradient (CG) parameter of the proposed algorithm is a convex combination of Hestenes-Stiefel (HS) and Dai-Yuan (DY) type CG parameters. The search direction is descent and bounded. Under suitable assumptions, the convergence of the proposed hybrid algorithm is obtained. Using some benchmark test problems, the proposed algorithm is shown to be efficient compared with existing algorithms. In addition, the proposed algorithm is effectively applied to solve image restoration problems.The functional renal epithelium is composed of differentiated and polarized tubular cells with a strong actin cortex and specialized cell-cell junctions. If, under pathological conditions, these cells have to resist higher kidney osmolarity, they need to activate diverse mechanisms to survive external nephrotoxic agents such as inflammation and oxidative stress. Wine pomace polyphenols exert protective effects on renal cells. In this study, two wine-pomace products and their protective effects upon promotion and preservation of normal cell differentiation and attenuation of oxalate-induced type II epithelial mesenchymal transition (EMT) are evaluated. Treatment with gastrointestinal and colonic bioavailable fractions from red (rWPP) and white (wWPP) wine pomaces, both in the presence and the absence of oxalate, showed similar cell numbers and nuclear size than the non-treated differentiated MDCK cells. Immunofluorescence analysis showed the reduction of morphological changes and the preservation of cellular junctions for the rWPP and wWPP pre-treatment of cells exposed to oxalate injury.