Sotosheppard6352

It was on 31st December 2019, that a cluster of pneumonia cases was reported to the World Health Organization (WHO) by China. The initial investigations revealed the cases to be due to a previously unknown "never before seen strain of coronavirus". Coronaviruses are a group of viruses, which are normally present among animals such as cows, bats, camels and cats. The disease was officially named COVID-19 by WHO on 11th February 2020. The International Committee on Taxonomy of Viruses named the virus as SARS-CoV-2 due to its resemblance to SARS coronavirus. According to WHO's Situation Report-28 as of 17th February 2020, globally there were 71,429 confirmed cases, which included both laboratories confirmed and clinically diagnosed cases (applicable only to Hubei province of China). Selleckchem Lysipressin Cases are clinically diagnosed based on their signs and symptoms and chest x-rays without laboratory testing. More than 99% of these are in China i.e. 70,635 and 794 are outside China. The cases reported outside of China belong to 25 countries in various regions of WHO China having the epicenter of the disease bears the greatest brunt, with 1772 deaths. The three deaths outside China have been reported in Philippines, Japan and France. The case fatality rate of COVID-19 ranges between 2-3% A wide spectrum of disease, ranging from mild to severe, has been reported in confirmed cases of COVID-19. Respiratory symptoms, fever, cough, dyspnoea, myalgia, fatigue, breathing difficulties and bilateral lung infiltrates on C.T are common findings. Pakistan so far has not reported any confirmed case of COVID-19. Government is showing its commitment towards the threat of importation. This novel coronavirus, called as a "devil" by Chinese Prime Minister, Xi Ping is really an enigma.Gastric perforation is among one of the common indications for a laparotomy. It can occur as a result of an erosive ulcer, long term usage of NSAIDs and malignancy among other causes. Here we report a case of a 70-year-old man with an invasive fungal infection as a cause of his gastric perforation based on histopathological evidence. Although very rare it should be kept in mind as an etiological factor of upper GI perforation especially in old age patients. To the best of our knowledge no previous data on such an association has been reported in our country.Malaria is a common public health problem which may have high morbidity and mortality. Physicians should be aware of the unusual presentations of this disease so that it can be timely diagnosed and treated. Herein we are presenting a case of falciparum malaria who presented to the hospital with carpopedal spasm and tetany. We will subsequently discuss mineral homeostasis and the mechanisms of hypocalcaemia in falciparum malaria and the dysregulation of calcium, phosphorus and magnesium metabolism.Paediatric thoracic tumours resection is one of the most difficult procedure for any anaesthetist. Paediatric population is different from adults in many aspects, as they have small thoracic volume and more compressible mass effect on their airway and vascular structures. we are reporting a case of a huge paediatric thoracic tumour resection occupying the left thoracic cavity. The possible mechanism, consequences, prevention and management discussed in this report.Under the banner of cancers of unknown primary origin (CUPs), neuroendocrine tumours account for less than five percent of the neoplasms. The clinical manifestations and management depend upon the tumour's grade and differentiation and its site of growth. At times, despite of aggressive search for primary origin, cancer remains hidden. Herein, we present a case of a middle-aged woman who presented to our tertiary set-up with complaints of abdominal pain and distension. After a series of radiologic and interventional investigations including positron emission tomography with liver biopsy and immunohistochemical analysis, a diagnosis of the welldifferentiated neuroendocrine tumour was made, located in the right lobe of the liver. However, the primary origin could not be identified. The patient was managed with trans-arterial chemoembolization (TACE) followed by hepatic resection and was followed biennially afterwards. In our case, hepatic metastasis was treated with chemoembolization and stagedresection and provided a good prognosis to the patient. Our case is unique as only a few case reports have been published with following presentation and documentation of efficacious treatment is needed to contribute to the literature. Proper trials with exteriorization of bowel and radiological imaging is necessary to stage the primary tumour, even if end result is in vain. This will help to further improve the prognosis.Behcet's disease (BD) presents as uncommon inflammatory disorder involving multiple systems, identified by longstanding relapsing path. Its chief manifestations are oral and genital ulcers together with involvement of the eyes, skin and joints. Neurological and vascular complications are significant. We report a case of a twenty-four years old young male who presented with headache, fever, and vomiting along with decreased vision; and repeated oral and genital ulcers. Diagnosis of BD complicated with cerebral venous thrombosis (CVT) was made. He was treated with corticosteroids, immunosuppression therapy and colchicine along with anticoagulation therapy. He responded well to the given treatment. Cerebral venous thrombosis complications in with BD can lead to serious consequences. Early recognition and treatment may lessen poor outcomes.Background Dengue infection is a deadly global pandemic due to its fatal nature, being emerged from mild stage to turn into more severe stages and consequently causing casualties. it upsurges various phases, namely subclinical infection, undifferentiated febrile fever, Dengue fever (DF) and devastating states which often ends to life, they are Dengue haemorrhagic fever (DHF) and Dengue shock syndrome (DSS). Dengue infection is a mosquito born disease which has engulfed many regions in general and tropical zone in particular, causing many casualties and has posed a threat to humanity, demanding strategies to resolve the global issue. It is reported that 50-200 million people fall prey to it globally by dint of its causative agents and imperative to mention that over proportional are the minor among the victims. Because of awful joint pain dengue fever is also named break bone fever. The common indicator in infected individuals is thrombocytopenia, coagulopathy and vasculopathy. Apart from supportive therapy, no aphoristic therapy has been introduced so far, however care may prove rescuer.