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8%) patients respectively resulting in an at the end of six months of induction immunosuppressive treatment. The most common class of lupus nephritis was class IV, 7 patients, followed by class IV+V, and class V, 6 patients in each respectively. The mean 24-hour urinary total protein, serum albumin and serum creatinine were 2492±1051 mg, 2.1±0.4 g/dl, and 0.9±0.1 mg/dl respectively. Adverse events were observed in 6 (25%) patients.

Our study shows that good proportions of patients with lupus nephritis achieve clinical remission at the end of six months of induction immunosuppressive treatment with induction therapy, however, at the cost of some tolerable side effects.

Our study shows that good proportions of patients with lupus nephritis achieve clinical remission at the end of six months of induction immunosuppressive treatment with induction therapy, however, at the cost of some tolerable side effects.

Medical doctors have profound influence on other health professions including physiotherapist as they are at the top of the pyramid of healthcare profession. There is a lack of knowledge of physiotherapy among medical doctors. They may not be knowing of all physiotherapy services and practice. The objective of this study was to find adequate knowledge of physiotherapy practice among medical interns in a tertiary care hospital.

A descriptive cross-sectional study was conducted on medical interns of a tertiary hospital of Kathmandu between 21st March - 20th May 2021, after taking ethical approval from the Institutional Review Committee. A convenient sampling method was used and sample size was calculated to be 94. A structured questionnaire was used to collect the demographic details and knowledge of Physiotherapy. Data was analyzed using statistical package for the social sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.

The knowledge of physiotherapy practice was seen adequate among 16 (17%) (95%Confidence Interval = 9.41-24.59) medical interns. Physiotherapy is effective in reducing pain was acknowledged by 89 (97.4 %), 61 (64.9 %) had knowledge about conditions treated by physiotherapy, 55 (58.5 %) had knowledge that physiotherapy treatment follows definite treatment protocol and 26 (27.7 %) had knowledge that exercise prescription is done in physiotherapy.

The prevalence of adequate knowledge is less in our study which is similar to other studies done in similar settings. Therefore, there is a need of educating the future medical doctors about physiotherapy, thereby reaching a better patient care.

The prevalence of adequate knowledge is less in our study which is similar to other studies done in similar settings. Therefore, there is a need of educating the future medical doctors about physiotherapy, thereby reaching a better patient care.

Urinary incontinence is an involuntary passage of urine. The aim of the study was to find the prevalence of urinary incontinence among pregnant women in the third trimester of pregnancy at a tertiary care center.

This descriptive cross-sectional study was conducted in a tertiary care center from March 2021 to May 2021. Ethical approval was obtained from the Institutional Review Board (reference number 854/2077/78). Convenience sampling method was used. A descriptive analysis of socio-demographic profile and urinary incontinence symptoms were recorded on International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short Form questionnaire and analysis were done using Statistical Package for Social Sciences 27. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

Among 277 pregnant women admitted in the antenatal ward, urinary incontinence was present in 26 (9.4%) (95% Confidence Interval= 5.96-12.84). Among them, stress urinary incontinence 16 (61%) was most common followed by mixed incontinence 6 (23%). Majority of them 18 (69.3%) had small leaks with almost all 25 (96.2%) having only a mild to moderate impact on the quality of life. Majority 197 (71.2%) had features of lower urinary tract syndrome.

Our study showed similar prevalence of urinary incontinence compared to other international studies.

Our study showed similar prevalence of urinary incontinence compared to other international studies.

Alcohol dependence syndrome is an important and major public health issue seen in our community and health center. It is mostly associated with different mental health problems and psychiatric co-morbidities. This study aims to find out the prevalence of depression among alcohol dependence syndrome in a tertiary care hospital.

A descriptive cross-sectional study was conducted over one year from April 15, 2020, to February 15, 2021 at a tertiary care hospital. The ethical approval was obtained from the Institutional Review Committee of Nobel Medical College (reference number 409/2020). Convenience sampling method was used. The patients admitted for alcohol use and related problems in the Psychiatry Department, Nobel Medical College Teaching Hospital, Biratnagar were included. Data entry was done using Microsoft Excel and statistical analysis was done by using Statistical Packages of Social Sciences Version 16.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage.

The prevalence of depression in patients with Alcohol Dependence Syndrome was 17 (16.3%) (95% Confidence Interval= 9.20-23.39) . The patients suffering from depressive disorder male and female were 16 (94.1%) and 1 (5.8%) respectively. The participants with Alcohol Dependence Syndrome with no other comorbid psychiatric disorders were found to be 60 (57.7%).

Psychiatric comorbidity was found to be common in alcohol dependent people among which depression was found to be most common.

Psychiatric comorbidity was found to be common in alcohol dependent people among which depression was found to be most common.

Menstrual disorders are problems faced by women in their reproductive period, which affects their day-to-day activities and the quality of life and sometimes can be an indicator of serious pathology. There are various types of menstrual disorders with dysmenorrhea being the commonest and most distressing. Health, sense of wellbeing and quality of life can be improved because of early detection and treatment for these disorders. The study aimed to find out the prevalence of dysmenorrhea among the nursing staff of a tertiary care center.

A descriptive cross-sectional study was carried out from September 2020 to November 2020 among the nursing staff of a tertiary care hospital. Ethical approval was taken from the Institutional review committee of Kathmandu Medical College and Teaching Hospital (reference number 1709202003). A convenient sampling technique was used. A pre-structured questionnaire was used for data collection. The subjects were asked to fill the questionnaire anonymously after taking consent. Statistical analysis was done using the Statistical Package for the Social Sciences. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.

Out of 212 participants, 165 (77.8%) (95% Confidence Interval = 72.21-83.39) participants reported pain during menstruation. Of which, 61 (36.97%) participants reported abdominal pain.

The prevalence of dysmenorrhea was high among the nursing staff of a tertiary care centre which was similar to the findings of other studies done in similar settings.

The prevalence of dysmenorrhea was high among the nursing staff of a tertiary care centre which was similar to the findings of other studies done in similar settings.

Evan's index is useful to objectively see if ventricles size is abnormal especially in borderline cases of hydrocephalus. Studying ventricular size in CT scan is essential in every pathology of the brain. Use of objective parameters to define hydrocephalus helps us not only to diagnose a case but also follow up the case following treatment. RRx-001 concentration The aim of this study was to find out the mean even index among patients visiting the department of radiology of a tertiary care hospital.

A descriptive cross-sectional study was conducted at a tertiary care hospital from 1st january 2020 to 31st December 2020. Ethical clearance was obtained from the Institutional Review Committee of Upendra Devkota Memorial Neurological and Allied Sciences (reference number 116/2021). Computed tomography scans were done for various reasons in the hospital over a one year period and reported normal by the radiologists were included in the study. Convenient sampling was done. Statistical analysis was done using Statistical Package for the Social Sciences. Point estimate at 95% Confidence Interval was calculated along with mean and standard deviation for continuous data.

In this study, among the 216 cases, the mean Evan's index was found to be 0.20±0.04.

The mean evan's index in our study population was lower than the normal cut-off value.

The mean evan's index in our study population was lower than the normal cut-off value.NA.

End-stage renal disease patients are in rising trend globally, and they have been found to occur predominantly in developing countries. Many studies have been published before, within and across the countries, to know the clinicodemographic profile of end-stage renal disease patients. However, no such studies were done in Chitwan, Nepal. This study's main objective was to find the prevalence of newly diagnosed end-stage renal disease patients.

A hospital-based descriptive cross-sectional study was carried out in the Department of Nephrology from May 2016 to April 2019. Convenient sampling was done, and all the consecutive new end-stage renal disease patients were included in the study. The ethical approval was taken from the Institutional Review Committee (reference number. 2016/COMSTH/IRC/042). The prevalence and demographic profile of new end-stage renal disease patients were studied. The data were analyzed with appropriate statistical tools.

A total of 250 new end-stage renal disease patients were found among 2200 admitted patients. The prevalence of new end-stage renal disease was found to be 250 (11.36%). Out of 250 patients, males were 156 (62.4%), and females were 94 (37.6%). The mean age was 49.6±15.5 years. The commonest cause of the incident end-stage renal disease was Type 2 Diabetes mellitus 89 (35.6%).

The prevalence of new end-stage renal disease was found to be quite high. The commonest cause of the incident end-stage renal disease was Type 2 Diabetes Mellitus.

The prevalence of new end-stage renal disease was found to be quite high. The commonest cause of the incident end-stage renal disease was Type 2 Diabetes Mellitus.The practice of medicine has started since the existence of humankind on the earth. But the commencement of scientific and evidence-based medicine cannot be traced back so far. The insight we are getting from the current medical science is the output of the laborious effort and contributions made by people before us. The statement stating 'we learn from our past' is in perfect resonant with the practice of clinical medicine. Those past experiences or findings which are scientifically cataloged are crucial in the advancement of modern medicine. The countless researches conducted in various aspects of medical science prove to be strong evidence of our past achievements. Many people's contribution to such research activities in the medical field has taken us this far in modern medicine. In the pool of such people, medical students who are in the early phase of pursuing their career in medicine have also contributed a lot to medical research time and again.