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Among NAT patients the corresponding survival rates were 52% and 45% and among those undergoing upfront surgery 45% and 40%, respectively. This novel prognostic score combining CRP and CA19-9 serves as a useful preoperative tool estimating survival.Polarization of electromagnetic waves plays an extremely important role in interaction of radiation with matter. In particular, interaction of polarized waves with ordered matter strongly depends on orientation and symmetry of vibrations of chemical bonds in crystals. In quantum technologies, the polarization of photons is considered as a "degree of freedom", which is one of the main parameters that ensure efficient quantum computing. However, even for visible light, polarization control is in most cases separated from light emission. In this paper, we report on a new type of polarization control, implemented directly in a spintronic terahertz emitter. The principle of control, realized by a weak magnetic field at room temperature, is based on a spin-reorientation transition (SRT) in an intermetallic heterostructure TbCo2/FeCo with uniaxial in-plane magnetic anisotropy. SRT is implemented under magnetic field of variable strength but of a fixed direction, orthogonal to the easy magnetization axis. Variation of the magnetic field strength in the angular (canted) phase of the SRT causes magnetization rotation without changing its magnitude. The charge current excited by the spin-to-charge conversion is orthogonal to the magnetization. As a result, THz polarization rotates synchronously with magnetization when magnetic field strength changes. Importantly, the radiation intensity does not change in this case. Control of polarization by SRT is applicable regardless of the spintronic mechanism of the THz emission, provided that the polarization direction is determined by the magnetic moment orientation. The results obtained open the prospect for the development of the SRT approach for THz emission control.To evaluate the effectiveness of a calcium silicate/phosphate fluoridated tooth paste and a serum compared with a toothpaste containing hydroxyapatite on protecting the enamel after interproximal reduction against demineralization. 3 sets of eleven incisors were created. The teeth underwent interproximal enamel reduction (IER) of 0.5 mm. Each set was allocated to one of three groups (1) Brushing without toothpaste (control group); (2) Vitis toothpaste + Remin Pro; (3) Regenerate toothpaste + Regenerate Serum. The agents were applied three times a day and specimens subjected to demineralization cycles for 30 days. buy Brigatinib The weight percentages of calcium (Ca) and phosphorous (P) were quantified by X-ray microfluorescence spectroscopy. Surface microhardness measurements and electron scanning microscopy (SEM) observations were made. Ca data and the Ca/P ratio were significantly higher in Group 3 than the other groups (p 0.017). Group 3 showed significantly higher microhardness values (p less then 0.05) than Group 1. No significant differences were found for other comparisons between groups (p less then 0.05). SEM images showed less demineralization in Group 3. The application of a calcium silicate/phosphate fluoridated tooth paste (Regenerate advance) and a dual serum (Regenerate advance enamel serum) protect the enamel with interproximal reduction against demineralization. Therefore, this treatment could be used to prevent the dissolution of hydroxyapatite after IER.Motor learning is a lifelong process. However, age-related changes to musculoskeletal and sensory systems alter the relationship (or mapping) between sensory input and motor output, and thus potentially affect motor learning. Here we asked whether age affects the ability to adapt to and retain a novel visuomotor mapping learned during overground walking. link2 We divided participants into one of three groups (n = 12 each) based on chronological age a younger-aged group (20-39 years old); a middle-aged group (40-59 years old); and an older-aged group (60-80 years old). Participants learned a new visuomotor mapping, induced by prism lenses, during a precision walking task. We assessed retention one-week later. We did not detect significant effects of age on measures of adaptation or savings (defined as faster relearning). link3 However, we found that older adults demonstrated reduced initial recall of the mapping, reflected by greater foot-placement error during the first adaptation trial one-week later. Additionally, we found that increased age significantly associated with reduced initial recall. Overall, our results suggest that aging does not impair adaptation and that older adults can demonstrate visuomotor savings. However, older adults require some initial context during relearning to recall the appropriate mapping.Modified multi-walled carbon nanotubes (f-MWCNTs) and hydroxyapatite nanorods (n-HA) were reinforced into polypropylene (PP) with the support of a melt compounding approach. Varying composition of f-MWCNTs (0.1-0.3 wt.%) and nHA (15-20 wt.%) were reinforced into PP, to obtain biocomposites of different compositions. The morphology, thermal and mechanical characteristics of PP/n-HA/f-MWCNTs were observed. Tensile studies reflected that the addition of f-MWCNTs is advantageous in improving the tensile strength of PP/n-HA nanocomposites but decreases its Young's modulus significantly. Based on the thermal study, the f-MWCNTs and n-HA were known to be adequate to enhance PP's thermal and dimensional stability. Furthermore, MTT studies proved that PP/n-HA/f-MWCNTs are biocompatible. Consequently, f-MWCNTs and n-HA reinforced into PP may be a promising nanocomposite in orthopedics industry applications such as the human subchondral bone i.e. patella and cartilage and fabricating certain light-loaded implants.The elastic responsiveness of single cellulose nanofibres is important for advanced analysis of biological tissues and their use in sophisticated functional materials. However, the mechanical responsiveness derived from the twisted structure of cellulose nanofibres (CNFs) has remained unexplored. In this study, finite element simulations were applied to characterize the deformation response derived from the torsional structure by performing tensile and bending tests of an unconventionally very long and twisted rod model, having the known dimensional parameters and properties of CNFs. The antagonistic action of two types of structural elements (a contour twist and a curvilinear coordinate) was found to result in an irregular deformation response but with only small fluctuations. The contour twist generated rotational displacements under tensile load, but the curvilinear coordinate suppressed rotational displacement. Under bending stress, the contour twist minimized irregular bending deformation because of the orthotropic properties and made the bending stress transferability a highly linear response.The retrospective study aimed to investigate the relationship between lumbar lordosis morphology, pelvic incidence and paraspinal muscle. It enrolled asymptomatic adult volunteers aged between 18 and 45 years old. Lumbar lordosis morphology, consisting of total lumbar lordosis (LL), proximal lumbar lordosis (PLL), distal lumbar lordosis (DLL), lumbar lordosis apex (LLA) and inflexion point, was evaluated, as well as pelvic incidence (PI) and muscularity of erector spinae (ES) and multifidus. Pearson correlation was performed to analyze the relationship between each other parameter. Cases were stratified according to pelvic incidence (very low 60°), comparison between groups was performed by univariance analysis. 87 asymptomatic adult volunteers (33 females and 54 males) were included in the study. PLL revealed a correlation with LLA (r = 0.603, p = 0.002) and inflexion point (r = 0.536, p = 0.004), but did not DLL with LL apex (r = 0.204, p = 0.058) or inflexion point (r = 0.210, p = 0.051). PI revealed a greater correlation with PLL (r = -0.673, p less then 0.001) than with DLL (r = -0.237, p = 0.045). Linear stepwise regression analysis also exhibited the correlation between PI and PLL (R2 = 0.452, PLL = 16.2-0.61 * PI, p less then 0.001). ES muscularity correlated with LL apex (r = -0.279, p = 0.014) and inflexion point (r = -0.227, p = 0.047). Stratification by PI demonstrated PLL increased across groups (p less then 0.001), but DLL was comparable between low and moderate PI group (p = 0.329). Lumbar lordosis morphology appears to accommodate to pelvic incidence and erector spinae muscularity. Proximal lumbar lordosis has a bigger correlation with pelvic incidence than the distal lumbar lordosis. The results are helpful for restoring a rational lumbar lordosis shape in long fusion surgery.We monitored the circulating strains and genetic variation among seasonal influenza A and B viruses in Thailand between July 2017 and March 2020. The hemagglutinin gene was amplified and sequenced. We identified amino acid (AA) changes and computed antigenic relatedness using the Pepitope model. Phylogenetic analyses revealed multiple clades/subclades of influenza A(H1N1)pdm09 and A(H3N2) were circulating simultaneously and evolved away from their vaccine strain, but not the influenza B virus. The predominant circulating strains of A(H1N1)pdm09 belonged to 6B.1A1 (2017-2018) and 6B.1A5 (2019-2020) with additional AA substitutions. Clade 3C.2a1b and 3C.2a2 viruses co-circulated in A(H3N2) and clade 3C.3a virus was found in 2020. The B/Victoria-like lineage predominated since 2019 with an additional three AA deletions. Antigenic drift was dominantly facilitated at epitopes Sa and Sb of A(H1N1)pdm09, epitopes A, B, D and E of A(H3N2), and the 120 loop and 190 helix of influenza B virus. Moderate computed antigenic relatedness was observed in A(H1N1)pdm09. The computed antigenic relatedness of A(H3N2) indicated a significant decline in 2019 (9.17%) and 2020 (- 18.94%) whereas the circulating influenza B virus was antigenically similar (94.81%) with its vaccine strain. Our findings offer insights into the genetic divergence from vaccine strains, which could aid vaccine updating.The Zarga and Ghazal formations constitute important reservoirs across the Muglad Basin, Sudan. Nevertheless, the sedimentology and diagenesis of these reservoir intervals have hitherto received insignificant research attention. Detailed understanding of sedimentary facies and diagenesis could enhance geological and geophysical data for better exploration and production and minimize risks. In this study, subsurface reservoir cores representing the Zarga formation (1114.70-1118.50 m and 1118.50-1125.30 m), and the Ghazal formation (91,403.30-1406.83 m) were subjected to sedimentological (lithofacies and grain size), petrographic/mineralogic (thin section, XRD, SEM), and petrophysical (porosity and permeability) analyses to describe their reservoir quality, provenance, and depositional environments. Eight (8) different lithofacies, texturally characterized as moderately to well-sorted, and medium to coarse-grained, sub-feldspathic to feldspathic arenite were distinguished in the cored intervals. Mono-crystalline quartz (19.