Sextonluna5707
0 ± 107.4 µm, P = 0.038, respectively). The NF1 group had significantly higher hexagonality in comparison with controls (55.7 ± 6.5 versus 50.5 ± 9.9%, P = 0.025). CCT was similar between the two groups (P = 0.955).
Our results show that corneal endothelium has more favorable morphological characteristics in NF1 patients compared to healthy individuals of the same age.
Our results show that corneal endothelium has more favorable morphological characteristics in NF1 patients compared to healthy individuals of the same age.
This study aimed to share our experience in the hospital cornea retrieval program as a new eye bank.
This was a retrospective study conducted in a tertiary care institute from August 26, 2019 to March 22, 2020. The medical and eye bank records were analyzed for hospital mortality, mortuary records, and donors approached. The corneal collection was divided between Voluntary (received from voluntary calls), HCRP (cornea received from hospital deaths), and Medico-Legal Cases (received from MLC deaths in hospital) to see the trend of donation and utilization over time.
During the study period, 154 corneas (77 pairs) were collected. The HCRP provided a major source of corneas 58.4% (90 corneas) as compared to voluntary 19.5% (30 corneas) and MLC 22.1%(34 corneas). There were younger tissues in MLC than HCRP donors, and older tissues in Voluntary donors, and the difference was statistically significant. There was no significant difference in the quality of optical grade tissues and the utilization of corneas for transplants between the three groups. Post hoc analysis showed more non-optical tissues in the voluntary donations (P = 0.004), maximum donors with medical contraindications in the HCRP group (P = 0.001), and time-lapse in corneal retrieval in MLC cases (P = 0.0001). Of these 154 corneas, 78 (50.6%) were assessed as suitable for transplantation, of which 59 (75.6%) tissues were optical grade tissues. The overall utilization was 39.6%.
HCRP is indeed challenging for a new eye bank, but proper understanding and implementing strategies may help for good utilization of tissues.
HCRP is indeed challenging for a new eye bank, but proper understanding and implementing strategies may help for good utilization of tissues.
Cognizant and well aware medical and nursing students are expected to influence and positively mold the eye donation rates in India. Keeping this in view, this study was designed to assess and compare eye donation awareness among medical and nursing students.
A cross-sectional and comparative study undertaken on the occasion of eye donation fortnight among 112 medical and 115 nursing students. A pretested semi-structured questionnaire on eye donation was given to each student after getting informed consent. The software used for analysis of data was SPSS version 22.0.
All the medical students and 91.3% of nursing students (P < 0.0016) had heard about eye donation. Eye donation fortnight is celebrated every year to create awareness was known to 42% of medical students and 29.5% of nursing students (P < 0.05). Television, newspaper, magazines, and posters were found to be important sources of information in both groups. Eye donation can give vision to the blind was the primary motivational force both among medical and nursing students (P < 0.001). The ideal time of eye donation is within 6 h of death was known to 69% of medical students and 60.9% nursing students. Lack of awareness and objection of family members are the two significant perceived responses to non-donation in both groups. 88.4% of medical students and 79.1% of nursing students are willing to donate their eyes in future.
The awareness of eye donation among medical students is better than nursing students. However, the willingness to pledge their eyes is almost equal in both groups.
The awareness of eye donation among medical students is better than nursing students. However, the willingness to pledge their eyes is almost equal in both groups.
The aim of this study was to explore whether prolonged and consistent face mask use might be associated with worsening of dry eye symptoms in patients with dry eye disease (DED).
Subjects with a previous diagnosis of DED. Their OSDI scores were compared with those recorded in Fall 2019 using the Wilcoxon paired test. Participants were stratified by face mask use heavy (Group A) or standard (Group B) face mask users. Heavy use was defined as wearing any type of face mask for at least 6 hours a day, at least 5 days per week in the last 2 months.
67 subjects (mean age 45.27 ± 10.06 SD years, 40% males and 60% females). Median OSDI score in Fall 2019 18.75. Median OSDI in Spring 2020 20.83. The Hodges-Lehmann median difference was 2.09 (95% CI [1.05, 4.17]) (P < 0.0001). The population was then stratified into heavy and standard face mask users Group A included heavy users (31 subjects; mean age 42.81 ± 10.48 SD years; 35% males and 65% females), Group B included standard users (36 subjects; mean age 47.39 ± 9.31 SD years; 44% males and 56% females). The Hodges-Lehmann median difference was 5.21 (95% CI [3.13, 7.29]) in Group A (P < 0.0001), and 1.04 (95% [0],[ 2.08]) in Group B (P = 0.0177).
Prolonged and consistent face mask use is associated with an increase in OSDI scores. selleckchem Whether face mask use is responsible for the worsening of symptoms of DED remains to be elucidated.
Prolonged and consistent face mask use is associated with an increase in OSDI scores. Whether face mask use is responsible for the worsening of symptoms of DED remains to be elucidated.
The aim of this study was to investigate the role of inflammation in the pathogenesis of idiopathic intracranial hypertension (IIH) using the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as inflammation markers.
The files of 33 IIH patients and 33 controls were screened for this retrospective study. For each patient, the NLR and PLR values were calculated using a single fasting blood sample. For both eyes, papilledema (PE) grades, best-corrected visual acuity (BCVA), retinal nerve fiber layer thickness (RNFLT), and ganglion cell layer thickness (GCLT) measurements were recorded along with the demographic data, including body mass index (BMI), and complete neurological and ophthalmological findings. Comparisons between the two groups and between the IIH patients with and without PE were made. The associations of NLR and PLR with all other parameters were analyzed independently from age, gender, and BMI.
NLR and PLR were higher in patients with IIH than controls (P < 0.05).