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yndrome decreased; that was accompanied by positive dynamics of neurovegetative (

<0.01) and psychoemotional (

<0.01) symptoms (Kupperman scale), indicators of anxiety (

<0.01) and depression (

<0.05) (HADS scale), situational anxiety (

<0.01) (Spielberger-Khanin scale), the severity of mental and somatic signs of anxiety by 51.0% (Hamilton scale).

The proposed rehabilitation complex helps to reduce the functional tension of the higher nervous system autonomic centers and to increase the nonspecific body reactivity. This allows to recommend the proposed course for the rehabilitation of this patients' category.

The proposed rehabilitation complex helps to reduce the functional tension of the higher nervous system autonomic centers and to increase the nonspecific body reactivity. This allows to recommend the proposed course for the rehabilitation of this patients' category.Chronic pain syndromes in the neck and shoulder girdle are one of the important clinical problems due to their high prevalence. In addition, it's of great interest to study the mutual influence of the musculoskeletal system pathology, balance organs and dentoalveolar system due to the possible negative impact of these structures on each other which surely affects the treatment timing and its results.

To develop a diagnostic algorithm and a comprehensive program for the treatment and rehabilitation of patients with cervicobrachialgia combined with pathological dental occlusion.

The study involved 90 persons of both genders aged 18 to 55 years consisted of 3 clinical study groups (25 patients) and one control group (15 healthy persons). MRTX0902 in vivo The clinical groups included 75 patients with chronic myofascial pain syndrome in the neck and shoulder girdle resistant to drug therapy, with temporomandibular joint (TMJ) dysfunction and/or pathological dental occlusion (PDO). The groups were formed depending on the chosen d to identify etiology-pathogenesis links between these conditions. These methods are also applicable for quality control of treatment.

Thus, as a study result the diagnostic algorithm was developed; it allows to determine the relationship of pharmacoresistant pain syndrome of the cervicobrachial region with dental pathology at high degree of accuracy; and a comprehensive interdisciplinary approach to the therapy and rehabilitation of this combined pathology was proposed.

Thus, as a study result the diagnostic algorithm was developed; it allows to determine the relationship of pharmacoresistant pain syndrome of the cervicobrachial region with dental pathology at high degree of accuracy; and a comprehensive interdisciplinary approach to the therapy and rehabilitation of this combined pathology was proposed.Dissatisfaction with night sleep occurs in 45% of the population. Chronic insomnia is one of the most common sleep disorders. The incidence of insomnia is estimated at 9-15%. The clinical importance of insomnia is determined by the negative impact it has on social aspects, economic performance and human health. Taking into account the prevalence of insomnia in the population and its social importance the correct diagnosis and effective treatment of insomnia is clear.

To assess the sleep quality dynamics in patients with chronic insomnia getting the complex spa treatment with the inclusion of transcranial magnetic therapy (TCMT).

It was examined 122 patients (mean age 54.0±0.92 years) with a verified diagnosis of chronic insomnia; 68.9% were women and 31.1% were men. The patients were randomized into 2 groups the main group included 62 patients who received a spa complex and TCMT; the comparison group included 60 patients who received an identical treatment complex without TCMT. All patients were evaluated icators according to PSG data in patients with chronic insomnia.The disability of post-stroke patients is one of the most important problems of the modern medical community requiring the improvement of existing rehabilitation technologies through the wider use of non-drug treatment methods among which the most accessible are various modifications of reflexotherapy.

To evaluate the effectiveness of the combined reflexology technique, including the combined use of classical acupuncture, su-jok and cranial acupuncture in the early rehabilitation of patients after ischemic stroke.

Examination and course of early neurorehabilitation were carried out in 80 patients aged 47-78 years. Effectiveness evaluation of the different methods of reflexotherapy was carried out in 4 groups (20 patients each) comparable by age, gender and severity of stroke. In the main group the basic rehabilitation complex was supplemented by the combined use of classical, cranial acupuncture (with symmetrical stimulation of 7 main zones) and su-jok. Patients of the 1st comparison group additionally undterized by high clinical effectiveness that contributing to the regression of neurological symptoms and improvement of the psycho-emotional status of post-stroke patients which has a beneficial effect on their adaptation to the daily life.

Improvement of neurorehabilitation technologies using combined techniques of reflexotherapy in the acute period of ischemic stroke is characterized by high clinical effectiveness that contributing to the regression of neurological symptoms and improvement of the psycho-emotional status of post-stroke patients which has a beneficial effect on their adaptation to the daily life.In recent years, with the improvement of the sensitivity of examination equipment and the change of people's living environment and diet, the rate of thyroid cancer has risen rapidly, which has increased nearly five folds in 10 years. The pathogenesis, clinical manifestation, biological behavior, treatment and prognosis of thyroid carcinoma of different pathological types are obviously different. Papillary thyroid carcinoma (PTC) can develop at any age, which accounts for about 90% of thyroid cancer. It progresses slowly and has favourable prognosis, but lymph node metastasis appears easily. Whether PTC is accompanied by lymph node metastasis has an important impact on its prognosis and outcome. The Raf murine sarcoma viral oncogene homolog B(BRAF)gene mutation plays a crucial role in PTC lymph node metastasis. Having an in-depth understanding of the specific role and mechanism of BRAF gene mutation in PTC is expected to provide new ideas for diagnosis and treatment of PTC.

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